Results 261 to 270 of about 445,929 (364)

Engineering the Future of Restorative Clinical Peripheral Nerve Surgery

Advanced Healthcare Materials, EarlyView.
What if damaged nerves could regenerate more effectively? This review unveils cutting‐edge strategies to restore nerve function, from biomaterial scaffolds and bioactive molecules to living engineered tissues. By accelerating axonal regrowth, preserving Schwann cells, and enhancing connectivity, these approaches are reshaping nerve repair—offering new ...
Justin C. Burrell, Zarina S. Ali, Eric L. Zager, Joseph M. Rosen, Mykhailo M. Tatarchuk, D. Kacy Cullen   +5 more
wiley   +1 more source

Novel post-translational modification learning signature reveals B4GALT2 as an immune exclusion regulator in lung adenocarcinoma. [PDF]

J Immunother Cancer
Zhang P, Wang D, Zhou G, Jiang S, Zhang G, Zhang L, Zhang Z.   +6 more
europepmc   +1 more source

Gasotransmitters in Modern Medicine: Promises and Challenges in the Use of Porous Crystalline Carriers

Advanced Healthcare Materials, EarlyView.
This perspective provides an overview of the growing interest in utilizing various gasotransmitters—small gaseous signaling molecules namely nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S)—for several therapeutic applications, with emphasis on the potential use of porous materials as carriers to provide safe and controlled local ...
Rosana V. Pinto, Moisés L. Pinto, Christian Serre   +2 more
wiley   +1 more source

Synthetic mycolates derivatives to decipher protein mycoloylation, a unique post-translational modification in bacteria. [PDF]

J Biol Chem
Lesur E, Zhang Y, Dautin N, Dietrich C, Li de la Sierra-Gallay I, Augusto LA, Rollando P, Lazar N, Urban D, Doisneau G, Constantinesco-Becker F, Van Tilbeurgh H, Guianvarc'h D, Bourdreux Y, Bayan N.   +14 more
europepmc   +1 more source

Structural determinants of post-translational modification and catalytic specificity for the lipoyl domains of the pyruvate dehydrogenase multienzyme complex of Escherichia coli

, 2000
D. Dafydd Jones, H.James Horne, Pedro A. Reche, Richard N. Perham   +3 more
openalex   +2 more sources

Global Regulation of Post-translational Modifications on Core Histones [PDF]

, 2002
Scott Galasinski, Donna F. Louie, Kristen K. Gloor, Katheryn A. Resing, Natalie G. Ahn   +4 more
openalex   +1 more source

Reinforced Polymer–Nanoparticle Hydrogels for Subcutaneous and Sustained Delivery of Trastuzumab

Advanced Healthcare Materials, EarlyView.
Biologic therapy development is rapidly accelerating, requiring extended delivery formulation strategies. Supramolecular hydrogels and electrostatic complexation create subcutaneous depots that release clinically relevant trastuzumab doses in a controlled manner through simple component mixing without chemical modifications.
Giovanni Bovone, Stéphane Bernhard, Guillaume Jacquot, Vincent Mittelheisser, Céline Mirjolet, Elia A. Guzzi, Lorenza Garau Paganella, Luca Liebi, Julien Draussin, Pedro Lopez Navarro, Elsa Barbé, Olivier Lefebvre, Jacky G. Goetz, Loic J. Charbonnière, Xavier Pivot, Sébastien Harlepp, Mark W. Tibbitt, Alexandre Detappe   +17 more
wiley   +1 more source

Post translational modification regulation of transcription factors governing pancreatic β-cell identity and functional mass. [PDF]

Front Endocrinol (Lausanne)
Wong A, Alejandro EU.
europepmc   +1 more source

Alterations in the post-translational modification and intracellular trafficking of clusterin in MCF-7 cells during apoptosis [PDF]

, 2003
Jacintha O’Sullivan, Lorna Whyte, Jim Drake, Martin Tenniswood   +3 more
openalex   +1 more source

Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy

Advanced Healthcare Materials, EarlyView.
The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq, Punnya Anil Kumar Jeeja, Sudip Kumar Dam, Sabya Sachi Das, Juan L. Vivero‐Escoto   +4 more
wiley   +1 more source