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Update on Non-Pharmacological Interventions for Treatment of Post-Traumatic Headache [PDF]

Brain Sciences, 2022
Post-traumatic headache (PTH) is the most common sequelae of traumatic brain injury (TBI). Its phenotypic variability, absence of formal evidence-based guidelines for treatment and underdiagnosis have made its management a challenge for clinicians.
Matthew J. Lee, Yi Zhou, Brian D. Greenwald   +2 more
doaj   +4 more sources

White matter hyperintensities and cerebral microbleeds in persistent post-traumatic headache attributed to mild traumatic brain injury: a magnetic resonance imaging study [PDF]

The Journal of Headache and Pain, 2023
Objective To examine whether white matter hyperintensities (WMHs) and cerebral microbleeds (CMBs) are more prevalent in people with persistent post-traumatic headache attributed to mild traumatic brain injury (TBI), compared with healthy controls ...
Håkan Ashina, Rune H. Christensen, Haidar Muhsen Al-Khazali, Afrim Iljazi, Daniel Tolnai, Anna K. Eigenbrodt, Henrik B. W. Larsson, Henrik W. Schytz, Ulrich Lindberg, Faisal Mohammad Amin   +9 more
doaj   +2 more sources

CGRP-induced migraine-like headache in persistent post-traumatic headache attributed to mild traumatic brain injury [PDF]

The Journal of Headache and Pain, 2022
Objective To ascertain whether intravenous infusion of calcitonin gene-related peptide (CGRP) can induce migraine-like headache in people with persistent post-traumatic headache attributed to mild traumatic brain injury (TBI) and no pre-existing migraine.
Håkan Ashina, Afrim Iljazi, Haidar M. Al-Khazali, Thien Phu Do, Anna K. Eigenbrodt, Eigil L. Larsen, Amalie M. Andersen, Kevin J. Hansen, Karoline B. Bräuner, Basit Ali Chaudhry, Casper E. Christensen, Faisal Mohammad Amin, Henrik W. Schytz   +12 more
doaj   +2 more sources

Total tenderness score and pressure pain thresholds in persistent post-traumatic headache attributed to mild traumatic brain injury [PDF]

The Journal of Headache and Pain, 2022
Objective To investigate whether persistent post-traumatic headache attributed to mild traumatic brain injury (TBI) is associated with more pronounced pericranial tenderness and lower pressure pain thresholds (PPTs) in the head and neck region, compared ...
Håkan Ashina, Haidar Muhsen Al-Khazali, Afrim Iljazi, Sait Ashina, Faisal Mohammad Amin, Henrik Winther Schytz   +5 more
doaj   +2 more sources

Post-Traumatic Headache

Pediatric Neurology Briefs, 1988
The occurrence and persistence of headache after closed head injury was investigated in 129 children, 70 boys and 59 girls, during a follow-up period, average 5.9 yrs., in the Depts of Neuropsychology and Child Neurology, State University Hospital, P.O ...
J Gordon Millichap
doaj   +4 more sources

Introduction of a classification interview for post-traumatic headache after concussion [PDF]

The Journal of Headache and Pain
Background Mild traumatic brain injury (TBI) can cause temporary disruption to brain function, with up to half of those affected complaining of functional limitations up to 12 months after the initial injury.
Hannah S. Lyons, Matilde Sassani, Helen Brunger, Abigail Lake, Benjamin Jefferies, Mark Thaller, Andreas Yiangou, Victoria Homer, Shreshth Dharm-Datta, Henrietta Ellis, Manjit Matharu, Lisa J. Hill, James L. Mitchell, Alexandra J. Sinclair   +13 more
doaj   +2 more sources

Inflammation, brain connectivity, and neuromodulation in post-traumatic headache [PDF]

Brain, Behavior, & Immunity - Health
Post-traumatic headache (PTH) is a debilitating condition that affects individuals with different levels of traumatic brain injury (TBI) severity.
Fernando da Silva Fiorin, Caroline Cunha do Espírito Santo, Joyce T. Da Silva, Man-Kyo Chung   +3 more
doaj   +2 more sources

Effects of PDE-3 inhibition in persistent post-traumatic headache: evidence of cAMP-dependent signaling [PDF]

The Journal of Headache and Pain
Background Phosphodiesterase 3 (PDE-3) inhibition have been implicated in the neurobiologic underpinnings of migraine. Considering the clinical similarities between migraine and persistent post-traumatic headache (PPTH), we aimed to ascertain whether PDE-
Haidar M. Al-Khazali, Rune H. Christensen, Basit Ali Chaudhry, Anna G. Melchior, Messoud Ashina, Rami Burstein, Håkan Ashina   +6 more
doaj   +2 more sources

Hypersensitivity to BKCa channel opening in persistent post-traumatic headache [PDF]

The Journal of Headache and Pain
Background Large conductance  calcium-activated potassium (BKCa) channels have been implicated in the neurobiological underpinnings of migraine. Considering the clinical similarities between migraine and persistent post-traumatic headache (PPTH), we ...
Haidar M. Al-Khazali, Rune H. Christensen, David W. Dodick, Basit Ali Chaudhry, Anna G. Melchior, Rami Burstein, Håkan Ashina   +6 more
doaj   +2 more sources

An update on the management of post-traumatic headache [PDF]

Therapeutic Advances in Neurological Disorders, 2015
Recent studies from the UK give the debate about how to deal best with patients suffering from whiplash injury new impetus. Following whiplash injury, about 90% of patients complain about head and/or neck pain, as well as dizziness, sleep problems and ...
Mark Obermann, Steffen Naegel, Bert Bosche, Dagny Holle   +3 more
doaj   +4 more sources