Results 51 to 60 of about 4,772,746 (271)

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Algeria as Postcolony? Rethinking the Colonial Legacy of Post-Structuralism

open access: yesJournal of French and Francophone Philosophy, 2011
While there is little doubt that Algeria was of enormous importance to the theoretical output that is often recognized as French, here I would like to ask: what is at stake in re-inscribing these French intellectuals as postcolonial? In what ways did the
Muriam Haleh Davis
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Language, Metaphor, Truth: The Role of Metaphor in the Development of Post-structuralism, based on Derrida's Ideas [PDF]

open access: yesLiterary Arts, 2017
Poststructuralists, especially Derrida rely on processes and mechanisms such as deferment, trace and otherness to deal with the criticism of binary oppositions and metaphysics-based approaches.
Fardin Hosseinpanahi   +1 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

The Subject of Feminism and Post-Structuralism

open access: yesRevista Estudos Feministas, 2005
This paper approaches the criticism of post-structural feminist theories as well as the theories of the universal subject, rejecting the notions of the essential identity of gender.
Silvana Aparecida Mariano
doaj  

Lo strutturalismo scientifico. Matematica, Fisica e Biologia nell’ottica piagetiana

open access: yesRivista Internazionale di Filosofia e Psicologia, 2019
Piagetian structuralism, notably a genetic epistemological perspective on mathematics, physics and biology, represents a unique and fruitful articulation of the heterogeneous structuralist movement.
Francesco Crapanzano
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

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