Results 51 to 60 of about 269,720 (245)

A Quality Improvement Initiative To Reduce Invasive Candidiasis In Extremely Low Birth Weight Neonates

Pakistan Armed Forces Medical Journal
Objective: To evaluate the impact of a quality improvement (QI) initiative, which included a Fluconazole prophylaxis protocol and provider education on neonatal Candidiasis. Study Design: Retrospective longitudinal study. Place and Duration of Study:
Syed Muzaffar Saleem, Uswa Jiwani, Ali Shabbir Hussain, Manoj Kumar, Radhika Suresh Kumar, Shabina Ariff   +5 more
doaj   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Standardized nutritional screening and assessment for nasopharyngeal cancer patients: an evidence-based implementation project

BMC Nursing
Introduction Radiotherapy for nasopharyngeal cancer (NPC) frequently induces malnutrition, which is a serious complication that adversely affects patients’ quality of life and prognosis.
Wenwen Cai, Rufei Yang, Chao Tang, Yueyao Cao, Jing Li, Jinmei Huang, Yalan Song   +6 more
doaj   +1 more source

Bridging the Gap between Theory and Practice; the Active Role of Inpatient Pharmacists in Therapeutic Drug Monitoring

Pharmacy, 2019
Many hospitals face barriers in the implementation of TDM services, this study aimed to evaluate a pharmacist-led TDM service to optimize patients’ outcomes.
Abrar F Alhameed, Sara Al Khansa, Hani Hasan, Sherine Ismail, Mohammed Aseeri   +4 more
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Feasibility and acceptability of using the BabySaver resuscitation platform and NeoBeat together for neonatal resuscitation in a low-resource setting: A pre-post implementation study.

PLoS ONE
BackgroundBabySaver and NeoBeat devices have the potential to enable bedside neonatal resuscitation, with an intact cord in the presence of the mother. We assessed the feasibility and acceptability of using them together for neonatal resuscitation in a ...
Milton W Musaba, Ritah Nantale, David Mukunya, Julius N Wandabwa, Kathy Burgoine, Nicolas J Pejovic, Benjamin A Kamala, Agnes Napyo, Kenneth Mugabe, Brendah Nambozo, Faith Oguttu, John Stephen Obbo, Thorkild Tylleskar, Andrew D Weeks   +13 more
doaj   +1 more source

An implementation science approach for developing and implementing a dietitian-led model of care for gestational diabetes: a pre-post study

BMC Pregnancy and Childbirth, 2020
Background There is strong evidence that women with gestational diabetes mellitus (GDM) who receive a minimum of three appointments with a dietitian may require medication less often.
Nina MELONCELLI, Adrian BARNETT, Susan de JERSEY   +2 more
doaj   +1 more source

A tale of success or complete disaster? : A case study of the post-implementation phase of a new ERP system

, 2023
Enterprise Resource Planning (ERP) systems are considered to be the backbone of many organizations, however, many implemented ERP systems do not live up to the expected potential of organizations. The pre-implementation and implementation phases of ERP projects have received a fair amount of attention in previous literature, but the post ...
Häggblad, Alva, Sundström, Johan
openaire   +1 more source