Results 71 to 80 of about 89,178 (311)

Milk Extracellular Vesicles and Their Functional Potential in Osteoblast Activity: A Cross‐Species Comparison for Nutraceutical Development

Food Frontiers, EarlyView.
Label: mEVs and osteogenesis Description: This study reports a comparative analysis of mEVs isolated from raw milk EVs. Functional relevance of each type of mEVs is evaluated on cell proliferation and osteogenic differentiation of murine fibroblasts model.
Anna Maria Grimaldi, Jessie Santoro, Monica Barone, Patrizia Brigidi, Katia Pane, Monica Franzese, Marco Salvatore   +6 more
wiley   +1 more source

Biomechanical Computed Tomography analysis (BCT) for clinical assessment of osteoporosis. [PDF]

, 2020
The surgeon general of the USA defines osteoporosis as "a skeletal disorder characterized by compromised bone strength, predisposing to an increased risk of fracture." Measuring bone strength, Biomechanical Computed Tomography analysis (BCT), namely ...
Bouxsein, ML, Clarke, BL, Cosman, F, Keaveny, TM, Khosla, S, Orwoll, ES, Siris, ES   +6 more
core  

Sclerostin inhibition alleviates breast cancer-induced bone metastases and muscle weakness [PDF]

, 2019
Breast cancer bone metastases often cause a debilitating non-curable condition with osteolytic lesions, muscle weakness and a high mortality. Current treatment comprises chemotherapy, irradiation, surgery and anti-resorptive drugs that restrict but do ...
Brandt, Diana, Hesse, Eric, Pamperin, Jenny, Saito, Hiroaki, Schröder, Saskia, Taipaleenmäki, Hanna   +5 more
core   +1 more source

Plant‐derived extracellular vesicle‐like particles as novel osteoanabolic agents: Activating bone morphogenetic protein 2/Smads signaling axis for bone regeneration in postmenopausal osteoporosis

Interdisciplinary Medicine, EarlyView.
Illustration depicting the isolation of Dipsaci Radix derived extracellular vesicle‐like particles and their function in alleviating osteoporosis. (A) Extraction and characterization detection process of extracellular vesicle‐like particles derived from Dipsaci Radix roots. (B) Cell experiments in vitro, Dipsaci Radix derived extracellular vesicle‐like
Qing Zhao, Yue Cao, Zhengting Wu, Yingqi Cao, Qi You, Yuanyuan Xia, Xuejun Tan, Dongxiao Li, Tianxin Qiu, Xiuping Cai, Zhaodi Guo, Lei Zheng, Kewei Zhao   +12 more
wiley   +1 more source

Comparison of Physical Activity Levels and Quality of Life of Postmenoposal Women with and Without Osteoporosis

Türk Osteoporoz Dergisi, 2023
Objective:Osteoporosis is an important public health problem characterized by the deterioration of the microarchitecture of bone tissue and low bone mineral density.
Erkan Erol, Fatih Okan, Sevil Okan
doaj   +1 more source

Ubiquitylomes Analysis of the Whole blood in Postmenopausal Osteoporosis Patients and healthy Postmenopausal Women

Orthopaedic Surgery, 2019
Objectives To determine the mechanisms of ubiquitination in postmenopausal osteoporosis and investigate the ubiquitinated spectrum of novel targets between healthy postmenopausal women and postmenopausal osteoporosis patients, we performed ubiquitylome ...
Yi‐ran Yang, Chun‐wen Li, Jun‐hua Wang, Xiao‐sheng Huang, Yi‐feng Yuan, Jiong Hu, Kang Liu, Bo‐cheng Liang, Zhong Liu, Xiao‐lin Shi   +9 more
doaj   +1 more source

MicroRNA-34a prevents postmenopausal osteoporosis by promoting osteoclasts-induced osteoblasts differentiation and downregulating the proinflammatory cytokines [PDF]

, 2022
Wentao Lv, Xiaojie Chu, Zhonglei Bao, Xinyuan zhang, Jia Jia, Liyan Wang   +5 more
openalex   +1 more source

Assessment of trabecular bone score (TBS) in overweight/obese men: effect of metabolic and anthropometric factors [PDF]

, 2016
The "trabecular bone score" (TBS) indirectly explores bone quality, independently of bone mineral density (BMD). We investigated the effects of anthropometric and metabolic parameters on TBS in 87 overweight/obese men. We assessed BMD and TBS by DXA, and
Carnevale, Vincenzo, COSTANTINI, DANIELA, GNESSI, Lucio, LENZI, Andrea, LUBRANO, Carla, Migliaccio, Silvia, MORANO, Susanna, Nieddu, Luciano, Romagnoli, Elisabetta   +8 more
core   +1 more source

Human Cyclophilins—An Emerging Class of Drug Targets

Medicinal Research Reviews, EarlyView.
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova, Hana Navratilova, Kamil Musilek, Ondrej Benek   +3 more
wiley   +1 more source

A Risk Reduction Program for Osteoporosis Complications among Postmenopausal Women: A Quasi- Experimental Design

BMC Women's Health
Background Osteoporosis is considered a common health problem in postmenopausal women. Therefore, reducing modifiable risk factors through dietary, lifestyle changes, and compliance of pharmacological therapy for those women at a significant risk of ...
Fatin Abdel Raheem Mostafa Zewail, Faten Khayrat El-Guindi, Ferial Fouad Melika   +2 more
doaj   +1 more source