Radiology Case ReportsPost hepatectomy Liver Failure (PHLF) is a fatal complication, especially after major liver resection. Insufficient remnant liver volume is a common cause of postoperative liver failure.
Anh T Pham +8 more
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Frontiers in Oncology, 2022 PurposeTo determine the predictive value of portal hypertension (PH) for the development of post-hepatectomy liver failure (PHLF) in patients with hepatocellular carcinoma (HCC).Patients and methodsThis study enrolled a total of 659 patients with HCC ...
Jitao Wang +15 more
doaj +1 more source
Systematic review and meta-analysis of thrombocytopenia as a predictor of post-hepatectomy liver failure [PDF]
HPB, 2019 We performed a systematic review and meta-analysis to assess whether thrombocytopenia constituted a risk factor for post-hepatectomy liver failure (PHLF).We searched MEDLINE and EMBASE from inception until February the 17th, 2018 for studies reporting cases of PHLF in patients with and without thrombocytopenia (defined as a platelet count below 100 or ...
Meyer, Jérémy +5 more
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Indian Journal of Anaesthesia, 2017 Background and Aims: Hepatic resection is a major surgery associated with intraoperative massive fluid shifts, blood loss, haemodynamic instability and risk of development of post-hepatectomy liver failure.
Shweta A Singh +4 more
doaj +1 more source
Optical Biomedical Imaging Reveals Criteria for Violated Liver Regenerative Potential
Cells, 2023 To reduce the risk of post-hepatectomy liver failure in patients with hepatic pathologies, it is necessary to develop an approach to express the intraoperative assessment of the liver’s regenerative potential.
Svetlana Rodimova +11 more
doaj +1 more source
Microbiota and bile acid profiles in retinoic acid-primed mice that exhibit accelerated liver regeneration. [PDF]
, 2015 Background & aimsAll-trans Retinoic acid (RA) regulates hepatic lipid and bile acid homeostasis. Similar to bile acid (BA), RA accelerates partial hepatectomy (PHx)-induced liver regeneration.
Hu, Ying +2 more
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Hepatectomy risk assessment with functional magnetic resonance imaging (HEPARIM)
BMC Cancer, 2021 Background Post hepatectomy liver failure (PHLF) remains a significant risk in patients undergoing curative liver resection for cancer, however currently available PHLF risk prediction investigations are not sufficiently accurate.
Mohamed Elsharif +13 more
doaj +1 more source
RAS mutation status predicts survival and patterns of recurrence in patients undergoing hepatectomy for colorectal liver metastases. [PDF]
, 2013 ObjectiveTo determine the impact of RAS mutation status on survival and patterns of recurrence in patients undergoing curative resection of colorectal liver metastases (CLM) after preoperative modern chemotherapy.BackgroundRAS mutation has been reported ...
Aloia, Thomas A +8 more
core +1 more source
Prediction of small for size syndrome after extended hepatectomy: Tissue characterization by relaxometry, diffusion weighted magnetic resonance imaging and magnetization transfer. [PDF]
PLoS ONE, 2018 This study aimed to monitor the course of liver regeneration by multiparametric magnetic-resonance imaging (MRI) after partial liver resection characterizing Small-for-Size Syndrome (SFSS), which frequently leads to fatal post-hepatectomy liver failure ...
Christian Eberhardt +6 more
doaj +1 more source
Post hepatectomy liver failure – A comprehensive review of current concepts and controversies
Annals of Medicine and Surgery, 2018 Post hepatectomy liver failure (PHLF) comprises of a conundrum of symptoms and signs following major hepatic resections. The pathophysiology essentially revolves around disruption of the normal hepatocyte regeneration and disturbed liver homeostasis. Prompt identification of the pre-operative predictors of PHLF in the form of biochemical parameters and
S. Ray, N.N. Mehta, A. Golhar, S. Nundy
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