Results 61 to 70 of about 21,353 (254)
Clinical Endocrinology, EarlyView.ABSTRACT Background Differentiated thyroid carcinoma (DTC) is typically managed surgically with favourable outcomes. However, surgery may have dire consequences when the tumour invades critical structures. Neoadjuvant therapy with tyrosine kinase inhibitors (TKIs) has emerged as a potential strategy to improve resectability and reduce morbidity in ...
Alexandra Dorman +15 more
wiley +1 more source
Pharmacy Practice, 2006 Objective: The objective of this study was to identify problems in the approval, pharmacovigilance, and post-approval regulatory decision-making procedures involving gefitinib and to propose countermeasures to prevent further drug-induced suffering in ...
Nishimura T, +5 more
doaj
Hallucinatory Side Effects of ADHD Drugs
Pediatric Neurology Briefs, 2009 Clinical trial and postmarketing surveillance data for drugs used in treatment of attention deficit hyperactivity disorder were analyzed to determine the frequency of hallucinations and other psychotic side effects, in a study at the US Food and Drug ...
J Gordon Millichap
doaj +1 more source
Enhancing postmarketing surveillance: continuing challenges [PDF]
British Journal of Clinical Pharmacology, 2015 In this issue, Zeitoun and colleagues 1 examined whether any relationship existed between the speed of European Medicines Agency (EMA) regulatory review of 161 medicines between 2001 and 2010 and reported postmarket safety events; they found no relevant correlation.
Dustin D, French +2 more
openaire +2 more sources
The role of health technology assessment bodies in shaping drug development. [PDF]
, 2017 This is the final version of the article. Available from the publisher via the DOI in this record.The use of health technology assessment (HTA) to inform policy-making is established in most developed countries.
Ciani, O, Jommi, C
core +1 more source
The Rising Misuse of Pharmacovigilance Reporting Systems: A Threat to Evidence‐Based Medicine
Clinical Pharmacology &Therapeutics, Volume 119, Issue 2, Page 318-321, February 2026.In recent years, different national and international regulatory authorities, notably the FDA, have made their adverse event repositories publicly available, offering user‐friendly dashboards. This has led to a large increase in low‐quality, poorly reported research using adverse event reporting databases (e.g., FDA’s Adverse Event Reporting System ...
Charles Khouri +7 more
wiley +1 more source
Current Trends in Duchenne Muscular Dystrophy Research and Therapy: 3D Cardiac Modelling
Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.ABSTRACT Duchenne muscular dystrophy (DMD), caused by dystrophin deficiency, presents a multifaceted challenge that affects both skeletal muscle function and cardiomyocyte homeostasis, causing progressive degeneration and life‐threatening cardiac complications by adolescence.
Marta Przymuszała +3 more
wiley +1 more source
Incomplete Resolution of Deep Vein Thromboses during Rivaroxaban Therapy. [PDF]
, 2017 We present the case of a patient with a deep vein thrombosis (DVT) who failed rivaroxaban therapy. Our patient initially presented with left lower extremity edema, erythema, and pain.
Adashek, Jacob +6 more
core +5 more sources
Andrology, Volume 14, Issue 2, Page 466-479, February 2026.Abstract Objectives This study aimed to evaluate the pharmacodynamic effects of administering tunodafil hydrochloride with alcohol on blood pressure and heart rate in healthy Chinese males, and to investigate the mutual pharmacokinetic interactions and safety of the combination.
Dingyuan Hu +18 more
wiley +1 more source
International Journal of Circumpolar Health, 2020 Background: The incidence of TB among Inuit is the highest in Canada. A significantly shorter latent TB infection (LTBI) treatment with rifapentine and isoniazid once weekly for 12 weeks (3HP) is now available in limited settings in Canada.
G. G. Alvarez +15 more
doaj +1 more source