Results 101 to 110 of about 15,651,159 (302)

Writing to learn on the wards: scholarly blog posts by medical students and housestaff at a teaching hospital

Medical Education Online, 2019
Background: Informative writing is a valuable tool for learning and fostering the scientific process. Pearls4Peers (P4P) is an educational open-access website dedicated to scholarly blog posts in hospital medicine based on questions raised during ward ...
Farrin A. Manian, Felicia Hsu
doaj   +1 more source

Depression: post-melancholia, post-fluxus, post-communist, post-capitalist, post-digital, post-prozac

, 2016
"Depression" has two conventional meanings: It can refer to an individual state of mind or to such collective conditions as economic crises. Each yielded their own visual languages and performances in the arts. With today's entrepreneurship of the self, the two states seem to have converged.
openaire  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Pós-desenvolvimento, indicadores e culturas de auditoria: reflexões críticas sobre governança e desenvolvimento

Ciências Sociais Unisinos, 2013
The article explores three dimensions of the recent debate on development. Firstly, it briefly analyzes the critique of development in the proposal that became known as post- development. Secondly, the possible connection between post-development and the
Guilherme Francisco Waterloo Radomsky
doaj  

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Prótesis parcial fija: análisis biomecánico sobre distribución de esfuerzos entre tres alternativas de retención Fixed partial prosthesis: biomechanical analysis of stress distribution among three retention alternatives

Revista Facultad de Odontología Universidad de Antioquia, 2010
INTRODUCCIÓN: el propósito de este estudio fue analizar la distribución de los esfuerzos entre tres alternativas de retención de una prótesis dental parcial fija de tres unidades, utilizando el método de elementos finitos (MEF).
Edwin Chica, Federico Latorre, Sergio Agudelo   +2 more
doaj  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

International pregnancy loss/ miscarriage day posts shared on Instagram: a content analysisAJOG Global Reports at a Glance

AJOG Global Reports
Background: Miscarriage refers to the loss of a fetus before the completion of 28 weeks of gestation. The prevalence of miscarriage across all age groups ranges from 12% to 20%.
Atikah Sayogo Putri, Achmad Kemal Harzif, Putri Nurbaeti, Aisyah Retno Puspawardani, Nafi'atul Ummah, Shakira Amirah, Muhammad Candrika Agyawisnu Yuwono, Mila Maidarti, Kanadi Sumapraja   +8 more
doaj   +1 more source

Testing for Third-Order Stochastic Dominance with Diversification Possibilities [PDF]

We derive an empirical test for third-order stochastic dominance that allows fordiversification between choice alternatives. The test can be computed usingstraightforward linear programming.
Post, G.T.
core   +1 more source