Paving the Way to Elucidate Hg's Role in Tumorigenesis
Advanced Science, EarlyView.Tumorigenesis can result from diverse environmental carcinogens. Among them, mercury—a lifelong bioaccumulative Group 2B carcinogen—has tumorigenic potential that remains poorly understood due to confounding co‐exposures and limited organ‐specific data.
Shouying Li +10 more
wiley +1 more source
Variation of the intraocular pressure in relation to time of death: Contribution to the determination of the true postmortem interval (PMI) [PDF]
, 2019 Introducción: La determinación del momento del fallecimiento, es un dato de singular importancia en Medicina Legal constituyendo por su complejidad en uno de los problemas que necesita evaluación objetiva en la Patología Forense.
Genero, Sebastian +3 more
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Distribution of artifactual gas on post-mortem multidetector computed tomography (MDCT) [PDF]
, 2011 L'imagerie est de plus en plus utilisée en médecine forensique. Actuellement, les connaissances nécessaires pour interpréter les images post mortem sont faibles et surtout celles concernant les artéfacts post mortem. Le moyen radiologique le plus utilisé
Egger, C.
core +1 more source
In vivo imaging enables high resolution preclinical trials on patients' leukemia cells growing in mice. [PDF]
, 2012 Xenograft mouse models represent helpful tools for preclinical studies on human tumors. For modeling the complexity of the human disease, primary tumor cells are by far superior to established cell lines.
Brentjens, Renier J. +12 more
core +7 more sources
Advanced Science, EarlyView.Phospholipase A2 (PLA2), a dormant enzyme, becomes lethal when activated—collapsing lungs in minutes. Our dual therapy (DOPS + varespladib) boosts survival from 0% to >90% in sepsis/ALI. A breakthrough for acute lung injury treatment. ABSTRACT This study reveals that phospholipase A2 (PLA2), normally stable and nontoxic, can be activated specifically ...
Jianyu Wang +7 more
wiley +1 more source
Forensic Science International: Reports, 2023 This study analyzed the differences in the decomposition patterns and post mortem intervals of hanged and surface carcasses using domestic pigs as human analogs. Six domestic pigs weighing between 25 kg and 30 kg were separated into two groups comprising
Cletus Obun Obun +6 more
doaj +1 more source
Post mortem interval estimation: features of сerebrospinaI fluid films autofluoresсent laser polarimetry [PDF]
, 2016 Тhe purpose of the work is development and testing of the two-dimensional Stokes-polarimetriс mapping оf biologiсal layers own fluoresсenсe to evaluаte ассuraсy of the post moгtem interval estimation using stаtistical analysis of post moгtem changes ...
Baсhynskyi, V.T. +4 more
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Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain
Advanced Science, EarlyView.This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao +7 more
wiley +1 more source
Various methods for the estimation of the post mortem interval from Calliphoridae: A review
Egyptian Journal of Forensic Sciences, 2015 Insects play a fundamental ecological role in the decomposition of organic matter. It is the natural tendency of sarcosaprophagous flies to find and colonize on a food source such as a cadaver as a natural means of survival.
Ruchi Sharma +2 more
doaj +1 more source
In Vitro Fertility of Post-thawed Epididymal Ram Spermatozoa After Storage at 5 °C Before Cryopreservation [PDF]
, 2013 This study addressed the effects of storage duration of epididymides at 5 °C before sperm collection and their fertility after cryopreservation in vitro.
fahrudin, M. (M) +2 more
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