Results 81 to 90 of about 5,677,469 (278)

CYP2D6‐Guided Opioid Therapy for Chronic Pain: A Multi‐Center Pragmatic Randomized Controlled Trial

Clinical Pharmacology &Therapeutics, EarlyView.
The analgesic effectiveness of several opioids depends on CYP2D6‐mediated metabolism to more active opioid receptor agonists. CYP2D6 activity is impacted by genetic variability and medications that inhibit CYP2D6. We conducted a pragmatic, multi‐center, randomized, controlled trial to determine whether CYP2D6‐guided opioid prescribing improves chronic ...
Todd C. Skaar, Rachel A. Myers, Roger B. Fillingim, John T. Callaghan, Kerri L. Cavanaugh, Hrishikesh Chakraborty, Jordan F. Baye, Emily J. Cicali, Michael T. Eadon, Erica N. Elwood, Elizabeth C. Harris, Lindsay J. Hines, Khoa A. Nguyen, Michelle A. Ramos, Marc Rosenman, Azita Sadeghpour, Saskia Shuman, Rajbir Singh, Emma M. Tillman, Christina M. Wyatt, Carol R. Horowitz, Deepak Voora, Lori A. Orlando, Josh F. Peterson, Larisa H. Cavallari, Julie A. Johnson, Paul R. Dexter, on behalf of the IGNITE Pragmatic Trials Network, L Orlando, D Voora, C Horowitz, C Horowitz, N Calman, T Skaar, T Skaar, P Dexter, T Skaar, P Dexter, J Johnson, L Cavallari, J Johnson, L Cavallari, J Johnson, L Cavallari, K Blake, K Blake, K Blake, J Peterson, J Peterson, K Cavanaugh, R Singh, R Singh, L Hines, C Wyatt, H Chakraborty, Christina Wyatt, Geoff Ginsburg, Kady‐Ann Steen‐Burrell, Bhargav Adagarla, Sarah George, Beth Harris, Jaclyn Holland, Yashika Johnson, Phyllis Kennel, Kristen Linney, Rania Metry, Rachel Myers, Wanda Parker, Gayle Passmore, Carol Pereira, Teji Rakhra‐Burris, Ryanne Wu, Ruth Lehan, Tyffany Locklear, Carol Horowitz, Michelle Ramos, Sabrina Clermont, Bart Ferket, Kenneth Fifer, Diane Hauser, Joseph Kannry, James Murrough, Aniwaa Owusu Obeng, Janet Seo, Tatiana Sabin, Nandini Shroff, Paul Dexter, Abi Colwell, Amy M. Breman, Zeruesenay Desta, Cathy Fulton, Jennelle C. Hodge, Sheryl Lynch, Jonathan Oliver, Victoria M. Pratt, Ross Robinson, Elizabeth Rowe, Jennifer Stuart, Emma Tillman, Ashley Vetor, Julie Johnson, Larisa Cavallari, Alexander Parker, Erica Elwood, Kathryn Blake, Emily Cicali, Kelsey Cook, Karam Diaby, Julio Duarte, Ben Duong, Karla Giron, Elizabeth Eddy, Julia Krutov, Carol Mathews, Haesuk Park, Robyn Nelson, Ryan Rhoden, Caroline Schlierle, Taylor Sullivan, Almut Winterstein, Kristen Wiisanen, Josh Peterson, Kerri Cavanaugh, Sara Van Driest, Sara Block, Jordan Baye, Michelle Benck, Chantel Bender, Sylvia Eluhu, Colette Free, Shane Gonnelly, Sarah Hedeen, Lindsay Hines, Steve Houtschilt, Michelle Liu, Salisha Marryshow, Nicole Neville, Natasha Petry, Sidd Pratap, Vernon Sherden, Kimberly Snell, Ana Tomescu, Megan Trietsch, James Walker, Deanna Web, Erin Whiting, Russell A. Wilke, Simona Volpi, Sarah Hutchison, Natalie Kucher, Ebony Madden, Jessica Reinach, Renee Rider, Ismail Safi, Ella Samer, Lori Orlando, Lani Banez, Lisa Bendz, Jackie Jordan, Ann McGee, Christina Nix, Lorraine Vergara, Tyler Colon, Aaishah Francis, Samantha Guagliardo, Najiba Khan, Camila Tan Lam, Michelle Sciarrino, Emma Maiman‐Stadtmauer, Sofia Medina‐Pardo, Ololade (Lola) Williams, Sheng Luo, Kevin Anstrom, Alicia Ellis, Stephen Ellis, Hwasoon Kim, Peter Merrill, Lilin She, Jennifer Shepherd, Saira Siddiqui, Jun Wen, Brittany Davis, John Howard, Alia Jamison, Lydia Joyner, Ellie Kiihne, Johnathan Oliver, Libbie Silverman, Jordan Sonneville Jennifer Stuart, Laurel Tokar, Neil Calman, Daviana Buck, Nicole Canchucaja Porshia Cook, Ariel Jacobs Danielle John, Mirta (Mimi) Milanes, Wambui Ngari, Megan Triestch, Abraham Garcia, Carol Gutierrez, Steven Houtschilt, Maria Lopez, Alan Mejia, Anaite Montes Bu, Deanna Webb, Sonja White, Ali Brewer, Brittni Deadrick, Alexis Meyer, Blair Svennes, Hana Al Alshaykh, Tala Basha, Asia Cobb, Brendon Cooper, Amanda Elchynski, Amanda Elsey, Anuksha Gotmare, Lauren Lemke, Arielle Nelson, Michael Read, Genevieve Rosier, Isabella Schultz, Chiara Chermont Spina, Joshua Terrell, Alexa Valko, Precious Williams, Tracy Leonard, David Smith, Marian Davis, Vincent Guerra, Jennifer Salo, Claudia Cartaya Torres, Jorge Valedon, Paola Nieves Viana, Jose Alonso, Jeffery Gainer, Morgan Howard, Fatoumata Kaba, Brianna Rivers, Liliana Serrano, Kimberly Vigal, ADeia Williams, Angelo Lazaro, Salisha Merryshow, Henry Ong, John Thomas Callaghan, Raheleh Rahimi Darabad, Daniel Getu, Katherine Huber, Judive Jocelyn, Robin Morman Li, Rosalena Muckle, Brandi Plunkett, Siegfried Schmidt, Evgenia Teal, Petra Townsend, Joshua R. Wellington   +255 more
wiley   +1 more source

