Results 81 to 90 of about 694,082 (344)

Spot‐14 and its paralog Spot‐14R regulate expression of metabolic and thermogenic pathway genes in murine brown and beige adipocytes

open access: yesFEBS Letters, EarlyView.
Spot‐14 and Spot‐14R play distinct roles in regulating metabolism in brown and beige adipocytes. While both influence lipid and glucose pathways, Spot‐14 uniquely controls thermogenic gene expression. This dual regulation balances energy storage and heat production, highlighting potential therapeutic targets for obesity and metabolic disorders. Spot 14
Lidia Itzel Castro‐Rodríguez   +3 more
wiley   +1 more source

From the proteomic point of view: Integration of adaptive changes to iron deficiency in plants

open access: yesCurrent Plant Biology, 2016
Knowledge about the proteomic adaptations to iron deficiency in plants may contribute to find possible new research targets in order to generate crop plants that are more tolerant to iron deficiency, to increase the iron content or to enhance the ...
Hans-Jörg Mai, Petra Bauer
doaj   +1 more source

STAT3 expression is reduced in cardiac pericytes in HFpEF and its loss reduces cellular adhesion and induces pericyte senescence

open access: yesFEBS Letters, EarlyView.
Heart failure with preserved ejection fraction (HFpEF) accounts for half of the heart failure cases. It is characterised by microvascular dysfunction, associated with reduced pericyte coverage and diminished STAT3 expression in pericytes. Loss of STAT3 impairs pericyte adhesion, promotes senescence, and activates a pro‐fibrotic gene program.
Leah Rebecca Vanicek   +15 more
wiley   +1 more source

Regulation of gene expression by small non‐coding RNAs: a quantitative view

open access: yesMolecular Systems Biology, 2007
The importance of post‐transcriptional regulation by small non‐coding RNAs has recently been recognized in both pro‐ and eukaryotes. Small RNAs (sRNAs) regulate gene expression post‐transcriptionally by base pairing with the mRNA.
Yishai Shimoni   +6 more
doaj   +1 more source

Post-transcriptional gene regulation: From genome-wide studies to principles [PDF]

open access: yes, 2018
.: Post-transcriptional regulation of gene expression plays important roles in diverse cellular processes such as development, metabolism and cancer progression.
Galgano, A.   +3 more
core  

Optimisation of the Schizosaccharomyces pombe urg1 expression system [PDF]

open access: yes, 2013
The ability to study protein function in vivo often relies on systems that regulate the presence and absence of the protein of interest. Two limitations for previously described transcriptional control systems that are used to regulate protein expression
A Yamashita   +34 more
core   +2 more sources

Correction to: Post-Transcriptional Gene Regulation [PDF]

open access: yes, 2022
The book was inadvertently published with incorrect affiliation for the authors "Katherine B. Henke, Rachel M. Miller, Rachel A. Knoener, Mark Scalf, Michele Spiniello, and Lloyd M. Smith" in the contributors' list in FM and in the metadata of chapter 12.
openaire   +2 more sources

Learning the language of post-transcriptional gene regulation [PDF]

open access: yesGenome Biology, 2013
A large-scale RNA in vitro selection study systematically identified RNA recognition elements for 205 RNA-binding proteins belonging to families conserved in most eukaryotes.
Thomas Tuschl   +2 more
openaire   +3 more sources

Autophagy in cancer and protein conformational disorders

open access: yesFEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Home - About - Disclaimer - Privacy