Results 41 to 50 of about 6,092,576 (159)

Gut Inflammation Induced by Finasteride Withdrawal: Therapeutic Effect of Allopregnanolone in Adult Male Rats

Biomolecules, 2022
The treatment with finasteride (i.e., an inhibitor of 5α-reductase) may be associated with different side effects (i.e., depression, anxiety, cognitive impairment and sexual dysfunction) inducing the so-called post finasteride syndrome (PFS).
Silvia Diviccaro, Silvia Giatti, Lucia Cioffi, Eva Falvo, Monika Herian, Donatella Caruso, Roberto Cosimo Melcangi   +6 more
doaj   +1 more source

Finasteride for hair loss: a review

, 2021
Background and Objectives Finasteride 1 mg/day is indicated for androgen-dependent conditions such as male androgenetic alopecia (AGA). Methods The literature is comprehensively summarized on the pharmacodynamics, pharmacokinetics, mechanism of action ...
M. Venkataraman, A. K. Gupta, M. A. Bamimore, M. Talukder   +3 more
core   +1 more source

The Effects of Finasteride on Parity in Female Drosophila Melanogaster [PDF]

, 2023
Finasteride has been used to treat male pattern baldness and benign prostate hyperplasia and could potentially treat female pattern baldness and polycystic ovary syndrome.
Turner, Carly, Mitchell, Carol, Bruno, Trey, Sandell, Dominic, Guildin, Michael   +4 more
core   +1 more source

Persistent Sexual, Emotional, and Cognitive Impairment Post-Finasteride

American Journal of Men's Health, 2015
Finasteride is a synthetic 5-α reductase inhibitor, which prevents the conversion of testosterone to dihydrotestosterone and has been used for more than 20 years in the treatment of male pattern hair loss.
Christine Anne Ganzer PhD, Alan Roy Jacobs MD, Farin Iqbal   +2 more
doaj   +1 more source

Alterations of gut microbiota composition in post-finasteride patients: a pilot study [PDF]

, 2021
Purpose: Post-finasteride syndrome (PFS) has been reported in a subset of patients treated with finasteride (an inhibitor of the enzyme 5alpha-reductase) for androgenetic alopecia. These patients showed, despite the suspension of the treatment, a variety
Diviccaro S., Borgo F., Falvo E., Macandog A. D., Giatti S., Cavaletti G., Melcangi R. C.   +6 more
core   +1 more source

An observational retrospective evaluation of 79 young men with long-term adverse effects after use of finasteride against androgenetic alopecia [PDF]

, 2016
Concern regarding adverse effects of finasteride is increasing. We aimed to determine the type and frequency of symptoms in men having long-term sexual and non-sexual side effects after finasteride treatment (a condition recently called post-finasteride ...
CHIRIACÒ, GIOVANNI, TROMBETTA, CARLO, Cauci, S, MAZZON, GIORGIO, Trombetta, C., Chiriacò, G, CAUCI, Sabina, Mazzon, G   +7 more
core   +2 more sources

Exploring rat corpus cavernosum alterations induced by finasteride treatment and withdrawal [PDF]

, 2023
Despite its efficacy for treating androgenetic alopecia, finasteride, an inhibitor of 5α-reductase (i.e., the enzyme converting testosterone, T, into dihydrotestosterone, DHT), is associated with several side effects including sexual dysfunction (e.g ...
Caruso, Donatella, Matteo Audano, Audano, Matteo, Monika Herian, Silvia Giatti, Donatella Caruso, Lucia Cioffi, Herian, Monika, RC Melcangi, Roberto Cosimo Melcangi, Mitro, Nico, Silvia Diviccaro, Giatti, Silvia, Cioffi, Lucia, Diviccaro, Silvia, Nico Mitro   +15 more
core   +1 more source

Safety Profile of Finasteride: Distribution of Adverse Effects According to Structural and Informational Dichotomies of the Mind/Brain

, 2017
Finasteride is currently used extensively for male androgenic alopecia and benign prostatic hyperplasia; however, some adverse effects are severe and even persistent after treatment cessation, the so-called ‘post-finasteride syndrome’. The following most
Ioana Păunică, Rowland, David L, Georgescu, Simona R, Ioanel Sinescu, Ion G. Motofei, Sinescu, Ioanel, Simona R. Georgescu, Mirela Manea, Motofei, Ion G, Manea, Mirela, Păunică, Ioana, David L. Rowland   +11 more
core   +1 more source

Androgenic alopecia; the risk–benefit ratio of Finasteride

Journal of Mind and Medical Sciences, 2018
Finasteride is currently approved and largely used as a therapeutic option for androgenetic alopecia. Apparently a safe drug and effective at the onset, several concerns appeared over time regarding the frequency and magnitude of finasteride adverse ...
David L. Rowland, Ion G. Motofei, Ioana Păunică, Petrișor Banu, Mihaela F. Nistor, Stana Păunică, Vlad D. Constantin   +6 more
doaj   +1 more source

Androgen Receptor (AR) Gene (CAG)n and (GGN)n Length Polymorphisms and Symptoms in Young Males With Long-Lasting Adverse Effects After Finasteride Use Against Androgenic Alopecia

Sexual Medicine, 2017
Introduction: Long-term adverse symptoms of men who used oral finasteride against androgenic alopecia have been recently described as post-finasteride syndrome (PFS).
Sabina Cauci, PhD, Giovanni Chiriacò, MD, Erika Cecchin, MS, Giuseppe Toffoli, MD, Serena Xodo, MD, Giuseppe Stinco, MD, Carlo Trombetta, MD   +6 more
doaj   +1 more source