Results 81 to 90 of about 4,772,746 (271)
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
BORGES, CLARICE, AND THE DEVELOPMENT OF LATIN AMERICA’S “NEW NARRATIVE”
Revista Brasileira de Literatura Comparada, 2022 Latin American “New Narrative” is commonly associated with avant-garde writing such as that practiced by Spanish American writers like Borges, Rulfo, Cortázar, García Marquez, among others. Nevertheless, we can outline a different history of experimental
Earl E. Fitz
doaj
From structuralism to post-structuralism: Derrida's critique of structuralism as deconstruction
, 2020 In the social sciences, many theories have been put forward for the explanation and understanding of social reality. Each theory reveals several possibilities for the purpose in question, as well as many dead ends or problems.
Keskin, İbrahim
core +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Discourse theories and post-structuralism
, 2012 Discourse theories and post ...
Simon Tormey (17367472)
core
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
ADVERTISING COMMUNICATION IN THE DISCOURSE OF NEOMARXISTS, STRUCTURALISTS AND POST-STRUCTURES
Juvenis Scientia, 2019 The article discusses the main approaches to the study of advertising communication, expressed in the works of philosophical schools of the XX century.
Kuzmin V.V.
doaj +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source