Results 241 to 250 of about 122,744 (337)

Dysregulation of the endosomal sorting complex III is linked to neurodegeneration in progressive multiple sclerosis

open access: yesBrain Pathology, EarlyView.
This study shows that components of the ESCRT‐III membrane repair machinery, VPS4B and CHMP2A, are dysregulated in progressive MS and are associated with higher neurodegeneration and inflammation. This might lead to improper function of the complex to inhibit the final stages of necroptosis activation and thus impede neuronal cell death.
Carmen Picon   +5 more
wiley   +1 more source

The impact of PICALM genetic variations on reserve capacity of posterior cingulate in AD continuum

open access: gold, 2016
Wei Xu   +99 more
openalex   +1 more source

A unified 3D reconstruction of microscopy and MRI in a brain showing Alzheimer's disease‐related neuropathology

open access: yesBrain Pathology, EarlyView.
Post mortem MRI was combined with neuropathological assessments at 600 μm intervals throughout the brain. Through this approach, a three dimensional account of an entire human brain with an intermediate Alzheimer's disease neuropathologic change was created.
Anneke Alkemade   +13 more
wiley   +1 more source

Posterior cingulate cortex hyperactivity in conversion disorder: a PET/MRI study. [PDF]

open access: yesFront Psychiatry
Tatlı SZ   +5 more
europepmc   +1 more source

Psilocybin as a novel treatment for chronic pain

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Psychedelic drugs are under active consideration for clinical use and have generated significant interest for their potential as anti‐nociceptive treatments for chronic pain, and for addressing conditions like depression, frequently co‐morbid with pain.
Tate Askey   +3 more
wiley   +1 more source

Independent replications reveal anterior and posterior cingulate cortex activation underlying state anxiety-attenuated face encoding. [PDF]

open access: yesCommun Psychol
Buehler SK   +13 more
europepmc   +1 more source

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