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Post-finasteride syndrome: a surmountable challenge for clinicians [PDF]

open access: bronzeFertility and Sterility, 2020
Post-finasteride syndrome (PFS) is a constellation of serious adverse side effects manifested in clinical symptoms that develop and persist in patients during and/or after discontinuing finasteride treatment in men with pattern hair loss (androgenetic alopecia) or benign prostatic hyperplasia.
Abdulmaged M. Traish
exaly   +5 more sources

Post-finasteride syndrome – does it really exist? [PDF]

open access: bronzeThe Aging Male, 2019
Inhibitors of 5α-steroid reductase are drugs used to treat androgen-dependent conditions including prostate diseases and androgenic alopecia. Finasteride was the first on the market and is currently the most widely used inhibitor. Dutasteride was the second inhibitor to be approved and has a similar safety profile.
Radosław Maksym   +2 more
exaly   +5 more sources

Post-Finasteride Syndrome (PFS) Update: Point/Counterpoint [PDF]

open access: bronzeInternational Society of Hair Restoration Surgery, 2016
1. Edwin S. Epstein, MD, FISHRS (esehairmd{at}gmail.com) 1. Richmond, Virginia, USA At the ISHRS 2015 Annual Scientific Meeting in Chicago, we heard an update on the constellation of symptoms that has come to be known as Post-Finasteride Syndrome (PFS).
Edwin S. Epstein
openalex   +2 more sources

Finasteride as a model for personalized medicine [PDF]

open access: yesJournal of Mind and Medical Sciences, 2017
The side effects of Finasteride are currently a subject of controversy. Some studies report minor or acceptable adverse effects, which decrease after a variable period of time so that they do not necessitate terminating Finasteride administration ...
Ion G. Motofei   +5 more
doaj   +4 more sources

The post-finasteride syndrome: possible etiological mechanisms and symptoms

open access: hybridInternational Journal of Impotence Research, 2023
Finasteride and dutasteride, synthetic 5α-reductase inhibitors (5ARIs) are recommended in many guidelines for the treatment of benign prostatic hyperplasia/lower urinary tract symptoms and alopecia despite a variety of side effects like sexual, neurological, psychiatric, endocrinological, metabolic and ophthalmological dysfunctions and the increased ...
Herman H. J. Leliefeld   +2 more
openalex   +3 more sources

Trazodone and chlorpromazine a proposal treatment for syndrome post-finasteride and syndrome of post-selective serotonin reuptake inhibitors (post-SSRI) [PDF]

open access: hybridWorld Journal of Biology Pharmacy and Health Sciences, 2023
Erectile dysfunction caused by medications are probably caused by the disconnection of synaptic circuits responsible for linking libido to erection. For instance, it is well known that sexual dysfunction may occur in patients treated with antidepressants like selective serotonin reuptake inhibitors, syndrome known as (post-SSRI).
Eric Almeida Xavier
  +5 more sources

Androgenic alopecia; the risk–benefit ratio of Finasteride [PDF]

open access: yesJournal of Mind and Medical Sciences, 2018
Finasteride is currently approved and largely used as a therapeutic option for androgenetic alopecia. Apparently a safe drug and effective at the onset, several concerns appeared over time regarding the frequency and magnitude of finasteride adverse ...
David L. Rowland   +6 more
doaj   +4 more sources

A Comment on the Post-Finasteride Syndrome.

open access: yesInt J Trichology, 2018
The post-Finasteride syndrome (PFS) has been claimed to occur in men who have taken oral finasteride to treat hair loss or benign prostatic hyperplasia. While the incidence of persistent sexual, mental, and physical side effects despite quitting finasteride is unknown, and the condition is not recognized by the scientific community, individuals who ...
Rezende HD, Dias MFRG, Trüeb RM.
europepmc   +4 more sources

Androgen Receptor (AR) Gene (CAG)n and (GGN)n Length Polymorphisms and Symptoms in Young Males With Long-Lasting Adverse Effects After Finasteride Use Against Androgenic Alopecia [PDF]

open access: yesSexual Medicine, 2017
Introduction: Long-term adverse symptoms of men who used oral finasteride against androgenic alopecia have been recently described as post-finasteride syndrome (PFS).
Sabina Cauci, PhD   +6 more
doaj   +4 more sources

Atypical post-finasteride syndrome: A pharmacological riddle.

open access: yesIndian J Pharmacol, 2016
Finasteride and dutasteride are commonly used 5-alpha reductase inhibitors. While finasteride is a selective inhibitor of 5-alpha reductase Type II, dutasteride inhibits 5- alpha reductase Type I and II. The United States Food and Drug Administration approved the use of finasteride for benign prostatic hypertrophy (BPH) as well as androgenic alopecia ...
Gupta AK, Sharma N, Shukla P.
europepmc   +4 more sources

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