Indications and Efficacy of Progestogen‐Monotherapy as Menopause Hormone Therapy: A Narrative Review
ABSTRACT Menopausal hormone therapy (MHT) remains the most effective treatment for vasomotor symptoms (VMS) and other manifestations of menopause; however, its use is limited in women with contraindications to oestrogen. Progestogen monotherapy, though historically underutilized, represents a viable alternative in this population. This narrative review
Chloe Thomas +3 more
wiley +1 more source
ABSTRACT Objective To determine whether vaginal oestrogen therapy improves outcomes after prolapse surgery in postmenopausal women. Design Double‐blind, randomised, placebo‐controlled trial with 12 month follow‐up. Setting Multicentre, 22 hospitals in the Netherlands.
Eva V. Vodegel +25 more
wiley +1 more source
The FGF23/α-Klotho Axis in Postmenopausal Osteoporosis: Associations with Bone Mineral Density and Diagnostic Discrimination. [PDF]
Karalok MH +3 more
europepmc +1 more source
Abstract Diffuse cranial vault hyperostosis is an uncommon finding and may present a diagnostic challenge in clinical and forensic practice. We report the case of a 53‐year‐old woman with a long‐standing history of epilepsy treated with phenytoin and sodium valproate who collapsed at home suddenly and died despite resuscitative efforts.
Maria Piagkou +7 more
wiley +1 more source
Estimated prevalence of osteoporosis in postmenopausal women in Saudi Arabia: A multicenter cross-sectional study. [PDF]
Hakim NA, Hussein KS.
europepmc +1 more source
Systemic Therapy Management Strategies for Early‐Stage Breast Cancer in Australia
Advances in systemic therapy for early‐stage breast cancer in Australia highlight genomic‐guided decisions, subtype‐specific strategies, and emerging targeted and immunotherapies, shaping personalized and de‐escalated treatment approaches. ABSTRACT Breast cancer is the most common cancer among Australian women, with early‐stage disease (Stages I, II ...
Nicholas Zdenkowski +6 more
wiley +1 more source
Associations of General and Central Obesity with Cardiovascular Risk by Menopausal and MASLD Status. [PDF]
Kim DY, Lee KN, Han KD, Kim BK.
europepmc +1 more source
Evidence‐informed recommendations emphasize the integration of CDK4/6 inhibitors with endocrine therapy as a central component in the management of HR+/HER2− advanced breast cancer in Indonesia. Expanding access and facilitating integration within national treatment frameworks are crucial to improve outcomes and reduce disparities in care.
Sonar Soni Panigoro +9 more
wiley +1 more source
Determinants of Immunoglobulin‐G N‐Glycan Patterns in the Aging General Population
The effect of demographic and lifestyle factors on IgG N‐glycosylation, which determines IgG's inflammatory response, remains poorly characterized. Aging, higher BMI, female sex, smoking, and heavy alcohol consumption are determinants of IgG N‐glycome patterns, which are indicative of inflammation. Women exhibit a distinct change in IgG N‐glycosylation
Samantha Leonard +10 more
wiley +1 more source
A Pilot Study of Brain Metabolites and Their Diagnostic Cutoff Point in Postmenopausal Women With Cognitive Impairment Using Magnetic Resonance Spectroscopy. [PDF]
Chen X +9 more
europepmc +1 more source

