Results 201 to 210 of about 206,257 (301)

Fracture risk and initiation of bone‐specific drug therapy following radical cystectomy with urinary diversion

open access: yesBJU International, EarlyView.
Objectives To assess the risk of fractures among patients with bladder cancer who underwent radical cystectomy (RC) with urinary diversion (UD), compared with matched referents from the general population. Patients/Subjects and Methods We identified 2908 patients who underwent RC between 2011 and 2019, and 13 669 matched referents in a nationwide ...
Mieke Van Hemelrijck   +10 more
wiley   +1 more source

Dietary melatonin and its benefits on cardiovascular disease

open access: yesBritish Journal of Pharmacology, EarlyView.
Cardiovascular disease remains the leading cause of mortality globally, with a disproportionate burden in low‐ and middle‐income countries. Melatonin, a hormone primarily produced by the pineal gland, exhibits notable antioxidant, anti‐inflammatory and immunomodulatory properties that may confer cardiovascular benefits.
Karabo Tisane   +2 more
wiley   +1 more source

Establishment of harmonized international reference ranges for plasma estradiol concentrations in postmenopausal women. [PDF]

open access: yesJ Clin Endocrinol Metab
Cui J   +22 more
europepmc   +1 more source

Elucidating PI3K/AKT/PTEN Pathway Alterations at Single‐Cell Level in CTCs From HR+/HER2− Metastatic Breast Cancer

open access: yesCancer Science, EarlyView.
Single CTC analysis revealed extensive inter‐ and intra‐patient heterogeneity of PI3K/AKT/PTEN pathway alterations in HR+/HER2− metastatic breast cancer, capturing both SNVs and CNAs, including PTEN loss‐of‐function events. Longitudinal CTC profiling also uncovered dynamic clonal evolution, highlighting its potential to complement tissue and ctDNA ...
Tania Rossi   +10 more
wiley   +1 more source

Progesterone receptor variants and hormone therapy use in postmenopausal endometrial polyps: a case-control study. [PDF]

open access: yesClinics (Sao Paulo)
Wajman M   +8 more
europepmc   +1 more source

Update on Menopause Hormone Therapy; Current Indications and Unanswered Questions

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Objective To provide clinicians involved in managing menopause with a summary of current evidence surrounding menopause hormone therapy (MHT). Design The authors evaluate and synthesize existing pooled evidence relating to MHT's clinical indications, efficacy, and safety and explore the limitations of existing data. Patients The review focuses
Annice Mukherjee, Susan R. Davis
wiley   +1 more source

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