Results 81 to 90 of about 263,806 (296)

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Analysis of bacterial biofilm formed on intraradicular posts attached to an intraoral device

RGO: Revista Gaúcha de Odontologia
Objetive This study aimed to evaluate, in situ, the microbiological composition of the biofilm formed on intraradicular posts attached to removable intraoral devices.
Flávia Lobato Rodrigues, Nicole Pinto Plein, Luiz Henrique Burnett Júnior, Francisco Montagner, Simone Bonato Luisi, Tiago André Fontoura de Melo   +5 more
doaj   +1 more source

Radiographic analysis of 1000 cast posts in Sergipe state, Brazil

Revista de Odontologia da UNESP, 2017
Introduction Endodontically treated teeth with extensive coronary destruction require posts and cores to enable prosthetic restoration. Despite the increasing use of prefabricated posts, cast metal posts and cores are still widely used.
Caroline Garcez MENDONÇA, José Rogério Vieira de ALMEIDA, Wilton Mitsunari TAKESHITA, Fábio MARTINS, Monica Silveira PAIXÃO   +4 more
doaj   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Post-processing of hollow-core photonic crystal fibers: selective hole inflation and tapering

, 2023
International audienceWe report on post-processing experiments using hollow-core photonic crystal fibers. We show that, by simultaneously heating and internally pressurizing the fibers, we can taper or modify the sizes of the fiber microstructure ...
Cordeiro, Cristiano, M B, Gerosa, Rodrigo, M, Gérôme, Frédéric, Amrani, Foued, Osório, Jonas, H, Machado, Guilherme, Benabid, Fetah   +6 more
core   +1 more source

Evaluation of the pattern dimensions of cast-metal posts in uniradicular teeth

Revista de Odontologia da UNESP
Introduction Accurate dimensions of cast-metal posts are relevant to the survival of dental prostheses. Objective The aim of this study was to verify if the dimensions of cast-metal posts accord with ideal clinical criteria.
Rafael de Assunção Vital, Jessica Silva Ribeiro, Sicknan Soares da Rocha   +2 more
doaj   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

Molecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan, Beatriz Martín‐Gracia, Eva Bassols‐Citores, Krizia Sagini, Maria K. Andersen, Tuula A. Nyman, May‐Britt Tessem, Morten B. Rye, Alicia Llorente   +8 more
wiley   +1 more source

In vitro fracture strength and modes of cast post and cores luted with self-adhesive resin-based cement

Brazilian Journal of Oral Sciences, 2019
Aim: Cast post and core (CPC) is the main used post type; however, the biomechanical behavior of CPCs adhesively luted to the dentin is still unclear. Therefore, we aimed to evaluate the fracture resistance (FR) and fracture modes of teeth restored with ...
Marcos C Pomini, Marina M Machado, Giovanny de Paula Quadros, Lidia O B Pinheiro, Adriana P B Samra   +4 more
doaj   +1 more source

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

Molecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau, Daniel Pincher, Clifford Young, Nicholas Chappell, Noor A. Lokman, Parul Mittal, Leigh Donnellan, Martin K. Oehler, Doug A. Brooks, Peter Hoffmann   +9 more
wiley   +1 more source

Influence of diameter and intraradicular post in the stress distribution. Finite element analysis

Revista de Odontologia da UNESP
Introduction The biomechanical behavior of endodontically treated teeth depending on the selected restorative material and tooth situation to be restored.
Cleidiel Aparecido Araujo LEMOS, Daniel Augusto de Faria ALMEIDA, Victor Eduardo de Souza BATISTA, Carol Cantieri MELLO, Fellippo Ramos VERRI, Eduardo Piza PELLIZZER, José Vitor Quinelli MAZARO   +6 more
doaj   +1 more source