Results 141 to 150 of about 871,457 (367)

Sex Differences in Associations of Lewy Body Disease with Alzheimer's Disease and Cognitive Decline

Annals of Neurology, EarlyView.
Objective To investigate how sex and age at menopause influence the interplay between Alzheimer's disease (AD) and Lewy body disease (LBD) neuropathologies, and their associations with cognitive decline. Methods We analyzed data from: (1) three Rush Alzheimer's Disease Center cohorts (i.e., the Religious Orders Study, Rush Memory and Aging Project, and
Madeline Wood Alexander, D. Luke Fischer, Lawren VandeVrede, Emma Nichols, Lei Yu, James R. Pike, Walter Swardfager, Che‐Yuan Wu, Mario Masellis, Liisa A. M. Galea, Katherine Zukotynski, Gillian Einstein, Sandra E. Black, Lisa L. Barnes, Julie A. Schneider, Zoe Arvanitakis, Kaitlin B. Casaletto, Jennifer S. Rabin   +17 more
wiley   +1 more source

Remembering Forward: Neural Correlates of Memory and Prediction in Human Motor Adaptation [PDF]

, 2012
We used functional MR imaging (FMRI), a robotic manipulandum and systems identification techniques to examine neural correlates of predictive compensation for spring-like loads during goal-directed wrist movements in neurologically-intact humans ...
Houk, James, Mosier, Kristine M., Salowitz, Nicole M.G., Scheidt, Robert A., Simo, Lucia, Suminski, Aaron J., Zimbelman, Janice   +6 more
core   +2 more sources

Anterior Versus Posterior Insular Epilepsy: Correlations with Semiology Based on Stereoelectroencephalography

Annals of Neurology, EarlyView.
Objective To characterize insular seizure semiology and correlate with stereoelectroencephalography (SEEG) seizure onset in a well‐defined cohort, in particular examining differences between anterior and posterior insular seizures. Methods We documented all semiological signs and the timing of emergence for 45 patients with SEEG‐confirmed insular ...
Jason Chisholm, Balu Krishnan, Jean Khoury, Andreas Alexopoulos, William Bingaman, Demitre Serletis, Imad Najm, Juan C. Bulacio   +7 more
wiley   +1 more source

Evaluating Methods of Correcting for Multiple Comparisons Implemented in SPM12 in Social Neuroscience fMRI Studies: An Example from Moral Psychology [PDF]

, 2018
In fMRI research, the goal of correcting for multiple comparisons is to identify areas of activity that reflect true effects, and thus would be expected to replicate in future studies.
Glenn, Andrea L., Han, Hyemin
core  

Regional differences in the coupling between resting cerebral blood flow and metabolism may indicate action preparedness as a default state. [PDF]

, 2008
Although most functional neuroimaging studies examine task effects, interest intensifies in the "default" resting brain. Resting conditions show consistent regional activity, yet oxygen extraction fraction constancy across regions.
Alavi, Abass, Greenberg, Joel H, Gur, Raquel E, Gur, Ruben C, Ragland, J Daniel, Reivich, Martin   +5 more
core   +2 more sources

Delirium is not associated with altered hub flexibility of the posterior cingulate cortex

Clinical Neurophysiology, 2018
restriction
van Montfort, S. J.T., Numan, T., van Dellen, E., Kyeong, S., Douw, L., Kim, J. J.   +5 more
openaire   +6 more sources

Protective Effects of Socioeconomic Status and Lifestyle on Amyloid‐ and White Matter Hyperintensity‐Related Longitudinal Brain Atrophy and Cognitive Decline

Annals of Neurology, EarlyView.
Objective Socioeconomic status (SES) and lifestyle activities (LA) are strongly related, and both are associated with dementia risk. We investigated the influence of SES and LA on brain atrophy and cognitive decline considering amyloid‐beta (Aβ) positron emission tomography and white matter hyperintensity (WMH) load.
Dario Bachmann, Maha Wybitul, Sandro Studer, Antje Saake, Katrin Rauen, Andreas Buchmann, Bettina von Rickenbach, Esmeralda Gruber, Roger M. Nitsch, Christoph Hock, Anton Gietl, Valerie Treyer   +11 more
wiley   +1 more source

Mechanisms of cognitive-behavioral therapy for obsessive-compulsive disorder involve robust and extensive increases in brain network connectivity. [PDF]

, 2017
Cognitive-behavioral therapy (CBT) is effective for obsessive compulsive disorder (OCD); however, little is understood about its mechanisms related to brain network connectivity.
Cheng, G, Feusner, JD, Moody, TD, Morfini, F, O'Neill, J, Reggente, N, Sheen, C, Tadayonnejad, R   +7 more
core   +1 more source

Effect of age and the APOE gene on metabolite concentrations in the posterior cingulate cortex

