Results 121 to 130 of about 8,368,252 (317)

Annual report, fiscal year 1985 : follow-up report on audit recommendations.

open access: yes, 1985
"A Report to the Kansas Legislature by the Legislative Post Audit Committee, state of Kansas."; "July 8, 1985."; Fiscal year ends June 30.Constitutes the annual report of the ...
Kansas. Legislative Post Audit Committee.
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Considerations of post application in restoration of endodontically treated teeth: A review

open access: yesمجله دانشکده دندانپزشکی اصفهان, 2010
Using a post is a common method in providing the adequate retention for coronal restoration of endodontically treated teeth. With proper post selection, the success rate of this kind of treatment is considerable.
M Ebrahimi Dastgerdi,   +6 more
doaj  

Depression: post-melancholia, post-fluxus, post-communist, post-capitalist, post-digital, post-prozac

open access: yes, 2016
"Depression" has two conventional meanings: It can refer to an individual state of mind or to such collective conditions as economic crises. Each yielded their own visual languages and performances in the arts. With today's entrepreneurship of the self, the two states seem to have converged.
openaire  

Annual report, fiscal year 1987 : follow-up report on audit recommendations.

open access: yes, 1987
"A Report to the Kansas Legislature by the Legislative Post Audit Committee, state of Kansas."; Fiscal year ends June 30.Constitutes the annual report of the ...
Kansas. Legislative Post Audit Committee.
core  

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Washington Post Obituary for Fred W. Dickens (July 9, 1974)

open access: yes, 1974
An obituary for Fred W. Dickens that appeared in the July 9, 1974 Washington Post. The obituary had a photograph and gave basic information on his life.
Washington Post;
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Przeto, ktokolwiek by jadł chleb i pił z kielicha Pańskiego niegodnie (…) sąd własny je i pije (1 Kor 11,27-29) – czyli o właściwym przygotowaniu się do Świętej Eucharystii według nauki Ojców Kościoła

open access: yesElpis, 2014
„Sakrament Sakramentów” bądź „Misterium Misteriów”, jak nazywana jest Święta Eucharystia to rekapitulacja tajemnicy ekonomii zbawienia człowieka. Jej znaczenie, rola i waga, jako centralnego miejsca żywego organizmu Kościoła, jest niepodważalna. Wszystko
Adam Magruk
doaj  

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