Results 41 to 50 of about 1,252,023 (295)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Recurrent DNNs and its Ensembles on the TIMIT Phone Recognition Task

open access: yes, 2018
In this paper, we have investigated recurrent deep neural networks (DNNs) in combination with regularization techniques as dropout, zoneout, and regularization post-layer.
Michalek, Josef   +2 more
core   +1 more source

Depth from Monocular Images using a Semi-Parallel Deep Neural Network (SPDNN) Hybrid Architecture [PDF]

open access: yes, 2018
Deep neural networks are applied to a wide range of problems in recent years. In this work, Convolutional Neural Network (CNN) is applied to the problem of determining the depth from a single camera image (monocular depth).
Bazrafkan, S.   +3 more
core   +2 more sources

Trueness and depth discrepancy of post-space scans using an intraoral scanner: influence of preparation dimensions: an in vitro study

open access: yesBMC Oral Health
Background Intraoral scanning of post spaces offers a potential alternative to conventional impressions, but its effectiveness depends on overcoming limitations influenced by post space dimensions.
Mostafa Shahin Zaki   +2 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Training mathematical skills in school children: Some preliminary results. [PDF]

open access: yes, 2019
The present study is a further development of an earlier research on school failure. The aim is to develop sound, simple, effective evaluation and training procedures for children with difficulties to learn mathematics.
Galindo, Edgar
core  

TuNet: End-to-end Hierarchical Brain Tumor Segmentation using Cascaded Networks

open access: yes, 2019
Glioma is one of the most common types of brain tumors; it arises in the glial cells in the human brain and in the spinal cord. In addition to having a high mortality rate, glioma treatment is also very expensive.
A Gholami   +8 more
core   +1 more source

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

open access: yesFEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia   +6 more
wiley   +1 more source

Spectropolarimetry of the Type IIb Supernova 2001ig [PDF]

open access: yes, 2007
We present spectropolarimetric observations of the Type IIb SN 2001ig in NGC 7424; conducted with the ESO VLT FORS1 on 2001 Dec 16, 2002 Jan 3 and 2002 Aug 16 or 13, 31 and 256 days post-explosion.
Appenzeller I.   +18 more
core   +3 more sources

Home - About - Disclaimer - Privacy