Results 51 to 60 of about 282,351 (359)

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

Molecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková, Marie Ehrlichová, Alžběta Spálenková, Ivona Krus, Simona Šůsová, Viktor Hlaváč, Vlasta Němcová, Renata Koževnikovová, Markéta Trnková, David Vrána, Jiří Gatěk, Kateřina Kopečková, Marcela Mrhalová, Soňa Měšťáková, Pavel Souček   +14 more
wiley   +1 more source

Lack of association of ovariectomy-induced obesity with overeating and the reduction of physical activities

Biochemistry and Biophysics Reports, 2019
Obesity commonly occurs in postmenopausal women, increasing the risk of various diseases. Estrogen can prevent obesity by activating lipid metabolism and suppressing depressive behavior.
Eiji Nishio, Takanori Hayashi, Masashi Nakatani, Noriko Aida, Risa Suda, Takuma Fujii, Toru Wakatsuki, Shinichiro Honda, Nobuhiro Harada, Yohei Shimono   +9 more
doaj   +1 more source

Cystic Ovarian Teratoma: Clinical and Radiographic Insights Into Chronic Pelvic Pain

Aging and Cancer, EarlyView.
An incidental benign mature cystic ovarian teratoma on imaging and discuss common imaging modalities. ABSTRACT In this case report, we present the clinical course of an 88‐year‐old woman with chronic pelvic pain attributed to an incidental benign mature cystic ovarian teratoma on imaging and discuss common imaging modalities and discussions with ...
Hashim U. Ali, Fahad H. Malik, Mohammad M. Zia, Ashar Ahmed, Mahfujul Z. Haque, Masood Siddiqui   +5 more
wiley   +1 more source

The Interaction of Type II Diabetes and Gonadal Steroids on Cognition in Middle-Aged Women [PDF]

, 2019
Diabetes is not commonly thought to be a women’s health issue, however, it appears to have an association with increased cognitive impairment in women during menopause as compared to women without diabetes (Espeland et al., 2011).
Bates, Kara A
core   +1 more source

Managing menopausal symptoms and associated clinical issues in breast cancer survivors [PDF]

, 2017
Objective: Review evidence to guide management of menopausal signs and symptoms in women after breast cancer and make recommendations accordingly. Evidence: Randomized controlled clinical trials, observational studies, evidence-based guidelines, and
Davis, Susan R., Gompel, Anne, Lumsden, Mary Ann, Pinkerton, JoAnn V., Santen, Richard J., Stuenkel, Cynthia A.   +5 more
core   +1 more source

Endometrial fluid in postmenopausal women

International Journal of Gynecology & Obstetrics, 2009
[1] World Health Organization. Mechanism of Action, Safety, and Efficacy of Intrauterine Devices. Geneva: World Health Organization; 1987. [2] Miller BJ, Schache DJ. Colorectal injury: where do we stand with repair? Aust NZ J Surg 1996;66(6):348–52. [3] Nceboz US, Ozcakir HT, Uyar Y, Caglar H.
İnceboz, Ümit, Uyar, Yıldız, Baytur, Yeşim, Kandiloğlu, Ali Rıza   +3 more
openaire   +5 more sources

Chronic Pain in Parkinson’s Disease: Prevalence, Sex Differences, Regional Anatomy and Comorbidities

Annals of Clinical and Translational Neurology, EarlyView.
Chronic pain affected 66.2% of 10,631 individuals with Parkinson's disease, with higher prevalence and severity in females. Pain most often involved the buttocks, lower back, neck, and knees, and was linked to depression, sleep disorders, and osteoarthritis.
Natalia S. Ogonowski, Freddy Chafota, Fangyuan Cao, Amanda Wei Yin Lim, Victor Flores‐Ocampo, Santiago Díaz‐Torres, Zuriel Ceja, Luis M. García‐Marín, Scott F. Farrell, Kishore R. Kumar, Jane Alty, George D. Mellick, Trung Thành Ngô, Miguel E. Rentería   +13 more
wiley   +1 more source

Corneal topographic changes in premenopausal and postmenopausal women

BMC Ophthalmology, 2007
Background To asses the effect of menopause on the corneal curvature changes using corneal computerized videokeratography (CVK) in premenopausal and postmenopausal healthy women. Methods Thirty-six postmenopausal women with mean ages of 49.2 (range 39 to
Aytan Hakan, Calıskan Ahmet, Demirturk Fazli, Demir Helin, Aydin Erdinc, Erkorkmaz Unal   +5 more
doaj   +1 more source

Serum uric acid levels in older adults: Associations with clinical outcomes and implications for reference intervals in those aged 70 years and over

Arthritis Care &Research, Accepted Article.
Objectives Reports have linked both high and low serum uric acid (SUA) levels to adverse health outcomes. This study aimed to establish a reference interval for SUA in older adults and assessed its association with clinically relevant outcomes in relatively healthy, community‐dwelling individuals aged 70 and older.
Amanda J Rickard, Cammie Tran, Hans G Schneider, Flavia M Cicuttini, Anita E Wluka, Ego Seeman, Johannes T Neumann, Md Nazmul Karim, Zhen Zhou, Sultana Monira Hussain, David P Q Clark, Daniel Clayton‐Chubb, Andrew M Tonkin, Lawrence J Beilin, Robyn L Woods, John J McNeil   +15 more
wiley   +1 more source

Comparative Study of Lipid Profile in Premenopausal and Postmenopausal Women [PDF]

Walawalkar International Medical Journal, 2021
Introduction: Menopause is a natural aging process that signifies the end of reproductive years with cessation of cyclic ovarian function as manifested by cyclic menstruation. Ovaries fail completely to produce estrogen.
Seema Takras1, Sudha Karadkhedkar1 and Shreechakradhar Mungal1
doaj