Results 101 to 110 of about 625,558 (252)

Dysbiosis May Trigger Autoimmune Diseases via Inappropriate Post-Translational Modification of Host Proteins

Frontiers in Microbiology, 2016
The gut ecosystem with myriads of microorganisms and the high concentration of immune system cells can be considered as a separate organ on its own.
A. Lerner, R. Aminov, T. Matthias
semanticscholar   +1 more source

Post-Translational Modifications of TRP Channels [PDF]

Cells, 2014
Transient receptor potential (TRP) channels constitute an ancient family of cation channels that have been found in many eukaryotic organisms from yeast to human. TRP channels exert a multitude of physiological functions ranging from Ca2+ homeostasis in the kidney to pain reception and vision. These channels are activated by a wide range of stimuli and
Olaf Voolstra, Armin Huber
openaire   +3 more sources

Charting the protein complexome in yeast by mass spectrometry [PDF]

, 2002
It has become evident over the past few years that many complex cellular processes, including control of the cell cycle and ubiquitin-dependent proteolysis, are carried out by sophisticated multisubunit protein machines that are dynamic in abundance ...
Cope, Greg, Deshaies, Raymond J., Lyapina, Svetlana, McDonald, W. Hayes, Seol, Jae Hong, Shevchenko, Andrej, Shevchenko, Anna, Verma, Rati, Yates, John R., III   +8 more
core  

Differential effects of sumoylation on the activities of CCAAT enhancer binding protein alpha (C/EBPa) p42 versus p30 may contribute in part, to aberrant C/EBPa activity in acute leukemias

Hematology Reports, 2011
In this study, we have examined the role of post-translational modification of the myeloid master regulator C/EBP by small ubiquitin-related modifier (SUMO).
William Hankey, Matthew Silver, Hong Sun, Terry Zibello, Nancy Berliner, Arati Khanna-Gupta   +5 more
doaj   +1 more source

Characteristics of protein kinases in Lemna Paucicostana Hegelm [PDF]

, 1985
Post-translational modification of proteins or enzymes by phosphorylation represents an important mechanism in the control of cellular processes. Studies in animal cells have shown that the activities of a number of key ...Thesis--University of Tsukuba ...
Kato Ryoichi
core  

5mC-hydroxylase activity is influenced by the PARylation of TET1 enzyme [PDF]

, 2015
5-hydroxymethylcytosine is a new epigenetic modification deriving from the oxidation of 5-methylcytosine by the TET hydroxylase enzymes. DNA hydroxymethylation drives DNA demethylation events and is involved in the control of gene expression ...
CAIAFA, Paola, CICCARONE, FABIO, VALENTINI, ELISABETTA, ZAMPIERI, Michele   +3 more
core   +2 more sources

Cysteine S-linked N-acetylglucosamine (S-GlcNAcylation), A New Post-translational Modification in Mammals*

Molecular & Cellular Proteomics, 2016
Intracellular GlcNAcylation of Ser and Thr residues is a well-known and widely investigated post-translational modification. This post-translational modification has been shown to play a significant role in cell signaling and in many regulatory processes
Jason C. Maynard, A. Burlingame, K. Medzihradszky   +2 more
semanticscholar   +1 more source

KAP1 is a Novel Substrate for the Arginine Methyltransferase PRMT5 [PDF]

, 2015
KRAB-associated protein 1 (KAP1), the transcriptional corepressor of Kruppel-associated box zinc finger proteins (KRAB-ZFPs), is subjected to multiple post-translational modifications that are involved in fine-tuning of the multiple biological functions ...
Cesaro, Elena, Ciano, Michela, Costanzo, Paola, Di Caprio, Roberta, Montano, Giorgia   +4 more
core   +2 more sources

Lactylation: The emerging frontier in post-translational modification

Frontiers in Genetics
Lactate, a metabolic byproduct, has gained recognition as a highly influential signaling molecule. Lactylation, an emerging form of post-translational modification derived from lactate, plays a crucial role in numerous cellular processes such as ...
Zhou Lu, Xueting Zheng, Mingsong Shi, Yuan Yin, Yuanyuan Liang, Zhiyan Zou, Chenghe Ding, Yuanjing He, Yan Zhou, Xiaoan Li, Xiaoan Li   +10 more
doaj   +1 more source

Tyrosine dephosphorylation of H2AX modulates apoptosis and survival decisions. [PDF]

, 2009
Life and death fate decisions allow cells to avoid massive apoptotic death in response to genotoxic stress. Although the regulatory mechanisms and signalling pathways controlling DNA repair and apoptosis are well characterized, the precise molecular ...
Cook, Peter J, Glass, Christopher K, Ju, Bong Gun, Rosenfeld, Michael G, Telese, Francesca, Wang, Xiangting   +5 more
core   +2 more sources