Results 211 to 220 of about 571,207 (361)

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

m6A-modified LINC02418 induces transcriptional and post-transcriptional modification of CTNNB1 via interacting with YBX1 and IGF2BP1 in colorectal cancer. [PDF]

Cell Death Discov
Zhang H, Han Y, Wu C, Wang S, Chen M, Xu Q, Wei H, Zhou X, Wang G.   +8 more
europepmc   +1 more source

Dengue virus infection alters post-transcriptional modification of microRNAs in the mosquito vector Aedes aegypti. [PDF]

Sci Rep, 2015
Etebari K, Osei-Amo S, Blomberg SP, Asgari S.   +3 more
europepmc   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Search for differences in post-transcriptional modification patterns of mitochondrial DNA-encoded wild-type and mutant human tRNALys and tRNALeu(UUR).

Nucleic Acids Research, 1999
M. Helm, C. Florentz, A. Chomyn, G. Attardi   +3 more
semanticscholar   +1 more source

Defective post-transcriptional modification of tRNA disrupts mitochondrial homeostasis in Leber's hereditary optic neuropathy. [PDF]

J Biol Chem
Zhang J, Li W, Liu Z, Chen Y, Wei X, Peng L, Xu M, Ji Y.   +7 more
europepmc   +1 more source

Post-transcriptional modification in archaeal tRNAs: identities and phylogenetic relations of nucleotides from mesophilic and hyperthermophilic Methanococcales.

Nucleic Acids Research, 2001
J. McCloskey, D. Graham, S. Zhou, P. F. Crain, M. Ibba, J. Konisky, D. Söll, G. Olsen   +7 more
semanticscholar   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

MicroRNA chemical modifications in post-transcriptional gene silencing and human diseases

Amin Alaei, Pavan Kumar Kakumani
openalex   +1 more source

Orchestrated positioning of post-transcriptional modifications at the branch point recognition region of U2 snRNA [PDF]

, 2017
Svetlana Deryusheva, Joseph G. Gall
openalex   +1 more source