Results 101 to 110 of about 445,929 (364)
Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation
FEBS Letters, EarlyView.The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt +8 more
wiley +1 more source
Potential coordination role between O-GlcNAcylation and epigenetics
Protein & Cell, 2017 Dynamic changes of the post-translational O-GlcNAc modification (O-GlcNAcylation) are controlled by O-linked β-N-acetylglucosamine (O-GlcNAc) transferase (OGT) and the glycoside hydrolase O-GlcNAcase (OGA) in cells. O-GlcNAcylation often occurs on serine
Donglu Wu, Yong Cai, Jingji Jin
doaj +1 more source
Semi-terminal modifications of demi-normal pairs [PDF]
arXiv, 2013 For a quasi-projective demi-normal pair (X, \Delta), we prove that there exists a semi-canonical modification and semi-terminal modification of (X, \Delta).
arxiv
Ensembles of Random SHAPs [PDF]
arXiv, 2021 Ensemble-based modifications of the well-known SHapley Additive exPlanations (SHAP) method for the local explanation of a black-box model are proposed. The modifications aim to simplify SHAP which is computationally expensive when there is a large number of features.
arxiv
Lipoproteins of Mycobacterium tuberculosis : an abundant and functionally diverse class of cell envelope components [PDF]
, 2004 Mycobacterium tuberculosis remains the predominant bacterial scourge of mankind. Understanding of its biology and pathogenicity has been greatly advanced by the determination of whole genome sequences for this organism.
Harrington, Dean, Sutcliffe, Iain
core +1 more source
Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells
Molecular Oncology, EarlyView.In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi +3 more
wiley +1 more source
Post-translational protein lactylation modification in health and diseases: a double-edged sword
Journal of Translational MedicineAs more is learned about lactate, it acts as both a product and a substrate and functions as a shuttle system between different cell populations to provide the energy for sustaining tumor growth and proliferation.
Hang Gong +4 more
doaj +1 more source
Frontiers in Microbiology, 2014 PII proteins are pivotal players in the control of nitrogen metabolism in bacteria and archaea, and are also found in the plastids of plants. PII proteins control the activities of a diverse range of enzymes, transcription factors and membrane transport ...
Mike eMerrick +2 more
doaj +1 more source
On the Staruszkiewicz Modification of the Schroedinger Equation [PDF]
arXiv, 1999 We discuss Staruszkiewicz's nonlinear modification of the Schr\"{o}dinger equation. It is pointed out that the expression for the energy functional for this modification is not unique as the field-theoretical definition of energy does not coincide with the quantum-mechanical one.
arxiv
MS²PIP prediction server : compute and visualize MS² peak intensity predictions for CID and HCD fragmentation [PDF]
, 2015 We present an MS2 peak intensity prediction server that computes MS2 charge 2+ and 3+ spectra from peptide sequences for the most common fragment ions. The server integrates the Unimod public domain post-translational modification database for modified ...
Degroeve, Sven +2 more
core +2 more sources