Cerebrospinal fluid leak from trauma to congenital meningocele of a 40-year-old woman in Korea: a case report [PDF]

Precision and Future Medicine
Intracranial hypotension typically presents with orthostatic headache caused by cerebrospinal fluid (CSF) hypovolemia, most commonly resulting from spontaneous or iatrogenic CSF leaks.
Woojae Myung, Hyun Seok Do, Jae Rim Kim, Mi Ji Lee, Eugene Lee   +4 more
doaj   +1 more source

Modifiable Transdiagnostic Risk and Protective Factors as Potential CBT Augmentation Targets for Eating Disorders: An Updated Umbrella Review

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective A focus on transdiagnostic targets is one of the key strategies for developing effective, efficient, and scalable treatments for mental health conditions. We conducted an umbrella review of recent meta‐analyses (August 2022 to May 2026) to update our understanding of critical transdiagnostic intervention targets that could inform ...
Yuan Zhou, Marcela Radunz, Tracey D. Wade   +2 more
wiley   +1 more source

Structural and Functional Brain Alterations in Post-traumatic Headache Attributed to Mild Traumatic Brain Injury: A Narrative Review

Frontiers in Neurology, 2019
Introduction: By definition, post-traumatic headache (PTH) attributed to mild traumatic brain injury (mTBI) is not associated with brain structural abnormalities that are seen on routine clinical inspection of brain images.
Todd J. Schwedt
doaj   +1 more source

Post-dural puncture headache

, 2012
Ahmed Ghaleb1, Arjang Khorasani2, Devanand Mangar31Department of Anesthesiology, University of Arkansas for Medical Sciences, Little Rock, AR, 2Anesthesiology Residency Program, Advocate Illinois Masonic Medical Center, Chicago, IL, 3Florida Gulf to Bay ...
Ahmed Ghaleb, Khorasani A, Mangar D, Ghaleb A, null Khorasani, null Mangar   +5 more
core   +1 more source

Reflex seizures and epilepsy surgery: A network approach case‐based exploration

Epileptic Disorders, EarlyView.
Abstract Context Reflex seizures (RS) are defined by their consistent provocation by specific stimuli, encompassing a broad range from elementary sensory inputs to complex cognitive tasks. While RS are often encountered in clinical practice, their surgical management remains sparsely reported and poorly systematized.
Olivier Aron, Laure Salmon, Nicolas Nguyen, Dènahin Toffa, Sami Obaid, Alexis Robin, Dang Khoa Nguyen   +6 more
wiley   +1 more source

Supplemental Material, Child_Neurology_Society_Survey_of_Practitioners_on_Management_of_Pediatric_Post-traumatic_Headache_(PTH) - Survey of Child Neurologists on Management of Pediatric Post-traumatic Headache

, 2019
Supplemental Material, Child_Neurology_Society_Survey_of_Practitioners_on_Management_of_Pediatric_Post-traumatic_Headache_(PTH) for Survey of Child Neurologists on Management of Pediatric Post-traumatic Headache by Rachel Pearson, Desiree Levyim, Meeryo ...
Meeryo Choe (6875474), Rachel Pearson (6875468), Desiree Levyim (6875471), Raquel Langdon (6875480), Sharief Taraman (6875477)   +4 more
core   +1 more source

Long‐term prediction of epilepsy following traumatic brain injury among veterans using routine clinical data

Epilepsia, EarlyView.
Abstract Objective Despite elevated risk for epilepsy following traumatic brain injury (TBI), there are limited tools to assess epilepsy risk following TBI using routine clinical data. The objective of this study was to develop and validate a machine learning approach to predict the onset of posttraumatic epilepsy (PTE) over varying time horizons ...
Mustafa Ozmen, Shashank Vadlamani, James J. Gugger, Megan Amuan, Ramon Diaz‐Arrastia, Mary Jo Pugh, Eamonn Kennedy   +6 more
wiley   +1 more source

Brain‐wide magnetic resonance imaging analysis of neurobehavioral comorbidities in temporal lobe epilepsy

Epilepsia, EarlyView.
Abstract Objective In temporal lobe epilepsy (TLE), patients often present with neurobehavioral comorbidities encompassing affective and cognitive difficulties. Whereas the latter have been related to atypical connectivity of mesiotemporal and frontotemporal circuits, the brain basis of affective symptoms remains incompletely understood.
Fatemeh Fadaie, Benoit Caldairou, Boris C. Bernhardt, Andrea Bernasconi, Neda Bernasconi   +4 more
wiley   +1 more source

Synergistic Trigeminal Pain Molecules in a Model of Traumatic Brain Injury: Implications for Post-Traumatic Headache [PDF]

, 2015
Introduction Headache following traumatic brain injury (TBI) is highly prevalent, and also the most common and persistent symptom of post-concussion syndrome [1,2].
Elliott, PhD., Melanie B., Clark, MD, Shannon W., Daiutolo, Brittany V., Tyburski, Ashley L.   +3 more
core   +1 more source