Results 31 to 40 of about 7,072 (179)

Analgesic and Neurorestorative Effects of αO-Conotoxin GeXIVA[1,2] in Diabetic Neuropathic Pain and Postherpetic Neuralgia

Toxins
Chronic neuropathic pain, particularly diabetic neuropathic pain and postherpetic neuralgia, severely impairs patients’ quality of life due to their complex mechanisms and recurrent, long-term nature, making treatment challenging.
Rongyan He, Shuting Xiao, Xiaoying Liang, Qiuyu Cao, Shaoxian Wu, Sulan Luo   +5 more
doaj   +1 more source

Activation and expression of μ-calpain in dorsal root contributes to RTX-induced mechanical allodynia

Molecular Pain, 2017
Background Calpain is a calcium-dependent cysteine protease, and inhibition of calpain by pre-treatment with MDL28170 attenuated the rat mechanical allodynia in a variety of pain models. Postherpetic neuralgia (Shingles) is a neuropathic pain conditioned
Xiao-Cui Yuan, Cai-Hua Wu, Fang Gao, Hong-Ping Li, Hong-Chun Xiang, He Zhu, Xiao-Li Pan, Li-Xue Lin, Yan-Shen Liu, Wei Yu, Bo Tian, Xian-Fang Meng, Man Li   +12 more
doaj   +1 more source

Acyclovir and postherpetic neuralgia

Biomedicine & Pharmacotherapy, 1990
Studies have demonstrated the benefit of acyclovir, given intravenously or orally, on the acute illness in herpes zoster (HZ). Whether or not such treatment influences the subsequent development of postherpetic neuralgia (PHN) has been the subject of recent controversy.
Klenerman, P, Luzzi, G
openaire   +3 more sources

Distinct effects of fibromyalgia pain, depression and anxiety on perception of affective touch and pain

The Journal of Physiology, EarlyView.
Abstract figure legend Patients with fibromyalgia (FM) and no‐pain controls completed questionnaire‐based ratings of chronic pain, childhood trauma, anxiety and depression. Brief touch stimuli were then administered, including slow brushing at the C‐tactile optimal velocity of 3 cm/s, deep oscillating pressure with a compression sleeve, roboticized ...
Benedetta Albinni, Marisa Zimmerman, Vincent Alasha, Jacob Ross, Lindsey Crankshaw, Sandy R. Hu, Nathaniel Schuster, Laura Case   +7 more
wiley   +1 more source

Retrogasserian Glycerol Rhizotomy (RGGR) for Trigeminal Neuralgia Induced by Postvaccination Herpetic Reactivation: A Rare Case Report

Clinical Case Reports
Reports on surgical treatment for postherpetic trigeminal neuralgia after COVID vaccination have not been found in the literature. Here, we described a case of postherpetic trigeminal neuralgia after COVID vaccination that was treated with percutaneous ...
M. Kodeeswaran, M. Naveen Kumar, K. P. Priyadharshan, Arun Narinder, M. Panchabakesan, B. C. Suresh Kumar, Bipin Chaurasia   +6 more
doaj   +1 more source

The management of postherpetic neuralgia [PDF]

Postgraduate Medical Journal, 1997
Summary Postherpetic neuralgia is defined as pain persisting, or recurring, at the site of shingles at least three months after the onset of the acute rash. Thus defined, at least half of shingles sufferers over the age of 65 years develop postherpetic neuralgia. In addition to increasing age, less important risk factors for postherpetic
openaire   +2 more sources

Burden and Treatment Preference of Probable Neuropathic Pain in 13 592 people: A Cross‐Sectional and Discrete Choice Experiment in the General Population in Malaysia

Journal of the Peripheral Nervous System, Volume 31, Issue 3, September 2026.
ABSTRACT Background and Aim Neuropathic pain (NeuP) is widely underdiagnosed, and treatment‐related adverse events often drive nonadherence. We investigated the probable NeuP prevalence, symptoms recognition, and treatment preferences among the general population in Malaysia.
Wee‐Kiat Tan, Maznah Dahlui, Azhari Rosman, Hiang Leng Tan, Noraidah Guntalib, Siew Pheng Chan, Shalini Sree Dharan, Pei Chiek Teh, Daniel Yi Jie Wong, Kenny Tan, Solomon Tesfaye, Lee‐Ling Lim   +11 more
wiley   +1 more source

Postherpetic neuralgia: epidemiology, pathophysiology, and pain management pharmacology

Journal of Multidisciplinary Healthcare, 2016
Theresa Mallick-Searle,1 Brett Snodgrass,2 Jeannine M Brant,3 1Pain Management Center, Stanford Health Care, Redwood City, CA, 2LifeLinc Pain Centers, Cordova, TN, 3Billings Clinic, Billings, MT, USA Abstract: Herpes zoster, also known as shingles, is a ...
Mallick-Searle T, Snodgrass B, Brant JM
doaj  

Postherpetic Neuralgia: Mechanisms, Risk Factors, and Stratified Management—A Narrative Review

CNS Neuroscience &Therapeutics, Volume 32, Issue 7, July 2026.
The incidence of PHN is increasing, posing a substantial public health burden. Its pathogenesis involves VZV reactivation, peripheral and central sensitization, and genetic susceptibility, with key risk factors including older age, severe acute pain, extensive rash, immunocompromise, comorbidities, and delayed treatment.
Fei Tang, Fukun Zhao
wiley   +1 more source

TrkA abundance is increased in cutaneous nerves in bortezomib‐induced neuropathy

Brain Pathology, Volume 36, Issue 4, July 2026.
Cutaneous nerves in bortezomib‐induced peripheral neuropathy (BIPN) show reduced nerve fiber density, increased TrkA expression, and enhanced dermal angiogenesis, highlighting a pathological switch in NGF/TrkA signaling that may contribute to nerve damage and pain. Abstract Tropomyosin receptor kinase A (TrkA), a high‐affinity receptor for nerve growth
Yuying Jin, Nadine Cebulla, Daniel Schirmer, Eva Runau, Leon Flamm, Calvin Terhorst, Laura Jähnel, Johanna Güse, Nicola Giordani, Annett Wieser, Julian Brennecke, Annemarie Sodmann, Martin Kortüm, Robert Blum, Claudia Sommer   +14 more
wiley   +1 more source