Results 51 to 60 of about 7,385,684 (193)

Portal vein embolization with absolute ethanol to induce hypertrophy of the future liver remnant

CVIR Endovascular, 2022
Background Preoperative portal vein embolization (PVE) is widely used prior to major liver resection to reduce the risk of post-hepatectomy liver failure (PHLF). We evaluated the efficacy and safety of PVE using absolute ethanol.
Cositha Santhakumar, William Ormiston, John L McCall, Adam Bartlett, David Duncan, Andrew Holden   +5 more
doaj   +1 more source

Analysis of patients with acute liver failure after liver surgery: Single center experience

, 2022
Liver transplantation is the lifesaving treatment option for rare acute liver failure that develops due to iatrogenic bile duct injuries or after major hepatectomy.
Tevfik Sahin, Akile Zengin, Mukadder Ispir, Sezai Yilmaz, Kutay Saglam, Sertac Usta, İspir, Mukadder, YILMAZ, SEZAİ, Zengin, Akile, Şahin, Tevfik Tolga, Yılmaz, Sezai, Usta, Sertaç, Sağlam, Kutay   +12 more
core   +1 more source

Case Report: Preoperative treatment of portal hypertension by splenic artery embolization for safe major hepatectomy: experience in three patients

Frontiers in Surgery
Post-resection portal pressure is one of the most important determinants of post-hepatectomy liver failure. Therefore, preexisting portal hypertension is a significant risk factor for PHLF.
Duygu Gürel, Duygu Gürel, Tevfik Güzelbey, Oğuzhan Aydın, Serhat Kaya, Özgür Bostancı, İlgin Özden, İlgin Özden   +7 more
doaj   +1 more source

Early postoperative arterial lactate concentrations to stratify risk of post-hepatectomy liver failure.

, 2021
BACKGROUND Post-hepatectomy liver failure (PHLF) represents the major determinant for death after liver resection. Early recognition is essential.
Cardini, Benno, Haselmann, Clemens, Braunwarth, Eva, Malik, Hassan, Öfner, Dietmar, Roberts, Keith J, Primavesi, Florian, Pufal, Kamil, Connolly, Catherine E, Hackl, Hubert, Niederwieser, Thomas, Dasari, Bobby V M, Stättner, Stefan, Szatmary, Peter, Benno Cardini, Clemens Haselmann, Thomas Niederwieser, Dietmar Öfner, Roberts, Keith, Peter Szatmary, Catherine E Connolly, Florian Primavesi, Keith Roberts, Kamil Pufal, Hubert Hackl, Eva Braunwarth, Stefan Stättner, Bobby V M Dasari, Hassan Malik   +28 more
core   +1 more source

Using the comprehensive complication index to rethink the ISGLS criteria for post-hepatectomy liver failure in an international cohort of major hepatectomies [PDF]

, 2021
Objective: To compare different criteria for post-hepatectomy liver failure (PHLF) and evaluate the association between International Study Group of Liver Surgery (ISGLS) PHLF and the Comprehensive Complication Index (CCI)" and 90-day mortality. Summary
Rashidian, Niki, Park, Keon Min, Benedetti Cacciaguerra, Andrea, Hoffman, Daniel, Conroy, Patricia C, Adam, Mohamed Abdelgadir, Cacciaguerra, Andrea Benedetti, Hilal, Mohammad Abu, Rashidian, Nikdokht, Calthorpe, Lucia, Conroy, Patricia, Abu Hilal, Mohammad, Group, International Post-Hepatectomy Liver Failure Study, Post-Hepatectomy Liver Failure, Int, Hibi, Taizo, Alseidi, Adnan, Wang, Jaeyun, Mohamed Abdelgadir Adam, Daniel Hoffman, Lucia Calthorpe, Keon Min Park, Adnan Alseidi, Taizo Hibi, Mohammad Abu Hilal, Jaeyun Wang, Andrea Benedetti Cacciaguerra, Patricia C. Conroy, null null, Nikdokht Rashidian   +28 more
core   +1 more source

Mesenchymal stem cells ameliorate lipid metabolism through reducing mitochondrial damage of hepatocytes in the treatment of post-hepatectomy liver failure

Cell Death and Disease, 2021
Hepatectomy is an effective therapeutic strategy for many benign and malignant liver diseases, while the complexity of liver anatomy and the difficulty of operation lead to complications after hepatectomy. Among them, post-hepatectomy liver failure (PHLF)
Jing-lin Wang, Hao-ran Ding, Chen-yan Pan, Xiao-lei Shi, Hao-zhen Ren   +4 more
doaj   +1 more source

Plasma Glutamine Concentrations in Liver Failure. [PDF]

PLoS ONE, 2016
Higher than normal plasma glutamine concentration at admission to an intensive care unit is associated with an unfavorable outcome. Very high plasma glutamine levels are sometimes seen in both acute and chronic liver failure.
Gunnel Helling, Staffan Wahlin, Marie Smedberg, Linn Pettersson, Inga Tjäder, Åke Norberg, Olav Rooyackers, Jan Wernerman   +7 more
doaj   +1 more source

Research Progress on Prognostic Prediction Models After Radical Resection of Hepatocellular Carcinoma

Xiehe Yixue Zazhi, 2023
The classical Child-Pugh classification and the model for end-stage liver disease are now widely used in clinics for postoperative assessment of liver failure and prognosis in patients with hepatocellular carcinoma (HCC) treated with radical hepatectomy.
ZHANG Yao, ZHAO Chengjun, REN Bin, DU Lei, MA Qianyuan   +4 more
doaj   +1 more source

Stimulation of OGG1 Enhances Oxidative DNA Damage Repair and Protects Against Acute Liver Failure by Acetaminophen

Advanced Science, EarlyView.
Chemical switching of OGG1 by CMM‐98 accelerates oxidative DNA damage repair and enhances hepatocyte resilience during acetaminophen‐induced acute liver injury. By promoting efficient processing of OGG1‐generated repair intermediates, CMM‐98 reduces oxidative damage, preserves cellular integrity, and protects against acute liver failure, identifying ...
Zhenjun Zhao, Rahul Upadhyay, Alice Eddershaw, Chenchen Wang, Yudong Zhao, Olov Wallner, Jinhye Ryu, Nayere Taebnia, Heather Gildie, Emma Scaletti‐Hutchinson, Jonathan R. Davies, Nicole Ziegler, Andreas Krämer, Samantha C. Robinson, Marek Varga, Karolina Singerova, Zuzanna Szaruga, Elisée Wiita, İrşil Güneş, Sheila S. David, Stefan Knapp, Aimo Kannt, Miguel de Vega, Pål Stenmark, Volker M Lauschke, Maurice Michel   +25 more
wiley   +1 more source

Mac‐2 Binding Protein Glycosylation Isomer (M2BPGi)–Based Risk Stratification Refined by Tumor Metabolic Activity in Hepatocellular Carcinoma

Annals of Gastroenterological Surgery, EarlyView.
M2BPGi reflects background liver fibrosis and hepatic functional impairment. PET SUVmax reflects tumor metabolic aggressiveness. Their combination identifies a dual‐high subgroup with the poorest recurrence‐free and overall survival. ABSTRACT Aim To evaluate the prognostic significance of preoperative Mac‐2 binding protein glycosylation isomer (M2BPGi)
Kojiro Shirabe, Junya Mita, Shinji Itoh, Takeo Toshima, Yoshiyuki Kitamura, Norifumi Iseda, Takuro Isoda, Kousei Ishigami, Tomoharu Yoshizumi   +8 more
wiley   +1 more source