Causal links between blood inflammation markers and postherpetic neuralgia risk: insights from a two-sample Mendelian randomization study [PDF]
IntroductionPrevious studies have suggested an association between blood inflammation-related factors and postherpetic neuralgia. However, the causal relationship between blood inflammation-related factors and postherpetic neuralgia remains unclear ...
Yu Wang, Tian Jia
doaj +3 more sources
Predictors of Postherpetic Neuralgia: A Prospective Study From Eastern Nepal. [PDF]
ABSTRACT Background Herpes zoster (HZ) is a viral infection with severe acute and chronic pain. This study was aimed at determining the incidence rate of postherpetic neuralgia (PHN). The objectives of the study were to understand the epidemiology of HZ and to identify the risk factors for PHN at a referral hospital in eastern Nepal.
Marahatta S, Jha SK, Ghimire A.
europepmc +2 more sources
Comparison of Duloxetine Supplemented With Pregabalin and Amitriptyline Supplemented With Pregabalin for the Treatment of Postherpetic Neuralgia: A Double-Blind, Randomized Crossover Trial. [PDF]
This is a double‐blind, randomized, crossover trial involving PHN patients. The purpose of this study is to compare the efficacy and tolerability of duloxetine combined with pregabalin and amitriptyline combined with pregabalin in the treatment of PHN, as well as their impact on sleep and quality of life in patients with PHN.
Wang Y+9 more
europepmc +2 more sources
Contemporary management of pain in cirrhosis: Toward precision therapy for pain
Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman+4 more
wiley +1 more source
Abstract Background Patients with pudendal neuralgia (PN) experience long‐lasting chronic pain, hyperalgesia, and comorbid emotional disorders, such as depression and anxiety. Treatment via conventional pulsed radiofrequency (PRF) current carries a significantly high rate of failure.
Cheng‐Long Wang, Tao Song
wiley +1 more source
Abstract Objective Trigeminal postherpetic neuralgia (PHN) is often refractory to treatment. Pulsed radiofrequency (PRF) neuromodulation can help in preventing PHN after herpes zoster. This study aimed to compare the efficacy and safety of two different PRF modes on gasserian ganglion neuromodulation in elderly patients with acute/subacute trigeminal ...
Cheng‐Fu Wan, Tao Song
wiley +1 more source
A systematic review and meta-analysis of risk factors for postherpetic neuralgia. [PDF]
Patients with herpes zoster can develop persistent pain after rash healing, a complication known as postherpetic neuralgia. By preventing zoster through vaccination, the risk of this common complication is reduced.
Bhaskaran, Krishnan+6 more
core +1 more source
Quantification of risk factors for postherpetic neuralgia in herpes zoster patients: A cohort study. [PDF]
OBJECTIVE: To investigate risk factors for postherpetic neuralgia, the neuropathic pain that commonly follows herpes zoster. METHODS: Using primary care data from the Clinical Practice Research Datalink, we fitted multivariable logistic regression models
Bhaskaran, Krishnan+7 more
core +1 more source
Ultrasound-guided supraorbital radiofrequency ablation for V1 postherpetic neuralgia
Postherpetic neuralgia (PHN) affecting the first division of the trigeminal nerve (TrN) (V1) is a difficult to manage condition, characterized by neuropathic symptoms such as burning sensation, allodynia, and hyperalgesia that continues even after the ...
Victor M Silva-Ortiz+5 more
doaj +1 more source
Varicella-Zoster viruses associated with post-herpetic neuralgia induce sodium current density increases in the ND7-23 Nav-1.8 neuroblastoma cell line [PDF]
Post-herpetic neuralgia (PHN) is the most significant complication of herpes zoster caused by reactivation of latent Varicella-Zoster virus (VZV). We undertook a heterologous infection in vitro study to determine whether PHN-associated VZV isolates ...
A Vafai+44 more
core +3 more sources