NeuroImage, 2017
Proton magnetic resonance spectroscopy (1H-MRS) has provided valuable information about the neurochemical profile of Alzheimer's disease (AD). However, its clinical utility has been limited in part by the lack of consistent information on how metabolite concentrations vary in the normal aging brain and in carriers of apolipoprotein E (APOE) ε4, an ...
Suri, S, Emir, U, Stagg, CJ, Near, J, Mekle, R, Schubert, F, Zsoldos, E, Mahmood, A, Singh-Manoux, A, Kivimaki, M, Ebmeier, KP, Mackay, CE, Filippini, N   +12 more
openaire   +5 more sources

Mutations in the Key Autophagy Tethering Factor EPG5 Link Neurodevelopmental and Neurodegenerative Disorders Including Early‐Onset Parkinsonism

Annals of Neurology, EarlyView.
Objective Autophagy is a fundamental biological pathway with vital roles in intracellular homeostasis. During autophagy, defective cargoes including mitochondria are targeted to lysosomes for clearance and recycling. Recessive truncating variants in the autophagy gene EPG5 have been associated with Vici syndrome, a severe early‐onset neurodevelopmental
Hormos Salimi Dafsari, Celine Deneubourg, Kritarth Singh, Reza Maroofian, Zita Suprenant, Ay Lin Kho, Neil J Ingham, Karen P Steel, Preethi Sheshadri, Franciska Baur, Lea Hentrich, Birgit Gerisch, Mina Zamani, Cesar Alves, Ata Siddiqui, Haidar S Dafsari, Mehri Salari, Anthony E. Lang, Michael Harris, Alice Abdelaleem, Saeid Sadeghian, Reza Azizimalamiri, Hamid Galehdari, Gholamreza Shariati, Alireza Sedaghat, Jawaher Zeighami, Daniel Calame, Dana Marafi, Ruizhi Duan, Adrian Boehnke, Gary D. Clark, Jill A. Rosenfeld, Carrie A. Mohila, Dora Steel, Saurabh Chopra, Suvasini Sharma, Nicolai Kohlschmidt, Steffi Patzer, Afshin Saffari, Darius Ebrahimi‐Fakhari, Büşra Eser Çavdartepe, Irene J Chang, Erika Beckman, Renate Peters, Andrew Paul Fennell, Bernice Lo, Luisa Averdunk, Felix Distelmaier, Martina Baethmann, Frances Elmslie, Kairit Joost, Sheela Nampoothiri, Dhanya Yesodharan, Hanna Mandel, Amy Kimball, Antonie D. Kline, Cyril Mignot, Boris Keren, Vincent Laugel, Katrin Õunap, Kalpana Devadathan, Frederique M.C. van Berkestijn, Arpana Silwal, Saskia Koene, Sumit Verma, Mohammed Yousuf Karim, Chahynez Boubidi, Majid Aziz, Gehad ElGhazali, Lauren Mattas, Mohammad Miryounesi, Farzad Hashemi‐Gorji, Shahryar Alavi, Nayereh Nouri, Mehrdad Noruzinia, Saeideh Kavousi, Arveen Kamath, Sandeep Jayawant, Russell Saneto, Nourelhoda A. Haridy, Pinar Ozkan Kart, Ali Cansu, Madeleine Joubert, Claire Beneteau, Kyra E. Stuurman, Martina Wilke, Tahsin Stefan Barakat, Homa Tajsharghi, Annarita Scardamaglia, Sadeq Vallian, Semra Hız, Ali Shoeibi, Reza Boostani, Narges Hashemi, Meisam Babaei, Norah Saleh Alsaleh, Julie Porter, Tania Attié‐Bitach, Pauline Marzin, Dorota Wicher, Jessica I. Gold, Elisabeth Schuler, Amna Kashgari, Rakan F. Alanazi, Wafaa Eyaid, Marc Engelen, Mirjam Langeveld, Burkhard Stüve, Yun Li, Gökhan Yigit, Bernd Wollnik, Mariana H.G Monje, Dimitri Krainc, Niccolò E. Mencacci, Somayeh Bakhtiari, Michael Kruer, Emanuela Argilli, Elliott Sherr, Yalda Jamshidi, Ehsan Ghayoor Karimiani, Yiu Wing Sunny Cheung, Ivan Karin, Giovanni Zifarelli, Peter Bauer, Wendy K Chung, James R. Lupski, Manju A. Kurian, Jörg Dötsch, Jürgen‐Christoph von Kleist‐Retzow, Thomas Klopstock, Matias Wagner, Calvin Yip, Andreas Roos, Rita Carsetti, Carlo Dionisi‐Vici, Mathias Gautel, Michael R Duchen, Adam Antebi, Henry Houlden, Manolis Fanto, Heinz Jungbluth   +140 more
wiley   +1 more source