Posterior Cingulate Cortex Network Predicts Alzheimer's Disease Progression [PDF]
Frontiers in Aging Neuroscience, 2020 Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by the accumulation of toxic misfolded proteins, which are believed to have propagated from disease-specific epicenters through their corresponding large-scale structural ...
Pei-Lin Lee +13 more
doaj +7 more sources
Uncovering a tripartite landmark in posterior cingulate cortex. [PDF]
Sci Adv, 2022 Understanding brain structure-function relationships, and their development and evolution, is central to neuroscience research. Here, we show that morphological differences in posterior cingulate cortex (PCC), a hub of functional brain networks, predict ...
Willbrand EH +11 more
europepmc +6 more sources
Cognitive Control Signals in Posterior Cingulate Cortex [PDF]
Frontiers in Human Neuroscience, 2010 Efficiently shifting between tasks is a central function of cognitive control. The role of the default network—a constellation of areas with high baseline activity that declines during task performance—in cognitive control remains poorly understood.
Benjamin eHayden +2 more
doaj +5 more sources
Age Influences Loss Aversion Through Effects on Posterior Cingulate Cortical Thickness [PDF]
Frontiers in Neuroscience, 2021 Decision-making strategies shift during normal aging and can profoundly affect wellbeing. Although overweighing losses compared to gains, termed “loss aversion,” plays an important role in choice selection, the age trajectory of this effect and how it ...
Zoe R. Guttman +7 more
doaj +3 more sources
The human posterior cingulate, retrosplenial, and medial parietal cortex effective connectome, and implications for memory and navigation. [PDF]
Hum Brain Mapp, 2023 The human posterior cingulate, retrosplenial, and medial parietal cortex are involved in memory and navigation. The functional anatomy underlying these cognitive functions was investigated by measuring the effective connectivity of these Posterior ...
Rolls ET +4 more
europepmc +2 more sources
Posterior cingulate cortex targeted real-time fMRI neurofeedback recalibrates functional connectivity with the amygdala, posterior insula, and default-mode network in PTSD. [PDF]
Brain Behav, 2023 Alterations within large‐scale brain networks—namely, the default mode (DMN) and salience networks (SN)—are present among individuals with posttraumatic stress disorder (PTSD).
Lieberman JM +12 more
europepmc +2 more sources
Posterior cingulate cortex reveals an expression profile of resilience in cognitively intact elders. [PDF]
Brain Commun, 2022 The posterior cingulate cortex, a key hub of the default mode network, underlies autobiographical memory retrieval and displays hypometabolic changes early in Alzheimer disease.
Kelley CM +4 more
europepmc +2 more sources
Correlation between hippocampal volumes and proton magnetic resonance spectroscopy of the posterior cingulate gyrus and hippocampi in Alzheimer's disease [PDF]
Dementia & Neuropsychologia, 2010 Prior studies have reported hippocampal volume loss, decrease in N-Acetylaspartate (NAA) concentration and increased myo-inositol (mI) concentration in patients with Alzheimer's disease (AD).
Eun Joo Park +5 more
doaj +2 more sources
Poor sleep accelerates hippocampal and posterior cingulate volume loss in cognitively normal healthy older adults. [PDF]
J Sleep Res, 2022 Poor sleep quality is a known risk factor for Alzheimer’s disease. This longitudinal imaging study aimed to determine the acceleration in the rates of tissue loss in cognitively critical brain regions due to poor sleep in healthy elderly individuals ...
Liu C +5 more
europepmc +2 more sources
Frontiers in Human Neuroscience, 2018 The retrosplenial cortex has long been implicated in human spatial orientation and navigation. However, neural activity peaks labeled “retrosplenial cortex” in human neuroimaging studies investigating spatial orientation often lie significantly outside ...
Ford Burles +4 more
doaj +2 more sources