Results 211 to 220 of about 10,520,983 (276)

Macroscopic Convective Fluid Flows Arising From Binding of Ions and Small Molecules to Proteins

open access: yesSmall, EarlyView.
The interaction of ions or small molecules with proteins causes convective flows due to the displacement of water from the hydration shell. As shown, the replacement of the nickel ion removed from urease by EDTA pre‐treatment results in binding‐induced convective fluid flow.
Shanid Babu Shrestha   +4 more
wiley   +1 more source

Screening of Brazilian Isolated Yeasts Reveals Multiple Potential Chassis for Industrial Biotechnology

open access: yesYeast, EarlyView.
Harnessing Brazilian microbial diversity, comprehensive phenotypic screening of 79 yeast isolates identified non‐conventional strains with superior multi‐stress tolerance and metabolic versatility compared to S. cerevisiae under industrially relevant conditions.
Giovanna R. Maklouf   +10 more
wiley   +1 more source

CBX4 stabilizes NEUROD1 through SUMO-ubiquitin crosstalk to delay β-cell senescence. [PDF]

open access: yesNat Commun
Su L   +16 more
europepmc   +1 more source

Hormone Replacement Therapy Uptake and Discontinuation Trends From 1996‐2023: An Observational Study of the Welsh Population

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To analyse prescribing trends for oral and transdermal hormone replacement therapy (HRT) in Wales from 1996 to 2023, including predictors of discontinuation within one year of initiation. Design Observational study using the Secure Anonymised Information Linkage (SAIL) databank.
Robin Andrews   +3 more
wiley   +1 more source

Museomics Deciphers the Phylogeographic Differentiation and Conservation Status of a Montane Pheasant

open access: yesIntegrative Zoology, EarlyView.
Museum specimens provide a rich source of historical DNA, enabling insights into phylogenetic relationships and demographic history of the endangered Koklass Pheasant. Our findings uncovered a previously unrecognized population in Guizhou province and highlighted elevated extinction risk in populations from Anhui province and Southern China, informing ...
Zhiyong Jiang   +9 more
wiley   +1 more source

Androgens Modulate Tumor–Immune Interactions in Testicular Germ Cell Tumors

open access: yesAndrology, EarlyView.
ABSTRACT Background The majority of testicular germ cell tumors (TGCT) are derived from the germ cell neoplasia in situ and arise after puberty in the local presence of high levels of testosterone. The seminoma subtype features a rich inflammatory infiltrate which impacts tumor progression but the role of testosterone in shaping tumor–immune ...
Ida Hamann   +6 more
wiley   +1 more source

Dataset of an operating education modular building for simulation and artificial intelligence. [PDF]

open access: yesData Brief
Cormier PA   +5 more
europepmc   +1 more source

Peanut‐Specific IgG4 mAbs Promote Regulatory Immune Responses Ex Vivo and Improve Oral Immunotherapy in Mice

open access: yesClinical &Experimental Allergy, EarlyView.
Allergen‐specific IgG4 mAbs were shown to block facilitated IgE binding to B cells and redirect allergens towards myeloid APC, leading to increased IL‐10 production in vitro. In combination with oral AIT, the mAbs inhibited mast cell activation and sustained allergen‐specific IgG4 levels in an in vivo model of peanut allergy. ABSTRACT Background Peanut
Pascal Gasser   +12 more
wiley   +1 more source

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