Results 221 to 230 of about 10,520,983 (276)

Epidermal and ECM Damage Following Pinch Injury Restricts Dendrite Regeneration in <i>Drosophila</i>. [PDF]

eNeuro
Brantley MA, Pandiyan A, Danh AC, Prange SE, Rimicci DS, Thompson-Peer KL.   +5 more
europepmc   +1 more source

Challenges in Gene‐Directed Therapies for Rare Neurodevelopmental Disorders Using HNRNPU as an Exemplar

Clinical Genetics, EarlyView.
Beyond diagnosing rare neurodevelopmental disorders like HNRNPU‐RNDD, developing gene‐directed therapies requires overcoming complex hurdles, including spatial, developmental, and cell‐type constraints. Addressing these requires understanding the molecular effects of dosage and chromatin dynamics to deliver precise, effective treatments.
Daniel Aiyedun, Susan F. Rogers, Doaa M. Taha, Meena Balasubramanian   +3 more
wiley   +1 more source

Qualitative analysis as a tool for reducing investment risks in post-mining areas located in urban structures. [PDF]

PLoS One
Chećko A, Jelonek Z, Jelonek I.
europepmc   +1 more source

Chromatin Modifications Orchestrate DNA Repair Pathway Choice: Epigenetics Strategies for Enhancing CRISPR–Cas9‐Mediated Knock‐In Efficiency

Cell Proliferation, EarlyView.
Histone modifications at CRISPR–Cas9‐induced DNA double‐strand breaks shape chromatin states and regulate DNA repair pathway choice. Transient epigenetic modulation may provide a promising strategy to enhance CRISPR–Cas9‐mediated gene knock‐in.
Xin Chen, Shan Qin, Ce Yang, Zhiyao Xing, Chong Liu, Xingchen Zhang, Xi Wu, Xueren Li, Yanhua Gong, Zichuan Liu   +9 more
wiley   +1 more source

Exploring Smart Furniture: A Systematic Review of Integrated Technologies, Functionalities, and Applications. [PDF]

Sensors (Basel)
Mimoso I, Brites-Pereira M, Alcântara L, Morgado MI, Morgado G, Saavedra I, Muñoz FJM, Louceiro J, Costa E.   +8 more
europepmc   +1 more source

MD‐1 Deficiency Mitigates Atherosclerosis by Inhibiting NLRP3 Inflammasome Activation via cGAS‐STING Dependent Pathway in Macrophages

Cell Proliferation, EarlyView.
MD‐1 is induced and activated in macrophages. The activated MD‐1 subsequently promotes the cGAS‐STING‐TBK1‐IRF3 signalling pathway to activate the NLRP3 inflammasome, and subsequently increases pro‐inflammatory macrophage polarisation and decreases plaque stability to accelerate the development of atherosclerosis.
Fang Zhao, Zhili Jin, Zhiwei Cai, Quan Zhang, Tao He, Xiangjie Kong, Ming Chen, Zhibing Lu, Xiaorong Hu, Wen‐Lin Cheng   +9 more
wiley   +1 more source

Assessing the restorative environment of pocket parks in old urban districts of Chinese cities in the context of healthy aging. [PDF]

Front Public Health
Hu D, Lu Y, Guo Y, Wu Y, Shen G, Ma L, Li L.   +6 more
europepmc   +1 more source

Evaluation of a Google Classroom Biochemistry Course for Undergraduate Dentistry Students

European Journal of Dental Education, EarlyView.
ABSTRACT Introduction Instructing students for biochemistry courses is consistently a challenge. It is important to employ various didactic strategies to improve understanding of the chemical processes that occur in living organisms and to identify basic tools for experimental teaching.
Marisol Rosas‐Martínez, Jhon Helibert‐Torres, Itzel Juárez‐Ramos, Arturo Emiliano Meza‐Ramírez, Gloria Gutiérrez‐Venegas   +4 more
wiley   +1 more source

Naturally Derived Psilocybin for Therapeutic Use: A Six-Criterion Framework for Evidence, Safety, and Benefit-Risk Considerations in Policy and Clinical Development. [PDF]

Biomolecules
Enriquez-Geppert S, Bevers L, Rosander A, Fodran P, Polito V.   +4 more
europepmc   +1 more source