Results 51 to 60 of about 21,239 (217)
Mini-invasive approaches in hepatic surgery are associated with a significant decrease in the incidence of post-operative morbidity and liver failure. Intraoperative blood loss represents the major intraoperative accident during hepatectomy. Infrahepatic
Francesco Marchegiani+3 more
doaj +1 more source
c‐Rel–dependent Chk2 signaling regulates the DNA damage response limiting hepatocarcinogenesis
In response to genotoxic injury, c‐Rel upregulates ATM‐Chk2‐p53 pathway DNA damage proteins to limiting hepatocarcinogenesis. Abstract Background and Aims Hepatocellular carcinoma (HCC) is a leading cause of cancer‐related death. The NF‐κB transcription factor family subunit c‐Rel is typically protumorigenic; however, it has recently been reported as a
Jack Leslie+17 more
wiley +1 more source
Systematic review of MARS treatment in post-hepatectomy liver failure [PDF]
Post-hepatectomy liver failure (PHLF) remains a serious complication after major liver resection with severe 90-day mortality. Molecular adsorbent recirculating system (MARS) is a potential treatment option in PHLF. This systematic review sought to analyze the experiences and results of MARS in PHLF.Following the PRISMA guidelines, a systematic ...
Thomas M. van Gulik+2 more
openaire +3 more sources
PurposeThe impact of sarcopenia on the future liver remnant (FLR) growth after portal vein occlusion, including portal vein embolization (PVE) and associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) has gained increasing ...
Qiang Wang+7 more
doaj +1 more source
Abstract End‐ischemic viability testing by normothermic machine perfusion (NMP) represents an effective strategy to recover liver grafts having initially been discarded for liver transplantation (LT). However, its results in the setting of significant (≥30%) macrovesicular steatosis (MaS) have not been specifically assessed.
Damiano Patrono+8 more
wiley +1 more source
Risk factors for post-hepatectomy liver failure in 80 patients
Post-hepatectomy liver failure (PHLF) is a serious complication and a leading cause of death after hepatectomy, an accurate prediction of PHLF is important for improvement of prognosis after hepatectomy.To retrospectively analyze the risk factors for postoperative liver failure in patients undergoing hepatectomy for liver tumors.The clinical data of 80
Ying Xing+4 more
openaire +3 more sources
Liver Transplantation in Patients with Post-Hepatectomy Liver Failure – A Northern European Multicenter Cohort Study [PDF]
Liver transplantation (LTX) has been described as a rescue treatment option in severe, intractable post-hepatectomy liver failure (PHLF), but is not considered to be indicated for this condition by many hepatobiliary and transplant surgeons. In this article we describe the clinical experience of five northern European tertiary centers in using LTX to ...
Sparrelid, Ernesto+13 more
openaire +5 more sources
Non-invasive tests for the prediction of post-hepatectomy liver failure in the elderly [PDF]
n ...
Giovanni Marasco+9 more
openalex +6 more sources
Xenogeneic Heterotopic Auxiliary Liver transplantation (XHALT) promotes native liver regeneration in a Post-Hepatectomy Liver failure model. [PDF]
The liver's regenerative capacity is unique, but too small a segment can overwhelm its ability to simultaneously regenerate and support the host, resulting in liver dysfunction and death.
Nalu Navarro-Alvarez+11 more
doaj +1 more source
Post hepatectomy liver failure (PHLF) – Recent advances in prevention and clinical management [PDF]
Posthepatectomy liver failure (PHLF) is a relatively rare but feared complication following liver surgery, and associated with high morbidity, mortality and cost implications. Significant advances have been made in detailed preoperative assessment, particularly of the liver function in an attempt to predict and mitigate this complication.A detailed ...
Rahul Deshpande+2 more
openaire +5 more sources