Results 11 to 20 of about 1,831 (125)

Gut Inflammation Induced by Finasteride Withdrawal: Therapeutic Effect of Allopregnanolone in Adult Male Rats

Biomolecules, 2022
The treatment with finasteride (i.e., an inhibitor of 5α-reductase) may be associated with different side effects (i.e., depression, anxiety, cognitive impairment and sexual dysfunction) inducing the so-called post finasteride syndrome (PFS).
Silvia Diviccaro, Silvia Giatti, Lucia Cioffi, Eva Falvo, Monika Herian, Donatella Caruso, Roberto Cosimo Melcangi   +6 more
doaj   +3 more sources

5α-Reductase Isoenzymes: From Neurosteroid Biosynthesis to Neuropsychiatric Outcomes [PDF]

NeuroSci
5a-reductase (5a-R) isozymes are essential for androgen metabolism and neurosteroid biosynthesis, linking endocrinology and neuropsychiatry. This systematic review, conducted in accordance with PRISMA 2020 guidelines, aimed to synthesize current evidence
Carmen Rodriguez-Cerdeira
doaj   +2 more sources

Finasteride adverse effects and post-finasteride syndrome; implications for dentists

Journal of Mind and Medical Sciences, 2016
Finasteride is a 5α-reductase inhibitor widely used in present in the therapeutic approach of androgenic alopecia. Adverse effects consist in variable sign and symptoms, the most common being represented by mental troubles (reduced feeling of life ...
Stana Paunica, Marina Giurgiu, Andrei Vasilache, Ioana Paunica, Ion Motofei, Adriana Vasilache, Horia Traian Dumitriu, Anca Silvia Dumitriu   +7 more
doaj   +2 more sources

Exploration of the Possible Relationships Between Gut and Hypothalamic Inflammation and Allopregnanolone: Preclinical Findings in a Post-Finasteride Rat Model [PDF]

Biomolecules
Background: Finasteride, a 5α-reductase inhibitor commonly prescribed for androgenetic alopecia, has been linked to persistent adverse effects after discontinuation, known as post-finasteride syndrome (PFS).
Silvia Diviccaro, Roberto Oleari, Federica Amoruso, Fabrizio Fontana, Lucia Cioffi, Gabriela Chrostek, Vera Abenante, Jacopo Troisi, Anna Cariboni, Silvia Giatti, Roberto Cosimo Melcangi   +10 more
doaj   +2 more sources

Emotional Consequences of Finasteride: Fool’s Gold

American Journal of Men's Health, 2018
Androgenetic alopecia, the gradual, progressive loss of hair frequently results in psychological despair, in part related to changes in self-image. Current androgenetic alopecia treatments are limited to hair transplantation and medications that inhibit ...
Christine Anne Ganzer PhD, Alan Roy Jacobs MD   +1 more
doaj   +2 more sources

8679 Case: The Sexual, Physical and Psychological Effects of Post-Finasteride Syndrome [PDF]

J Endocr Soc
Abstract Disclosure: E.M. Lonergan: None. S.M. Maher: None. I. Yaseen: None. D.B. O'Shea: None. Post-finasteride syndrome (PFS) is an increasingly recognised disorder with a myriad of physical and neuropsychiatric symptoms persisting for greater than three months in a small proportion of patients treated with Finasteride ...
Lonergan, Eibhlin Marie, Maher, Sean Martin, Yaseen, Ibrahim, O'Shea, Donal Brendan   +3 more
europepmc   +2 more sources

Finasteride Side Effects and Post-Finasteride Syndrome in Male Androgenic Alopecia

Journal of Mind and Medical Sciences, 2015
Finasteride is in present a relatively frequent prescribed drug for male androgenic alopecia. The adverse effects reported by some patients seem to be notable, consisting of various (physical, mental/ neurological, sexual, etc.) manifestations which are ...
Manea Mirela, Paunica Ioana, Puiu Gabriela Maria, Manea Costin Mihnea   +3 more
doaj   +2 more sources

Multidimensional assessment of adverse events of finasteride：a real-world pharmacovigilance analysis based on FDA Adverse Event Reporting System (FAERS) from 2004 to April 2024. [PDF]

PLoS ONE
BackgroundFinasteride is commonly utilized in clinical practice for treating androgenetic alopecia, but real-world data regarding the long-term safety of its 0adverse events(AEs) remains incomplete, necessitating ongoing supplementation.
Xiaoling Zhong, Yihan Yang, Sheng Wei, Yuchen Liu   +3 more
doaj   +2 more sources

Epidemiological landscape of androgenetic alopecia in the US: An All of Us cross-sectional study. [PDF]

PLoS ONE
BackgroundAndrogenetic alopecia (AGA) is extremely prevalent with a multifactorial etiology.MaterialsWe conducted a cross-sectional study using the All of US (AoU) dataset Sept 2024 to better understand the epidemiology, social determinants and ...
Aditya K Gupta, Tong Wang, Vasiliki Economopoulos   +2 more
doaj   +2 more sources

Post-Finasteride Syndrome: Survey of Dermatologists From the Spanish Hair and Nail Disorders Group

Actas Dermo-Sifiliográficas
Background and objective: Post-finasteride syndrome (PFS) refers to a set of persistent symptoms reported by patients after discontinuation of 5-alpha-reductase inhibitors (5-ARIs).
O.M. Moreno-Arrones, D. Saceda-Corralo, J.L. Gómez-Cano, A. Gómez-Zubiaur, J.M. Mir-Bonafé, C. Serrano-Falcón, G. Garnacho-Saucedo, R. Grimalt, A. Combalia, E. Fernández, S. Vañó-Galván   +10 more
doaj   +2 more sources