Results 61 to 70 of about 1,252,023 (295)

Seal capability of interim post and core crown with temporary cements

Brazilian Oral Research, 2010
The purpose of the present study was to evaluate the in vitro seal capability of interim post and core crown restorations. Eighty teeth were selected and divided into 8 groups. Four experimental groups received interim posts and core crowns. Half of each
Guilherme Bönecker-Valverde, Claudio Maniglia-Ferreira, Gisele Priscila Abi-Rached, Brenda Paula Figueiredo de Almeida Gomes, Marcelo Ferraz Mesquita   +4 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Linguistic Reflection in Java [PDF]

, 1998
Reflective systems allow their own structures to be altered from within. Here we are concerned with a style of reflection, called linguistic reflection, which is the ability of a running program to generate new program fragments and to integrate these ...
Kirby, G. N. C., Morrison, R., Stemple, D. W.   +2 more
core   +4 more sources

Retention of Cast Posts Cemented with Two Commonly Used Conventional and Two Resin Cements and the Mode of Root Fracture Following Their Removal

Frontiers in Dentistry, 2021
Objectives: This study aimed to compare the retention of cast posts cemented with four types of cements and assess the mode of root fracture following their removal.
Azadeh Hesarkhani, Farnoush Fotovat, Fatemeh Saneian, Hosein Akbari, Hanif Allahbakhshi   +4 more
doaj  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Astrophysical foregrounds and primordial tensor-to-scalar ratio constraints from CMB B-mode polarization observations

, 2012
We study the effects of astrophysical foregrounds on the ability of CMB B-mode polarization experiments to constrain the primordial tensor-to-scalar ratio, r.
Errard, Josquin, Stompor, Radek
core   +3 more sources

Ascertaining the nature and timing of mire degradation : using palaeoecology to assist future conservation management in Northern England [PDF]

, 2017
This study was initiated under contract VT0419 from English Nature (Natural England) to CECQR. In 2015, additional funding was provided by the Yorkshire Peat Partnership, for 210Pb dating, to refine age–depth estimates.
Alistair Crowle, Dmitri Mauquoy, Frank Chambers, John Daniell, Julia McCarroll, Julia Webb, Nicole Sanderson, null null, Phil Toms, Tim Thom   +9 more
core   +3 more sources

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Outcome measures in post-stroke arm rehabilitation trials: do existing measures capture outcomes that are important to stroke survivors, carers, and clinicians? [PDF]

, 2019
Objective: We sought to (1) identify the outcome measures currently used across stroke arm rehabilitation randomized trials, (2) identify and compare outcomes important to stroke survivors, carers and clinicians and (3) describe where existing research ...
Alex Pollock, Dunham RB., Franceschini M, Frederike van Wijck, Intercollegiate Stroke Working Party, Julie Duncan Millar, Myzoon Ali, Pollock A, Purton J., Seale C, Van Breda A   +10 more
core   +2 more sources

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source