Results 191 to 200 of about 90,964 (263)

A Gap Analysis of Deep Brain Stimulation for Childhood‐Onset Movement Disorders

open access: yesMovement Disorders, EarlyView.
Abstract Background Deep brain stimulation (DBS) is an established and increasingly utilized therapy for childhood‐onset movement disorders. However, pediatric DBS poses unique challenges that are not adequately addressed by adult‐derived paradigms. Objective To identify key gaps in the current use of DBS in childhood‐onset movement disorders and to ...
Daniela Munoz‐Chesta   +6 more
wiley   +1 more source

Apathy in Lewy Body Disorders: A Position Paper

open access: yesMovement Disorders, EarlyView.
Abstract Apathy is one of the most prevalent and disabling non‐motor symptoms in Parkinson's disease (PD) and dementia with Lewy bodies (DLB), collectively referred to as Lewy body disorders (LBDs). It is associated with reduced quality of life, accelerated cognitive decline, increased caregiver burden, and poorer functional outcomes, yet remains ...
Jaime Kulisevsky   +12 more
wiley   +1 more source

Timing of Deep Brain Stimulation and Cognitive Trajectories in GBA1‐Associated Parkinson's Disease

open access: yesMovement Disorders, EarlyView.
Abstract Background Individuals with Parkinson's disease (PD) carrying GBA1 variants often develop advanced motor complications that prompt evaluation for deep brain stimulation (DBS). However, concerns about accelerated cognitive decline after DBS in GBA1 carriers complicate clinical decision making.
Evridiki Asimakidou   +61 more
wiley   +1 more source

Whole‐Brain Cerebral Microvascular Pulsatility Imaging Using Dynamic pCASL MRI With Segmented Stack‐of‐Stars Golden‐Angle Radial Acquisition

open access: yesMagnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To develop an efficient dynamic pseudo‐continuous arterial spin labeling (pCASL) MRI technique for whole‐brain microvascular flow pulsatility imaging. Methods The proposed technique combines pCASL with a segmented stack‐of‐stars golden‐angle radial acquisition.
Tianrui Zhao   +5 more
wiley   +1 more source

Protecting the brain from post-stroke cognitive impairment and dementia with multimodal exercise training: study protocol for a Bayesian adaptive trial (PROTECT). [PDF]

open access: yesBMJ Open
Moncion K   +18 more
europepmc   +1 more source

Urinary Incontinence and Risk of All‐Cause Mortality: A Systematic Review and Meta‐Analysis of Observational Studies

open access: yesNeurourology and Urodynamics, EarlyView.
ABSTRACT Aims Urinary incontinence (UI) is a prevalent condition among adults and imposes a substantial societal burden, yet its association with all‐cause mortality remains uncertain. This study systematically reviewed and quantified the association between UI and mortality risk.
Yanyan Zhou   +6 more
wiley   +1 more source

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