Results 191 to 200 of about 222,502 (279)

Gasotransmitters in Modern Medicine: Promises and Challenges in the Use of Porous Crystalline Carriers

Advanced Healthcare Materials, EarlyView.
This perspective provides an overview of the growing interest in utilizing various gasotransmitters—small gaseous signaling molecules namely nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S)—for several therapeutic applications, with emphasis on the potential use of porous materials as carriers to provide safe and controlled local ...
Rosana V. Pinto, Moisés L. Pinto, Christian Serre   +2 more
wiley   +1 more source

The role of oxidative post-translational modifications in type 1 diabetes pathogenesis. [PDF]

Front Immunol
Alhamar G, Vinci C, Franzese V, Tramontana F, Le Goux N, Ludvigsson J, Nissim A, Strollo R.   +7 more
europepmc   +1 more source

Post-translational Modification of Bid Has Differential Effects on Its Susceptibility to Cleavage by Caspase 8 or Caspase 3 [PDF]

, 2003
Mauro Degli Esposti, Gilles Ferry, Peggy Masdehors, Jean A. Boutin, John A. Hickman, Caroline Dive   +5 more
openalex   +1 more source

Reinforced Polymer–Nanoparticle Hydrogels for Subcutaneous and Sustained Delivery of Trastuzumab

Advanced Healthcare Materials, EarlyView.
Biologic therapy development is rapidly accelerating, requiring extended delivery formulation strategies. Supramolecular hydrogels and electrostatic complexation create subcutaneous depots that release clinically relevant trastuzumab doses in a controlled manner through simple component mixing without chemical modifications.
Giovanni Bovone, Stéphane Bernhard, Guillaume Jacquot, Vincent Mittelheisser, Céline Mirjolet, Elia A. Guzzi, Lorenza Garau Paganella, Luca Liebi, Julien Draussin, Pedro Lopez Navarro, Elsa Barbé, Olivier Lefebvre, Jacky G. Goetz, Loic J. Charbonnière, Xavier Pivot, Sébastien Harlepp, Mark W. Tibbitt, Alexandre Detappe   +17 more
wiley   +1 more source

Control of Snail1 protein stability by post-translational modifications: the basis for a complex regulation of Snail1 function. [PDF]

Int J Biol Sci
García de Herreros A.
europepmc   +1 more source

Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy

Advanced Healthcare Materials, EarlyView.
The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq, Punnya Anil Kumar Jeeja, Sudip Kumar Dam, Sabya Sachi Das, Juan L. Vivero‐Escoto   +4 more
wiley   +1 more source

Post-translational modifications of the histone variant h2az

Stem Cell Research, 2014
Ana Sevilla, Olivier Binda
doaj   +1 more source

Post-translational modifications of immune checkpoints: unlocking new potentials in cancer immunotherapy. [PDF]

Exp Hematol Oncol
Hu Q, Shi Y, Wang H, Bing L, Xu Z.
europepmc   +1 more source

Does Post-translational Modification Influence Chaperone-like Activity of .ALPHA.-Crystallin? I. Study on Phosphorylation.

, 2001
Akira Kamei, Takayuki HAMAGUCHI, Nobuyuki Matsuura, Katsuyoshi Masuda   +3 more
openalex   +2 more sources

Translational and post-translational modifications of proteins as a new mechanism of action of Alpha-Interferon: Review article [PDF]

, 2004
Michele Caraglia, Giovanni Vitale, Maurizio Marra, Salvatore Del Prete, Alessandro Lentini, Alfredo Budillon, Simone Beninati, A. Abbruzzese   +7 more
openalex   +1 more source