Results 71 to 80 of about 19,507 (228)
A nationwide survey on patient's versus physician's evaluation of biological therapy in rheumatoid arthritis in relation to disease activity and route of administration : the Be-Raise study [PDF]
, 2016 Objectives : Biological treatment of rheumatoid arthritis (RA) is one of the cornerstones of current treatment strategies for the disease. Surprisingly little information exists on whether the route of administration affects patients' treatment ...
Bert Vander Cruyssen +7 more
core +4 more sources
Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.ABSTRACT While the efficacy of canakinumab, an anti‐interleukin‐1β monoclonal antibody, is well‐established, its safety profile, particularly across different age groups, remains inadequately explored. Using the FDA Adverse Event Reporting System (FAERS) database, this study evaluated postmarketing safety by analyzing adverse event (AE) reports from ...
Youyang Wang +3 more
wiley +1 more source
Safety aspects of infliximab in inflammatory bowel disease patients - A retrospective cohort study in 100 patients of a German University Hospital [PDF]
, 2004 Background: Infliximab, a chimeric anti-tumour necrosis factor monoclonal antibody with potent anti-inflammatory effects, represents an effective treatment option in patients with severe inflammatory bowel disease (IBD).
Ali Y +11 more
core +1 more source
Clinical Pharmacology &Therapeutics, Volume 119, Issue 5, Page 1179-1194, May 2026.Maternal health remains a critical global concern, particularly in underserved populations and in low‐ and middle‐income countries where access to safe and effective therapeutics is limited. Despite the use of medications by most women during pregnancy, the exclusion of pregnant and lactating women from clinical trials has resulted in significant data ...
Rachel K. Scott +7 more
wiley +1 more source
Postmarketing Studies: Benefits and Risks
Value in Health, 1999 To consider the benefits and risks of large postmarketing outcomes studies, as demonstrated by studies of the statin drugs.Literature review.The risks were that the statin studies had a strong coat-tail effect. Each new study was beneficial to all statins as well as the one studied.
Garfield, Frances B., Caro, J. Jaime
openaire +2 more sources
EDDA Study Designs Taxonomy (version 2.0) [PDF]
, 2016 The EDDA Study Designs Taxonomy (v2.0) was developed by the Evidence in Documents, Discovery, and Analytics (EDDA) Group: Tanja Bekhuis (Principal Scientist); Eugene Tseytlin (Systems Developer); Ashleigh Faith (Taxonomist); Faina Linkov (Epidemiologist).
Bekhuis, Tanja, Tseytlin, Eugene
core +1 more source
Clinical Pharmacology &Therapeutics, Volume 119, Issue 5, Page 1350-1361, May 2026.Regional differences in approved drug dosages and administration are shaped by complex factors, including clinical data, prior regulatory decisions, and region‐specific considerations. This study investigated how such factors are associated with variations in approved doses across the United States Food and Drug Administration (FDA), European Medicines
Sachiko Mita, Shunsuke Ono
wiley +1 more source
The FDA, Preemption, and Public Safety: Antiregulatory Effects and Maddening Inconsistency [PDF]
, 2011 Most people think of preemption as a technical constitutional doctrine, but it is pivotally important to health and safety, while also opening the door to broad judicial discretion.
Gostin, Lawrence O.
core +1 more source
Atypical antipsychotic therapy in Parkinson's disease psychosis: A retrospective study. [PDF]
, 2017 ObjectiveParkinson's disease psychosis (PDP) is a frequent complication of idiopathic Parkinson's disease (iPD) with significant impact on quality of life and association with poorer outcomes.
Bizzarri +29 more
core +2 more sources
Adverse Events of Saffron (Crocus sativus L.): Systematic Review of Current Evidence
Health Science Reports, Volume 9, Issue 5, May 2026.ABSTRACT Background Crocus sativus L., commonly known as saffron, is a widely used spice with a rich history of culinary and medicinal applications. This systematic review aims to compile human data from studies on monopreparations of C. sativus, including stigma powder and other extracts, to evaluate their safety.
Fatemeh Sadat Hasheminasab +3 more
wiley +1 more source