Results 111 to 120 of about 10,116,795 (305)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

A crítica pós-moderna: analítica da interação e da sociabilidade

Ciências Sociais Unisinos, 2007
As one attempts to approach the multiple dimensions of modernity and its nexus with contemporary theoretical debates, one should not omit the different contributions made by the so-called post-modern critique. This article discusses these contributions
Carlos A. Gadea
doaj  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Annual report, fiscal year 1985 : follow-up report on audit recommendations.

, 1985
"A Report to the Kansas Legislature by the Legislative Post Audit Committee, state of Kansas."; "July 8, 1985."; Fiscal year ends June 30.Constitutes the annual report of the ...
Kansas. Legislative Post Audit Committee.
core   +1 more source

O discurso do movimento #OcupeOCocó e sua luta pela significação nas redes sociais

Ciências Sociais Unisinos, 2017
The purpose of this article is to analyze the speech #OcupeOCocó, a popular movement in defense of Coco Park, in Fortaleza (Brazil), which emerged on social networks in July 2013, and its struggle for meaning in social networks from posts and users ...
Luciana Correia Barbosa, Sérgio Carvalho Benício de Mello, Henrique Muzzio   +2 more
doaj  

To post or not to post: How minority opinion and posting frequency impact online review posting

International Journal of Research in Marketing
Consumers are often exposed to prior reviews when considering posting themselves. We examine how finding one’s opinion in the minority (vs. majority) of previous ratings affects a consumer’s decision to post. Specifically, we contrast the posting decisions of frequent posters with those of less frequent posters.
Möller-Herm, Jana, Gottschalk, Sabrina, Mafael, Alexander   +2 more
openaire   +1 more source

Annual report, fiscal year 1984 : follow-up on audit recommendations.

, 1984
"A Report to the Kansas Legislature by the Legislative Post Audit Committee, state of Kansas."; "August 27, 1984."; Fiscal year ends June 30.Constitutes the annual report of the ...
Kansas. Legislative Post Audit Committee.
core   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Other title: Financial and Compliance Audit Reports provided by the Legislative Division of Post Audit, State of Kansas, 2016-2017

, 2016
application/pdf; "A Report to the Legislative Post Audit Committee"--Cover.A set of 4 Financial and Compliance Audit Reports provided by the the Legislative Division of Post Audit, State of Kansas.Financial and Compliance Audit Report : Kansas Lottery ...
Kansas. Legislature. Legislative Division of Post Audit.
core   +1 more source