The role of CEMIP in cancers and its transcriptional and post-transcriptional regulation. [PDF]
Guo S+5 more
europepmc +1 more source
Most in vitro cancer models lack cellular diversity, functional complexity, and clinical relevance. This work highlights the generation of an innovative dynamic tetraculture with autologous patient‐derived cells within a vascularized tumor‐on‐chip, as well as the recapitulation of endothelial anergy features induced by the tumor microenvironment ...
Christine Lansche+16 more
wiley +1 more source
Post-transcriptional regulation shapes the transcriptome of quiescent budding yeast. [PDF]
Greenlaw AC, Alavattam KG, Tsukiyama T.
europepmc +1 more source
Liquid Crystalline Networks Hamper the Malignancy of Cancer Cells
Liquid Crystalline Networks are used as scaffolds for the growth of A375 melanoma cells demonstrating to affect their malignancy. Indeed, only by contact, these materials reduces cell proliferation and colony formation capacity, while increasing the number of senescent cells and promoting the mesenchymal to epithelial transition.
Daniele Martella+9 more
wiley +1 more source
Post-transcriptional regulation of DEAD-box RNA helicases in hematopoietic malignancies. [PDF]
Fan J, Li Z, Pei L, Hou Y.
europepmc +1 more source
Engineering Assembloids to Mimic Graft‐Host Skeletal Muscle Interaction
This study develops a graft‐host skeletal muscle assembloid model combining neuromuscular organoids with tissue‐engineered constructs. Pre‐seeding decellularized muscles with myogenic cells enhances cell migration and axon invasion from the organoid. The model exhibits regenerative capacity following acute damage, advancing the understanding of human ...
Lucia Rossi+13 more
wiley +1 more source
YTHDF1 promotes gallbladder cancer progression via post-transcriptional regulation of the m6A/UHRF1 axis. [PDF]
Chen J+8 more
europepmc +1 more source
Engineering the Future of Restorative Clinical Peripheral Nerve Surgery
What if damaged nerves could regenerate more effectively? This review unveils cutting‐edge strategies to restore nerve function, from biomaterial scaffolds and bioactive molecules to living engineered tissues. By accelerating axonal regrowth, preserving Schwann cells, and enhancing connectivity, these approaches are reshaping nerve repair—offering new ...
Justin C. Burrell+5 more
wiley +1 more source
Transcriptional and post-transcriptional regulation of CARMN and its anti-tumor function in cervical cancer through autophagic flux blockade and MAPK cascade inhibition. [PDF]
Zhang X+21 more
europepmc +1 more source
Post-transcriptional small RNA pathways in plants: mechanisms and regulations
Hervé Vaucheret
openalex +1 more source