Results 81 to 90 of about 13,226,587 (254)
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Posted Prices and Bid Affiliation: Evidence from Experimental Auctions [PDF]
In most experimental auctions, researchers ask participants to bid on the same item in multiple potentially binding rounds, posting the price submitted by the top bidder or bidders after each of those rounds.
Jay R. Corrigan, Matthew C. Rousu
core
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
International Journal of Qualitative MethodsAdolescent research concerning sensitive topics presents unique challenges due to the complexities of navigating ethical considerations and establishing trust within this population.
Alex Sandro Gomes Pessoa +4 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Ines Wagner: Workers without Borders. Posted Work and Precarity in the EU
Norsk Sosiologisk Tidsskrift, 2020 Line Eldring
doaj +1 more source
Chronology of the Myitsone Dam at the Confluence of Rivers above Myitkyina
Journal of Current Southeast Asian Affairs, 2012 This chronology incorporates very significant material related to 2002–2010, posted on the web by “ipea-editor” on 17 January 2011, down-loaded 26 October 2011. Efforts continue to contact that person/group to acknowledge their work. Note that quotations
Editor's Appendix
doaj
Visualization of the 2017 #EURegionsWeek on Twitter
Regional Studies, Regional Science, 2018 The European Week of Regions and Cities gathered almost 6000 participants from all over Europe in Brussels on 9–12 October 2017 to investigate how regions and cities can work for a better future in Europe.
Claudio Nichele
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source