Results 91 to 100 of about 15,651,159 (302)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

A ambivalência da ciência em Zygmunt Bauman

open access: yesCiências Sociais Unisinos, 2006
This paper intends to emphasize the presence of the phenomenon of ambivalence in the concept of science as presented by Bauman. Therefore, it discusses the role of science in modernization and its failure as a tool designed to overcome ambivalence. The
Paolo Totaro
doaj  

China labor unrest linked to global economic slowdown, Europe debt crisis - Washington Post [PDF]

open access: yes, 2011
This document is part of a digital collection provided by the Martin P. Catherwood Library, ILR School, Cornell University, pertaining to the effects of globalization on the workplace worldwide.
China Labor Watch, Washington Post
core   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Post-postmodernismo

open access: yesRevista Reflexiones, 1969
Este artículo es una crítica al concepto de post-postmodernismo. En él se analiza las características fundamentales del post-postmodernismo con respecto al postmodernismo, en cuanto este último es el origen del primero. Asimismo, se establece la relación entre neoliberalismo, globalización y post-postmodernismo, como un medio para acceder al contexto ...
openaire   +4 more sources

A tensão pós-moderna no cinema

open access: yesCiências Sociais Unisinos, 2007
Increasing interest in new special effect technologies has fostered new possibilities in the use of cinema apparatuses. Digital as well as other technologies, which have been used to represent illusion, fantasy or realism, have been a feature of ...
Maria Helena Braga e Vaz da Costa
doaj  

A Stochastic Dominance Approach to Spanning [PDF]

open access: yes
We develop a Stochastic Dominance methodology to analyze if new assets expand theinvestment possibilities for rational nonsatiable and risk-averse investors.
Post, G.T.
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Maffesoli e a "investigação do sentido" - das identidades às identificações

open access: yesCiências Sociais Unisinos, 2008
Michel Maffesoli¿s work tries to understand the common man without despising him as something insignificant if compared to the researcher of academic formation.
Eduardo Portanova Barros
doaj  

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