Results 101 to 110 of about 74,395 (265)

Very High‐Frequency Oscillations in Mesial Temporal Lobe Epilepsy: Identifying the Epileptogenic Zone

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate the reliability of very high‐frequency oscillations (VHFOs, 500–2000 Hz) as biomarkers in identifying the epileptogenic zone (EZ) in mesial temporal lobe epilepsy (MTLE) patients. Methods We reviewed 19 MTLE patients who underwent stereo‐electroencephalography‐guided radiofrequency thermocoagulation.
Stéphane Jean, Yihai Dai, Yan Cui, Donghuo Deng, Zhe Qian, Panashe Tevin Tagu, Weitao Chen, Weihong Liu, Xiaoqiang Wei, Xinrong Fang, Shiwei Song   +10 more
wiley   +1 more source

Estimate of the Number of Patients Eligible for Treatment with Drotrecogin Alfa (Activated) Based on Differing International Indications: Post-hoc Analysis of an Inception Cohort Study in Australia and New Zealand [PDF]

, 2006
Simon Finfer, Tim Felton, Adrian Blundell, Jeffrey Lipman, Andrew Davies, Christine MacArthur, Lynette Newby, Rinaldo Bellomo, D. J. Wise, Graham Reece, Felicity Hawker, Lorisa Soloveychik, James A. Nicholls, Seton Henderson, Tamara D Hunt, Andrew D. Bersten, David Green, Brent Richards, Stuart A. Green, T S Solano, Arthas Flabouris, Chris Joyce, Anthony Limpus, Jeffrey Lipman, Andrew Turner, Simon Finfer, Vlad Szachin, M. Magnaye, Geoff Dobb, E. MacKenzie, Gordon morris, Imogen Mitchell, Vernon van Heerden, Brigitte Roberts, Michael J. O’Leary, John Myburgh, Craig French   +36 more
openalex   +1 more source

Post Hoc Bias in Treatment Decisions

JAMA Network Open
ImportanceA goal of health care is to reduce symptoms and improve health status, whereas continuing dubious treatments can contribute to complacency, discourage the search for alternatives, and lead to shortfalls in care.ObjectiveTo test a potential bias in intuitive reasoning following a marginal improvement in symptoms after a dubious treatment (post
Redelmeier, Donald A., Shafir, Eldar
openaire   +2 more sources

ADAPT NXT: Fixed Cycles or Every‐Other‐Week IV Efgartigimod in Generalized Myasthenia Gravis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This phase 3b, open‐label, randomized ADAPT NXT study investigated the efficacy, safety, and tolerability of efgartigimod administered in either a fixed cycles dosing regimen (3 cycles of 4 once‐weekly infusions, with 4 weeks between cycles) or a cycle followed by every‐other‐week (Q2W) dosing.
Ali A. Habib, Kristl G. Claeys, Vera Bril, Yessar Hussain, Kelly Gwathmey, Gregory Sahagian, Elena Cortés‐Vicente, Edward Brauer, Deborah Gelinas, Anne Sumbul, Rosa H. Jimenez, Daniela Hristova, Delphine Masschaele, Renato Mantegazza, Andreas Meisel, Shahram Attarian, On behalf of the ADAPT NXT Study Group   +16 more
wiley   +1 more source

Cognitive load decreases the sense of agency during continuous action

Acta Psychologica, 2023
The sense of agency that normally accompanies voluntary actions depends on a combination of sensory predictions and other inferences. For example, when people manipulate moving objects and rate their degree of control, control ratings are influenced by ...
John A. Dewey
doaj  

In defence of post-hoc explanations in medical AI [PDF]

arXiv
Since the early days of the Explainable AI movement, post-hoc explanations have been praised for their potential to improve user understanding, promote trust, and reduce patient safety risks in black box medical AI systems. Recently, however, critics have argued that the benefits of post-hoc explanations are greatly exaggerated since they merely ...
arxiv  

Patients' Global Impression of Change (PGIC) Score Compared to Monthly Migraine Days to Evaluate Treatment Persistence With Anti‐CGRP Monoclonal Antibodies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This study assessed whether continued treatment with anti‐CGRP monoclonal antibodies (mAbs) is driven more by reductions in monthly migraine days (MMDs) or patients' global impression of change (PGIC), a patient‐reported outcome. Among 169 patients treated with anti‐CGRP mAbs, 21.3% discontinued due to ineffectiveness. PGIC responders (≥ 5) at
Marina Romozzi, Catello Vollono, Paolo Calabresi, Francesco De Cesaris, Luigi Francesco Iannone   +4 more
wiley   +1 more source

CNS Mitochondria‐Derived Vesicle in Blood: Potential Biomarkers for Brain Mitochondria Dysfunction

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial dysfunction is a hallmark of neurodegenerative diseases like Alzheimer's (AD) and Parkinson's (PD). Our goal was to develop practical, noninvasive methods to assess mitochondrial status through the detection of mitochondria‐derived vesicles (MDVs).
Qi Liu, Wentao Chen, Yahong Wu, Zhen Guo, Jun Chen, Chen Tian, Pan Wang, Shaopeng Zeng, Bin Xu, Jing Duan, Shilong Han, Xiao Xiong, Jing Zhang   +12 more
wiley   +1 more source

Enhancing Reliability Through Interpretability: A Comprehensive Survey of Interpretable Intelligent Fault Diagnosis in Rotating Machinery

IEEE Access
This paper presents a comprehensive survey on interpretable intelligent fault diagnosis for rotating machinery, addressing the challenge of the “black box” nature of machine learning techniques that hampers reliability in automated ...
Gang Chen, Junlin Yuan, Yiyue Zhang, Hanyue Zhu, Ruyi Huang, Fengtao Wang, Weihua Li   +6 more
doaj   +1 more source

Time for some a priori thinking about post hoc testing [PDF]

, 2008
Graeme D. Ruxton, Guy Beauchamp
openalex   +1 more source