Results 81 to 90 of about 2,152,009 (360)

Some notes on Goodman's marginal-free correspondence analysis [PDF]

arXiv, 2022
In his seminal paper Goodman (1996) introduced marginal-free correspondence analysis; where his principal aim was to reconcile Pearson correlation measure with Yule's association measure in the analysis of contingency tables. We show that marginal-free correspondence analysis is a particular case of correspondence analysis with prespecified weights ...
arxiv  

Raloxifene, a selective estrogen receptor modulator, is renoprotective: a post-hoc analysis [PDF]

Kidney International, 2011
Estrogens have a protective effect on kidney fibrosis in several animal models. Here, we tested the effect of raloxifene, an estrogen receptor modulator, on the change in serum creatinine or estimated glomerular filtration rate (eGFR) and incident kidney-related adverse events.
Areef Ishani, Sharon Silbiger, Joel Neugarten, Terri Blackwell, Kristine E. Ensrud, Julia H. Arnsten, Michal L. Melamed, Steven R. Cummings   +7 more
openaire   +3 more sources

Polyfunctional CD8+CD226+RUNX2hi effector T cells are diminished in advanced stages of chronic lymphocytic leukemia

Molecular Oncology, Volume 19, Issue 5, Page 1347-1370, May 2025.
CD226+CD8+ T cells express elevated levels of RUNX2, exhibit higher proliferation capacity, cytokines and cytolytic molecules expression, and migratory capacity. In contrast, CD226−CD8+ T cells display an exhausted phenotype associated with the increased expression of co‐inhibitory receptors and impaired effector functions.
Maryam Rezaeifar, Shima Shahbaz, Anthea C. Peters, Spencer B. Gibson, Shokrollah Elahi   +4 more
wiley   +1 more source

A review of univariate and multivariate multifractal analysis illustrated by the analysis of marathon runners physiological data [PDF]

arXiv, 2022
We review the central results concerning wavelet methods in multifractal analysis, which consists in analysis of the pointwise singularities of a signal, and we describe its recent extension to multivariate multifractal analysis, which deals with the joint analysis of several signals; we focus on the mathematical questions that this new techniques ...
arxiv  

TRPM4 contributes to cell death in prostate cancer tumor spheroids, and to extravasation and metastasis in a zebrafish xenograft model system

Molecular Oncology, Volume 19, Issue 5, Page 1299-1309, May 2025.
Transient receptor potential melastatin‐4 (TRPM4) is overexpressed in prostate cancer (PCa). Knockout of TRPM4 resulted in reduced PCa tumor spheroid size and decreased PCa tumor spheroid outgrowth. In addition, lack of TRPM4 increased cell death in PCa tumor spheroids.
Florian Bochen, Saurav Subedi, Federico La Manna, Sofia Jarrin, Irida Papapostolou, Marianna Kruithof‐de Julio, Christine Peinelt   +6 more
wiley   +1 more source

Polymyxin B hemoperfusion in endotoxemic septic shock patients without extreme endotoxemia: a post hoc analysis of the EUPHRATES trial

Intensive Care Medicine, 2018
PurposeThe EUPHRATES trial examined the impact of polymyxin B hemoperfusion (PMX) on mortality in patients with septic shock and endotoxemia, defined as EAA ≥ 0.60. No difference was found in 28-day all-cause mortality.
D. Klein, D. Foster, P. Walker, Sean M. Bagshaw, H. Mekonnen, Massimo Antonelli   +5 more
semanticscholar   +1 more source

Higher Postinduction Infliximab Concentrations Are Associated With Improved Clinical Outcomes in Fistulizing Crohn's Disease: An ACCENT-II Post Hoc Analysis

American Journal of Gastroenterology, 2020
INTRODUCTION: There are only limited data regarding the role of therapeutic drug monitoring in fistulizing Crohn's disease (CD). We investigated the association between both induction and maintenance serum infliximab concentrations and favorable ...
K. Papamichael, N. Vande Casteele, J. Jeyarajah, V. Jairath, M. Osterman, A. Cheifetz   +5 more
semanticscholar   +1 more source

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

Molecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi, Kazunori Mori, Hidetsugu Nakagawa, Momoko Uchida, Fumihiro Ishikawa, Motoko Shibanuma   +5 more
wiley   +1 more source

Principal Moment Analysis [PDF]

arXiv, 2020
Principal Moment Analysis is a method designed for dimension reduction, analysis and visualization of high dimensional multivariate data. It generalizes Principal Component Analysis and allows for significant statistical modeling flexibility, when approximating an unknown underlying probability distribution, by enabling direct analysis of general ...
arxiv  

Cap assisted colonoscopy for the detection of serrated polyps: a post-hoc analysis [PDF]

BMC Gastroenterology, 2015
Colonoscopy offers limited protection against right-sided colon cancer, a significant proportion of which arise from the serrated pathway of carcinogenesis. The aim of this study was to compare cap-assisted colonoscopy and standard high-definition white light colonoscopy regarding serrated polyps' detection.Post hoc analysis was performed of a ...
Sachin Wani, Amit Rastogi, Ajay Bansal, Prateek Sharma, Fadi Rzouq, Neil Gupta   +5 more
openaire   +3 more sources