Results 81 to 90 of about 65,817 (260)

Ac‐SDKP modulates apoptosis via HSP27 and the FAS/FASL and mitochondrial axes

Animal Models and Experimental Medicine, EarlyView.
Schematic diagram of Ac‐SDKP regulating the FAS/FASL and mitochondrial apoptosis pathways via HSP27. Ac‐SDKP inhibits HSP27 expression, activates the FAS/FASL pathway and Caspase‐3 signaling, increases Caspase‐8 and Caspase‐3 expression, and induces cell apoptosis.
Wenxin Guo, Jinyin Yan, Wenli Li, Jin Wang, Lu Liu, Chengmei Zhang, Wei Cao, Shanshan Yao, Haibo Gong, Yi He, Zihan Zhou, Siyan Chen, Li Feng, Haijing Deng   +13 more
wiley   +1 more source

Prophylactic Enoxaparin Reduces Symptomatic Venous Thromboembolism Compared With No Chemoprophylaxis Within 95 Days After Knee Arthroscopy

Arthroscopy, EarlyView.
Purpose To investigate whether prophylactic use of low‐molecular‐weight heparin (enoxaparin) after knee arthroscopy reduces the incidence of symptomatic venous thromboembolism (VTE) compared with no postoperative pharmacological prophylaxis. Methods We conducted a population‐based cohort study using linked national insurance and hospital data from ...
Aylin Albrecht, Lorenz Kapral, Felix Gruber, Christoph Dibiasi, Oliver Kimberger, Christian Albrecht   +5 more
wiley   +1 more source

ANK1 and EPB41 Variants and The Risk of Glucocorticoid‐Induced Osteonecrosis

Arthritis &Rheumatology, EarlyView.
Objective Steroid‐induced osteonecrosis of the femoral head (SONFH) is a refractory skeletal disorder influenced by genetic and environmental factors. However, conclusive pathogenic genetic evidence remains elusive due to the limited exploration of rare damaging variants. In this study, we aimed to identify rare variants associated with SONFH.
Shengbao Chen, Xianmin Zhu, Zhongzhong Chen, Wei Chen, Hussam Alkaissi, Zeng Zhang, Yun Gao, Junhui Yin, Xiangtian Yu, Qiong Fu, Youshui Gao, Zhenzhong Zhu, Qianying Cai, Pengwei Zhang, Weibin Chen, Xin Zhao, Xiaojin Wu, Karel Pacak, Dongxu Jin, Chunde Bao, Zhengping Zhuang, Changqing Zhang   +21 more
wiley   +1 more source

Clinical and epidemiological profile of patients who seek post-exposure prophylaxis after sexual exposure to HIV and their adherence to the medication regimen in a specialized center in Cascavel, Paraná, Brazil

DST, 2019
Introduction: Post-Exposure Prophylaxis (PEP) is part of a new strategy for the prevention of Human Immunodeficiency Virus transmission adopted by the Brazilian Ministry of Health.
Vania Orlandi, Dilson Fronza, Douglas Soltau Gomes, Josana Aparecida Dranka Horvath, Winny Hirome Takahashi Yonegura   +4 more
doaj  

Efficacy and Safety of Nanoencapsulated Sirolimus Plus Pegadricase: Results From the Randomized, Placebo‐Controlled Phase 3 Trials

Arthritis &Rheumatology, EarlyView.
Objective DISSOLVE I and II examined the efficacy and safety of nanoencapsulated sirolimus (NAS) plus pegadricase (NASP) in patients with uncontrolled gout (UG). Methods In these double‐blind, placebo‐controlled Phase 3 trials of NASP, patients were randomized 1:1:1 to infusions of high‐dose (HD) or low‐dose (LD) NAS plus pegadricase (HD NASP, LD NASP,
Herbert S. B. Baraf, Puja P. Khanna, Milan Petronijevic, Mamuka Lortkipanidze, Anand Patel, Kwabena Ayesu, Michael H. Pillinger, Atul Singhal, Joanna Sobierska, Jacquie Christie, Peter Traber, Rehan Azeem, Wesley DeHaan, Hugues Santin‐Janin, Bhavisha Desai, Alan Kivitz   +15 more
wiley   +1 more source

Lateral and Anterior Closing Wedge “9/9” Degree Osteotomy to Correct Both Tibia Vara and Excessive Tibial Slope

Arthroscopy Techniques, EarlyView.
Abstract High tibial osteotomy is a key option for patients with unicompartmental overload or instability. Although coronal correction for varus deformity is well established, excessive posterior tibial slope (PTS) is increasingly recognized as a contributor to anterior cruciate ligament graft failure.
Julien Druel, Antoine Piercecchi, Chris Wilson, Maher Ghandour, Kristian Kley, Matthieu Ollivier   +5 more
wiley   +1 more source

Occupational post-exposure HIV prophylaxis.

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 2004
HIV and other bloodborne infectious agents, such as hepatitis B or C, can be transmitted to health care workers during occupational exposure. In all occupational exposure incidents proper documentation is essential in order to claim compensation at a later date.
openaire   +2 more sources

Arthroscopic Radial Styloidectomy: An All‐Dorsal Two‐Portal Surgical Technique

Arthroscopy Techniques, EarlyView.
Abstract Radial‐sided wrist pain and impingement are recognized sources of persistent symptoms following 4‐corner fusion, often related to radioscaphoid contact and progressive degenerative changes. Radial styloidectomy has been described as a surgical option to address this pathology while preserving carpal stability.
Frank L. Vazquez, Anna L. Gorsky, Kier Blevins, Krishna N. Chopra, Nina Suh, Eric R. Wagner   +5 more
wiley   +1 more source

Emergent informal use of doxycycline post- and pre-exposure prophylaxis among men who have sex with men and transgender and gender diverse people, the Netherlands, 2024

Eurosurveillance
BACKGROUND Doxycycline post-exposure and pre-exposure prophylaxis (doxyPEP/PrEP) to prevent sexually transmitted infections (STIs) is not part of standard practice in the Netherlands but may be used informally (without prescription).
Vita W Jongen
doaj   +1 more source

Soft Cerclage in Addition to Rigid Fixation for Surgical Management of Displaced Comminuted Midshaft Clavicle Fractures

Arthroscopy Techniques, EarlyView.
Abstract Midshaft clavicle fractures are one of the most common upper extremity fractures among adults. When displaced, open reduction and internal fixation may be indicated, most commonly performed using single or dual plating. Cerclage techniques can be used in addition to lag screws and plate fixation to better capture and reduce inferior and ...
Donovan A. Bronstein, Olivia M. Jochl, Jack H. Kramer, Eddie K. Afeste, Joseph J. Ruzbarsky   +4 more
wiley   +1 more source