Results 111 to 120 of about 126,420 (329)

Neurodevelopmental Changes in Social Reinforcement Processing: A Functional Magnetic Resonance Imaging Study. [PDF]

, 2017
ObjectiveIn the current study we investigated neurodevelopmental changes in response to social and non-social reinforcement.MethodsFifty-three healthy participants including 16 early adolescents (age, 10-15 years), 16 late adolescents (age, 15-18 years),
Blair, James, Bookheimer, Susan Y, Hwang, Soonjo, Meffert, Harma, Sinclair, Stephen, VanTieghem, Michelle R, White, Stuart F   +6 more
core   +2 more sources

Neuroinflammation in GAD65 Antibody‐Associated Epilepsy Measured Using [18F]DPA‐714 PET/MRI

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The timing for initiating immunotherapy in patients with glutamic acid decarboxylase 65 (GAD65) antibody‐associated epilepsy is a challenge. We used the translocator protein radioligand [18F]DPA‐714 and PET to evaluate brain microglial activation.
Jingjing Chen, Yuying Zhang, Heyu Zhang, Jinming Zhang, Ningning Wang, Xintong Guo, Yicong Liu, Yue Liu, Xiangsong Zhang, Ziyi Chen, Guanzhong Ni   +10 more
wiley   +1 more source

Brain microvascular calcification is increased in human donors with dementia compared to elderly controls: a pilot study

Frontiers in Aging Neuroscience
IntroductionIntracranial vascular calcification has been observed in the setting of both Alzheimer's disease (AD) and vascular dementia. Increased calcification in intracranial and extracranial arteries is associated with an increased risk of dementia ...
Kelly A. Borges, Isabelle Lombardi, Mackenzie Sivilli, Joseph Aabye, Isabella Romano, Saud A. Nasruddin, Mugdha V. Padalkar, Daniel Moussouros, Olga V. Savinova   +8 more
doaj   +1 more source

Posterior Cingulate Neurons Dynamically Signal Decisions to Disengage during Foraging [PDF]

Neuron, 2017
Foraging for resources is a fundamental behavior balancing systematic search and strategic disengagement. The foraging behavior of primates is especially complex and requires long-term memory, value comparison, strategic planning, and decision-making. Here we provide evidence from two different foraging tasks that neurons in primate posterior cingulate
David L, Barack, Steve W C, Chang, Michael L, Platt   +2 more
openaire   +2 more sources

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

Significant correlation between openness personality in normal subjects and brain myelin mapping with T1/T2-weighted MR imaging

Heliyon, 2017
Background: The objective of this study was to examine the relationship between the myelination and the psychological trait of openness to experience in young cognitively normal volunteers using regional T1-weighted (T1w)/T2w ratios on magnetic resonance
Fumihiko Yasuno, Takashi Kudo, Akihide Yamamoto, Kiwamu Matsuoka, Masato Takahashi, Hidehiro Iida, Masafumi Ihara, Kazuyuki Nagatsuka, Toshifumi Kishimoto   +8 more
doaj   +1 more source

Neural responses to facial and vocal expressions of fear and disgust [PDF]

, 1998
Neuropsychological studies report more impaired responses to facial expressions of fear than disgust in people with amygdala lesions, and vice versa in people with Huntington's disease.
A. J. Calder, A. W. Young, C. Andrew, E. T. Bullmore, J. A. Gray, Lane R. D., M. Brammer, M. L. Phillips, Paradiso S., S. C. R. Williams, S. K. Scott, V. Giampietro   +11 more
core   +2 more sources

Ultrasound in Women's Health: Mechanisms, Applications, and Emerging Opportunities

Advanced Materials, EarlyView.
As healthcare moves toward decentralization, ultrasound technologies are evolving from strictly imaging tools in clinical settings into versatile diagnostic and therapeutic platforms, with growing roles addressing women's health needs. This review highlights how ultrasound's underlying physical mechanisms can be harnessed to reduce disparities in women'
Sarah B. Ornellas, Bilal Kizilaslan, Aastha Shah, Jason F. Hou, Yoonsoo Shin, Alejandra Hernandez Moyers, Claudia Lozano, Canan Dagdeviren   +7 more
wiley   +1 more source

Altered resting-state connectivity in subjects at ultra-high risk for psychosis: an fMRI study

Behavioral and Brain Functions, 2010
Background Individuals at ultra-high risk (UHR) for psychosis have self-disturbances and deficits in social cognition and functioning. Midline default network areas, including the medial prefrontal cortex and posterior cingulate cortex, are implicated in
Choi Jung-Seok, Park Hye-Yoon, Kim Euitae, Choi Chi-Hoon, Jang Joon, Jung Wi, Oh Jungsu S, Shim Geumsook, Jung Myung, Kwon Jun   +9 more
doaj   +1 more source

Change detection in children with autism: an auditory event-related fMRI study [PDF]

, 2006
Autism involves impairments in communication and social interaction, as well as high levels of repetitive, stereotypic and ritualistic behaviours, and extreme resistance to change. This latter dimension, whilst required for a diagnosis, has received less
Ashwin, C, Baron-Cohen, S, Belmonte, MK, Bernard, FA, Bullmore, ET, Davis, MH, Gomot, M   +6 more
core   +1 more source