Results 51 to 60 of about 5,828,957 (159)

Oral finasteride use and sexual adverse events: signal detection from disproportionality analyses of data from the United States Food and Drug Administration Adverse Event Reporting System

Journal of Dermatological Treatment
Background Oral finasteride 1 milligram (1 mg) daily—which is a 5-alpha reductase inhibitor (5-ARI) approved by the Food and Drug Administration (FDA) for androgenetic alopecia—is linked to sexual adverse events (AEs). However, it remains unclear whether
Aditya K. Gupta, Mesbah Talukder, Greg Williams, Mary A. Bamimore   +3 more
doaj   +1 more source

Safety Profile of Finasteride: Distribution of Adverse Effects According to Structural and Informational Dichotomies of the Mind/Brain

, 2017
Finasteride is currently used extensively for male androgenic alopecia and benign prostatic hyperplasia; however, some adverse effects are severe and even persistent after treatment cessation, the so-called ‘post-finasteride syndrome’. The following most
Ioana Păunică, Rowland, David L, Georgescu, Simona R, Ioanel Sinescu, Ion G. Motofei, Sinescu, Ioanel, Simona R. Georgescu, Mirela Manea, Motofei, Ion G, Manea, Mirela, Păunică, Ioana, David L. Rowland   +11 more
core   +1 more source

An (Ir)reversible Affection of the Sexual Sphere: A Case Report

Journal of Psychosexual Health
Background: Finasteride, a 5α-reductase inhibitor (5αRI) for benign prostatic hyperplasia and androgenetic alopecia (AGA), has been linked to persistent multisystemic symptoms—most often sexual dysfunction—that may appear during or after use and persist ...
Sofia Mendes Cunha
doaj   +1 more source

Post-Finasteride Syndrome: About 2 Cases and Review of the Literature

Andrology-Open Access, 2016
Introduction: Finasteride is widely used in the treatment of benign prostatic hyperplasia and androgenetic alopecia. Persistent sexual adverse events in patients that withdraw the drug was poorly studied. Materials and methods: case report study of two clinical cases of post-finasteride syndrome.
Alejandro Silva Garreton, Gaston Rey Valzacchi, Omar Layus   +2 more
openaire   +1 more source

Amyloid β Instigates Cardiac Neurotrophic Signaling Impairment, Driving Alzheimer's Associated Heart Disease

Advanced Science, Volume 13, Issue 20, 9 April 2026.
This research identified cardiac amyloid pathology, neurotrophic factor depletion, and reduced myocardial nerve function in a transgenic model of cerebral amyloidosis (Tg2576), Aβ‐challenged cardiomyocytes, and in human AD heart tissue. These findings carry significant diagnostic and therapeutic implications, emphasizing the role of neuro‐signaling ...
Andrea Elia, Rebecca Parodi‐Rullan, Rafael Vazquez‐Torres, Ashley Carey, Huaqing Zhao, Sabzali Javadov, Silvia Fossati   +6 more
wiley   +1 more source

Research Progress on Platelet‐Rich Plasma (PRP) in the Treatment of Androgenetic Alopecia

Journal of Cosmetic Dermatology, Volume 25, Issue 4, April 2026.
ABSTRACT Background Androgenetic alopecia (AGA) is the most common cause of progressive hair loss, significantly affecting quality of life. Current therapies, such as minoxidil, finasteride, and hair transplantation, show variable efficacy and may be associated with adverse effects.
Zetian Zhong, Li Luo, Lixiang Zhao, Xupeng Yue, Yanxin Lu   +4 more
wiley   +1 more source

Treatment of male rats with finasteride, an inhibitor of 5alpha-reductase enzyme, induces long-lasting effects on depressive-like behavior, hippocampal neurogenesis, neuroinflammation and gut microbiota composition

, 2019
Persistent alteration of plasma neuroactive steroid levels associated with major depression has been recently reported in men after the suspension of the treatment for androgenetic alopecia with finasteride, an inhibitor of the enzyme 5alpha-reductase ...
S. Giatti, Melcangi, R. C., L. M. Garcia-Segura, Barcella, Matteo, J. L. Trejo, García-Segura, Luis M., R. C. Melcangi., S. Diviccaro, M. Barcella, F. Borgo, Borghi, E., Borgo, Francesca, Trejo, José L., E. Borghi, Giatti, S., Diviccaro, Silvia   +15 more
core   +1 more source

Post-COVID-19 syndrome and fibromyalgia

, 2022
A growing body of evidence is suggesting the possible subacute and long-term effects in patients suffering from COVID-19, affecting multiple organ systems.
Giacomelli R., Ursini F., Ruscitti P.
core   +1 more source

An Exploratory Preclinical In Vivo Pilot Study Evaluating the Hair Growth–Promoting Effects of Rosmarinus officinalis and Ricinus communis Combination

BioMed Research International, Volume 2026, Issue 1, 2026.
Background Hair loss is a common condition with significant psychosocial impact. Although pharmacological treatments such as minoxidil are available, their long‐term use may be associated with adverse effects. Plant‐derived products are widely used in traditional medicine for hair care; however, scientific validation of their efficacy remains limited ...
Alex Mathenge, Elizabeth Odongo, Ruth Mauti, Fednard Osee, Poorani Gurumallesh Prabu   +4 more
wiley   +1 more source

An observational retrospective evaluation of 79 young men with long-term adverse effects after use of finasteride against androgenetic alopecia [PDF]

, 2016
Concern regarding adverse effects of finasteride is increasing. We aimed to determine the type and frequency of symptoms in men having long-term sexual and non-sexual side effects after finasteride treatment (a condition recently called post-finasteride ...
CHIRIACÒ, GIOVANNI, TROMBETTA, CARLO, Cauci, S, MAZZON, GIORGIO   +3 more
core   +2 more sources