Results 71 to 80 of about 263,806 (296)

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Adhesive cementation of zirconia posts to root dentin: evaluation of the mechanical cycling effect

Brazilian Oral Research, 2008
This study evaluated the effect of mechanical cycling on the bond strength of zirconia posts to root dentin. Thirty single-rooted human teeth were transversally sectioned to a length of 16 mm. The canal preparation was performed with zirconia post system
Graziela Ávila Galhano, Renata Marques de Melo, Carlos Augusto Pavanelli, Paolo Baldissara, Roberto Scotti, Luiz Felipe Valandro, Marco Antonio Bottino   +6 more
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

The Effect of Viscosity and Application Mode of Phosphoric Acid on Bond Strength of GlassFiber Post

Clinical, Cosmetic and Investigational Dentistry, 2020
Maria Fernanda Costa Scholz,1 Rossana Aboud Matos de Almeida,2 Nelson Scholz,1 Giovana M Gomes,1 María José Masson-P,1 Alessandro D Loguercio,1,3 Alessandra Reis,1 Matheus C Bandéca2 1Department of Restorative Dentistry, State ...
Costa Scholz MF, Aboud Matos de Almeida R, Scholz N, Gomes GM, Masson-P MJ, Loguercio AD, Reis A, Bandéca MC   +7 more
doaj  

Effect of curing mode on the hardness of dual-cured composite resin core build-up materials

Brazilian Oral Research, 2010
This study evaluated the Knoop Hardness (KHN) values of two dual-cured composite resin core build-up materials and one resin cement exposed to different curing conditions. Two dual-cured core build-up composite resins (LuxaCore®-Dual, DMG; and FluoroCore®
César Augusto Galvão Arrais, Aline de Cerqueira Kasaz, Luís Gustavo Barrote Albino, José Augusto Rodrigues, Andre Figueiredo Reis   +4 more
doaj   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Retention of Cast Posts Cemented with Two Commonly Used Conventional and Two Resin Cements and the Mode of Root Fracture Following Their Removal

Frontiers in Dentistry, 2021
Objectives: This study aimed to compare the retention of cast posts cemented with four types of cements and assess the mode of root fracture following their removal.
Azadeh Hesarkhani, Farnoush Fotovat, Fatemeh Saneian, Hosein Akbari, Hanif Allahbakhshi   +4 more
doaj  

Seal capability of interim post and core crown with temporary cements

Brazilian Oral Research, 2010
The purpose of the present study was to evaluate the in vitro seal capability of interim post and core crown restorations. Eighty teeth were selected and divided into 8 groups. Four experimental groups received interim posts and core crowns. Half of each
Guilherme Bönecker-Valverde, Claudio Maniglia-Ferreira, Gisele Priscila Abi-Rached, Brenda Paula Figueiredo de Almeida Gomes, Marcelo Ferraz Mesquita   +4 more
doaj   +1 more source

An Alternative Technique for Cementation of Cast Post and Core Restoration

Journal of Dental and Allied Sciences, 2015
Cementation of cast post and core restoration involves the application of luting cement in the prepared post space which is intra radicular. Commonly an endodontic instrument, lentulo spiral, and rotary hand piece at slow speed is used. Occasionally, the luting cement does not reach the base or is not uniformly spread on to the walls of the prepared ...
BhushanSatish Gaikwad, MayuraS Badgujar
openaire   +1 more source

FINITE ELEMENT ANALYSIS OF MAXILLARY CENTRAL INCISORS RESTORED WITH VARIOUS POST-AND-CORE APPLICATIONS [PDF]

, 2009
The purpose of this study was to investigate the effect of rigidity of post core systems on stress distribution by the theoretical technique, finite element stress-analysis method.

core