Results 201 to 210 of about 10,520,983 (276)

A Pilot Mixed Methods Reimagination of Rural Critical Access Hospital Design Process. [PDF]

HERD
Johnson EA, Alexander-Ruff J, McCrory B.
europepmc   +1 more source

Purpurin Alleviates Chemotherapy‐Induced Thrombocytopenia Through Estrogen Receptor α Dependent Phosphoinositide 3‐Kinase/Protein Kinase B Signalling

Phytotherapy Research, EarlyView.
Schematic overview of the in vitro and in vivo evaluation of purpurin in promoting MK maturation and platelet production, through ESR1/PI3K/AKT. ABSTRACT Chemotherapy‐induced thrombocytopenia (CIT) increases bleeding risk and compromises chemotherapy delivery.
Xiaolin Gan, Xinle Wang, Lu Hao, Xiaoqin Tang, Zhixuan Liu, Long Wang, Xiang Xie, Xiang Li, Chunling Zhao, Yan Li, Xinwu Huang, Yuanzhi Liu, Jianming Wu   +12 more
wiley   +1 more source

Impact of Rural Trauma Team Development Education on Prehospital Time, Referral-to-Dispatch Interval, and Neurological and Musculoskeletal Injury Outcomes: Cluster Randomized Controlled Trial. [PDF]

JMIR Hum Factors
Lule H, Mugerwa M, Abio A, Oguttu B, Kakeeto A, Walsh FJ, Lekuya HM, Ssebuufu R, Kyamanywa P, Deckert A, Bärnighausen T, Posti JP, Wilson ML.   +12 more
europepmc   +1 more source

Notoginsenoside R2 Antagonizes Renal Interstitial Fibrosis by Regulating Fatty Acid Oxidation via the CASP2/ALDH3A1 Axis

Phytotherapy Research, EarlyView.
Proposed mechanism by which notoginsenoside R2 (NGR2) attenuates renal interstitial fibrosis. In injured renal tubular epithelial cells, CASP2 downregulation and enhanced ubiquitin‐dependent degradation of ALDH3A1 disrupt mitochondria‐associated endoplasmic reticulum membranes (MAMs) and impair fatty acid oxidation (FAO), leading to lipid accumulation ...
Guanting Chen, Tao Li, Zhenzhen Wang, Hao Zhao, Xiaoxia Xun, Yijiao Wang, Shiyuan Jiang, Qing Zhang, Weiwei Sun, Kang Yang, Yaoxian Wang   +10 more
wiley   +1 more source

Dihydroartemisinin Engages NQO1 and Promotes Ferroptosis‐Related Oxidative Stress in Non‐Small Cell Lung Cancer

Phytotherapy Research, EarlyView.
Dihydroartemisinin Engages NQO1 and Promotes Ferroptosis‐Related Oxidative Stress in Non‐Small Cell Lung Cancer. ABSTRACT Dihydroartemisinin (DHA), a bioactive derivative of Artemisia annua L. (AAL), has shown antitumor activity in several malignancies, including non‐small cell lung cancer (NSCLC).
Xiuli Guo, Gan Tao, Mini Zhang, Linzhi Han, Sisi Yan, Chunsheng Wang, Jianguo Zhang, Xiaowan Guo, Kehua Hu, Yan Gong, Qiuji Wu, Conghua Xie   +11 more
wiley   +1 more source

Testing Times: A Structure/Agency Perspective on Becoming a Science Teacher in a Competitive, Exam‐Based Teacher Selection System

Science Education, EarlyView.
ABSTRACT While extensive research exists on science teacher shortages, less attention has been directed toward countries facing the opposite challenge: an oversupply of science teachers. This study examines the experiences of prospective science teachers in South Korea, where passing a high‐stakes, annual competitive examination is a prerequisite for ...
Wonyong Park, Heesoo Ha
wiley   +1 more source

Evaluation of the sedative-motor effects of novel GABAkine imidazodiazepines using quantitative observation techniques in rhesus monkeys. [PDF]

J Psychopharmacol
Sharmin D, Rüedi-Bettschen D, Berro LF, Cook JE, Reeves-Darby JA, Pareek T, Mian MY, Rashid F, Golani L, Moreira-Junior EDC, Platt DM, Cook JM, Rowlett JK.   +12 more
europepmc   +1 more source

Strategies to Advance the Energy Efficiency, Water Efficiency, and Indoor Environmental Quality in New Zealand's Sustainable Building Designs and Practices

Sustainable Development, EarlyView.
ABSTRACT Sustainable Building Designs and Practices (SBDPs) are increasingly important for reducing environmental impacts, conserving resources, and improving occupant well‐being. This study examines New Zealand building professionals' perceptions of the integration and performance of energy efficiency (EE), water efficiency (WE), and Indoor ...
Tharaya Poorisat, Itohan Esther Aigwi, Dat Tien Doan, Ali GhaffarianHoseini   +3 more
wiley   +1 more source