Results 21 to 30 of about 6,092,576 (159)
Post-finasteride syndrome: a surmountable challenge for clinicians [PDF]
Fertility and Sterility, 2020 Post-finasteride syndrome (PFS) is a constellation of serious adverse side effects manifested in clinical symptoms that develop and persist in patients during and/or after discontinuing finasteride treatment in men with pattern hair loss (androgenetic alopecia) or benign prostatic hyperplasia.
Abdulmaged M Traish
exaly +3 more sources
Differential Gene Expression in Post-Finasteride Syndrome Patients
Journal of Sexual Medicine, 2021 ABSTRACTBackgroundAn organic etiology underpinning post-finasteride syndrome, a constellation of persistent sexual, neuropsychiatric, and somatic symptoms reported by men exposed to 5-alpha-reductase inhibitors (5ARIs), is debated. Persistent changes in neurosteroid levels or androgen receptor expression have been implicated.AimTo determine whether ...
Alexander W Pastuszak, Weitao Song
exaly +3 more sources
Atypical post-finasteride syndrome: A pharmacological riddle [PDF]
Indian Journal of Pharmacology, 2016 Finasteride and dutasteride are commonly used 5-alpha reductase inhibitors. While finasteride is a selective inhibitor of 5-alpha reductase Type II, dutasteride inhibits 5- alpha reductase Type I and II. The United States Food and Drug Administration approved the use of finasteride for benign prostatic hypertrophy (BPH) as well as androgenic alopecia ...
Gupta, Anita K. +2 more
openaire +4 more sources
European Urology Open Science, 2023 Finasteride competitively inhibits 5α-reductase (5-AR) isoenzymes, which blocks dihydrotestosterone (DHT) production, thereby reducing DHT. Finasteride is used in the management of benign prostatic hyperplasia (BPH) and androgenic alopecia.
Haidar Al Saffar +5 more
doaj +2 more sources
Post-finasteride syndrome – does it really exist?
Aging Male, 2019 Inhibitors of 5α-steroid reductase are drugs used to treat androgen-dependent conditions including prostate diseases and androgenic alopecia. Finasteride was the first on the market and is currently the most widely used inhibitor. Dutasteride was the second inhibitor to be approved and has a similar safety profile.
Michal Rabijewski +2 more
exaly +3 more sources
Post-Finasteride Syndrome: An Induced Delusional Disorder with the Potential of a Mass Psychogenic Illness? [PDF]
Skin Appendage Disorders, 2019 Post-finasteride syndrome (PFS) has been claimed to occur in men who have taken oral finasteride to treat either hair loss or benign prostatic hyperplasia, independent of age, dosage, or indication. By definition, the condition is characterized by sexual dysfunction, somatic symptoms, and psychological disorders that persist after cessation of ...
Ralph M, Trüeb +3 more
openaire +3 more sources
The postfinasteride syndrome; an overview [PDF]
Journal of Mind and Medical Sciences, 2016 As a 5-α reductase inhibitor, Finasteride has proven effective in ameliorating two conditions documented to be androgen dependent, namely male androgenic alopecia and benign prostatic hyperplasia. Therapeutic results are maintained as long as the drug is
David L. Rowland +9 more
doaj +2 more sources
Emotional Consequences of Finasteride: Fool’s Gold
American Journal of Men's Health, 2018 Androgenetic alopecia, the gradual, progressive loss of hair frequently results in psychological despair, in part related to changes in self-image. Current androgenetic alopecia treatments are limited to hair transplantation and medications that inhibit ...
Christine Anne Ganzer PhD +1 more
doaj +2 more sources
American Journal of Men's Health, 2018 Our research objective is to understand more, through subjective, self-reports on discussion boards/forums, persons’ experiences associated with the use of drugs that alter androgen metabolism, such as finasteride.
Alicia A. Walf +2 more
doaj +2 more sources
Finasteride as a model for personalized medicine [PDF]
Journal of Mind and Medical Sciences, 2017 The side effects of Finasteride are currently a subject of controversy. Some studies report minor or acceptable adverse effects, which decrease after a variable period of time so that they do not necessitate terminating Finasteride administration ...
Ion G. Motofei +5 more
doaj +2 more sources