Results 41 to 50 of about 6,606,497 (285)

Digital Therapeutics in Perspective: From Regulatory Challenges to Post-Marketing Surveillance

Frontiers in Drug Safety and Regulation, 2022
Digital therapeutics (DTx) are innovative therapeutic interventions, in which the therapeutic activity is carried out by algorithms and software. They represent a new opportunity especially for the treatment of chronic pathologies associated with ...
Salvatore Crisafulli, Eugenio Santoro, Giuseppe Recchia, Giuseppe Recchia, Gianluca Trifirò   +4 more
doaj   +1 more source

Multimodal Imaging of Hypoxia, Metabolism and pH in Feline Sarcoma Using Hyperpolarized 13C MRI and PET

Advanced Science, EarlyView.
This work presents a clinically deployable simultaneous PET/MRI workflow which integrates hyperpolarized 13C imaging of metabolism and extracellular pH with [18F]FMISO PET to characterize hypoxia, acidosis, and metabolic reprogramming in feline sarcoma.
Martin Grashei, Tanja Groll, Stephanie Kahl, Silke Baer, Elisabeth Bliemsrieder, Frits H. A. van Heijster, Andre Wendlinger, Pascal Wodtke, Jorge Cabello, Susan Notohamiprodjo, Christian Lohrmann, Markus Schwaiger, Wolfgang A. Weber, Katja Steiger, Andrea Meyer‐Lindenberg, Johannes Hirschberger, Christine Baumgartner, Franz Schilling   +17 more
wiley   +1 more source

Analyzing the U.S. Post-marketing safety surveillance of COVID-19 vaccines

Saudi Pharmaceutical Journal, 2022
Introduction: Since December 2020, three COVID-19 vaccines have been authorized in the United States (U.S.) and were proceeded by large immunization programs. The aim of this study was to characterize the U.S.
Omar M. Albalawi, Maha I. Alomran, Ghada M. Alsagri, Turki A. Althunian, Thamir M. Alshammari   +4 more
doaj   +1 more source

Low‐Intensity Ultrasound‐Triggered Microbubble Cavitation Attenuates Diabetic Kidney Injury Partially by Reversing Endothelial Dysfunction

Advanced Science, EarlyView.
Non‐invasive low‐intensity pulsed ultrasound ‐triggered cavitation of clinically approved diagnostic‐grade microbubbles delivers favorable mechanical stimuli to renal microvasculature. This intervention restores renal microvascular homeostasis, alleviates DKD‐associated histological and functional damage, and suppresses inflammatory and fibrotic ...
Yubo Lai, Liang Zhang, Wenxin Tao, Jieyuan An, Lantian Wang, Zhaoyou Liu, Guodong Yang, Pengying Wu, Lijun Yuan   +8 more
wiley   +1 more source

Editorial: Surveillance from a Post-Communist Perspective

, 2018
This special issue is the result of a research initiative that began in 2013, just before the annexation of Crimea by Russia. We, the guest editors, together with Paweł Waszkiewicz at the University in Warsaw, wanted to fill a gap in research on ...
Svenonius, Ola, Björklund, Fredrika
core   +1 more source

Case Report: ANCA-Associated Vasculitis Presenting With Rhabdomyolysis and Pauci-Immune Crescentic Glomerulonephritis After Pfizer-BioNTech COVID-19 mRNA Vaccination

Frontiers in Immunology, 2021
As the coronavirus disease 2019 (COVID-19) pandemic is ongoing and new variants of severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) are emerging, there is an urgent need for COVID-19 vaccines to control disease outbreaks by herd immunity.
Samy Hakroush, Björn Tampe
doaj   +1 more source

Current Standards of Monitoring Models in Healthcare Settings

Advanced Intelligent Discovery, EarlyView.
AI/ML‐enabled medical devices are entering clinical practice faster than monitoring standards mature. This review highlights gaps in postmarket surveillance, limited use of predetermined change‐control plans, and the need for ongoing performance tracking, drift detection, explainability, and workflow‐aware governance to support safer, more reliable ...
Alan Kay, Daljit Takher, Wenting Liu, Emily Wittrup, Gilbert S. Omenn, Kayvan Najarian   +5 more
wiley   +1 more source

Causal analysis of trade loss from pathogens: A global study of foot and mouth disease impacts on meat exports

American Journal of Agricultural Economics, EarlyView.
Abstract Our general interest is in global trade loss from livestock pathogens, specifically exports. We adopt a causal inference approach that considers animal disease outbreaks over time as non‐staggered binary treatments with the potential for switching in (infection) and out of treatment (recovery) within the sample period. The outcome evolution of
Mohammad Maksudur Rahman, Thomas L. Marsh   +1 more
wiley   +1 more source

Impact of Post Marketing Surveillance on Falsified Medicine in Nigeria.

, 2021
The thesis aims to evaluate the impacts of post marketing surveillance on falsified medicines among healthcare professionals (medical doctors and pharmacists) and consumers in Nigeria by conducting a questionnaire-based survey for quantitative research ...
Mgboko, Chukwudi Anthony
core   +1 more source

Surveillance, Repression and the Welfare State: Aspects of Continuity and Discontinuity in post-Fascist Italy

, 2013
This paper seeks to explore political, cultural, legal and socio-economic legacies of the Fascist regime (1922-1943) in Italy. With the fall of the regime, in fact, the overall surveillance apparatus did not fade away.
Agnoletto, Stefano, Fonio, Chiara
core   +1 more source