Results 241 to 250 of about 1,190,541 (329)

Understanding and Targeting HBV Transcription and Post-Transcriptional Regulation. [PDF]

Viruses
Fletcher SP, Beran RK.
europepmc   +1 more source

Injectable Dual‐Network Hydrogel System for Osteochondral Repair Combining Immunomodulation, Mechanical Adaptability, and Enhanced Tissue Integration

Advanced Functional Materials, EarlyView.
A UV‐triggered injectable dual‐network hydrogel is reported as the first application of bletilla striata polysaccharide (BSP) in osteochondral repair. By integrating methacrylamide‐modified BSP and nitrobenzaldehyde‐functionalized hyaluronic acid, the system achieves immunomodulation, mechanical reinforcement, and dynamic tissue adhesion, thereby ...
Jiaming Cui, Feifei Zhou, Yuan Luo, Tao Ouyang, Huiwu Zhang, Songmiao Cheng, Qiang Li, Xu Jiang, Yingying Yu, Yicheng Wang, Hong Ming   +10 more
wiley   +1 more source

RVINN: a flexible modeling for inferring dynamic transcriptional and post-transcriptional regulation using physics-informed neural networks. [PDF]

Bioinformatics
Muto O, Guo Z, Yamaguchi R.
europepmc   +1 more source

Circadian Proteomic Analysis Uncovers Mechanisms of Post-Transcriptional Regulation in Metabolic Pathways.

Cell Systems, 2018
J. Hurley, Meaghan S. Jankowski, H. De los Santos, Alexander M. Crowell, Samuel B. Fordyce, Jeremy D. Zucker, Neeraj Kumar, S. Purvine, E. Robinson, Anil K Shukla, Erika M. Zink, W. Cannon, S. Baker, J. Loros, J. Dunlap   +14 more
semanticscholar   +1 more source

Biointerface Membranes Orchestrating Site‐Specific Osteoimmunomodulatory and Antibacterial Effects for Enhanced Osseous Regeneration in Periodontal Therapy

Advanced Functional Materials, EarlyView.
Here, a biointerface membrane engineered with site‐specific interfacial properties is developed. During implantation between gingival and bone defect, the membrane creates a pro‐osteogenic microenvironment, precisely modulates cellular activities at each biointerface, and facilitates the orchestration of complex healing events, ultimately leading to ...
Yuwei Zhu, Tingting Wang, Jing Zhu, Bingtian Zhao, Bingyang Dai, Xiaoyue Zhang, Wei Liu, Cheng Yang, Cheng Dong, Ren Liu, Lei Zhao, Jun Wang, Peilei Shi, To Ngai   +13 more
wiley   +1 more source

ERH regulates type II interferon immune signaling through post-transcriptional regulation of JAK2 mRNA. [PDF]

Nucleic Acids Res
Soderholm A, Vunjak M, de Almeida M, Popitsch N, Podvalnaya N, Araguas-Rodriguez P, Scinicariello S, Nischwitz E, Butter F, Ketting RF, Ameres SL, Müller-McNicoll M, Zuber J, Versteeg GA.   +13 more
europepmc   +1 more source

MagPiezo: A Magnetogenetic Platform for Remote Activation of Endogenous Piezo1 Channels in Endothelial Cells

Advanced Functional Materials, EarlyView.
MagPiezo enables wireless activation of endogenous Piezo1 channels without genetic modification using 19 nm magnetic nanoparticles and low‐intensity magnetic fields. It generates torque forces at the piconewton scale to trigger mechanotransduction in endothelial cells, standing as a novel platform to interrogate and manipulate Piezo1 activity in vitro.
Susel Del Sol‐Fernández, Mariarosaria De Simone, Yilian Fernández‐Afonso, Daniel Garcia‐Gonzalez, Pablo Martínez‐Vicente, Thomas van Zanten, Raluca M. Fratila, Maria Moros   +7 more
wiley   +1 more source

Widespread impact of transposable elements on the evolution of post-transcriptional regulation in the cotton genus Gossypium. [PDF]

Genome Biol
Tian X, Wang R, Liu Z, Lu S, Chen X, Zhang Z, Liu F, Li H, Zhang X, Wang M.   +9 more
europepmc   +1 more source

Post-transcriptional gene regulation by mRNA modifications

Nature reviews. Molecular cell biology, 2016
B. Zhao, I. A. Roundtree, Chuan He
semanticscholar   +1 more source

Poly(lactic‐co‐glycolic acid) Nanoparticles for IL‐12 Self‐Amplifying RNA Delivery in Glioblastoma Models

Advanced Functional Materials, EarlyView.
xxxx. ABSTRACT Glioblastoma (GBM) remains one of the most lethal brain cancers, with median survival rarely exceeding 15 months after diagnosis. Interleukin‐12 (IL‐12) is a potent immunostimulatory cytokine capable of reshaping the tumor microenvironment (TME), yet its clinical translation is hindered by systemic toxicity and short half‐life. RNA‐based
Fatima Hameedat, Johan Sebastian Lopez‐Parra, Willem M. H. Hoogaars, Emma Dijkstra, Cynthia Huang, Irafasha C. Casmil, Anna K. Blakney, Peter Olinga, Barbara Rothen‐Rutishauser, Hélder A. Santos, Alke Petri‐Fink, Flávia Sousa   +11 more
wiley   +1 more source