Results 31 to 40 of about 93,068 (259)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

An investigation of postmortem urotensin II receptor levels in brain and kidney tissues in a rat model of cardiac ischemia

Journal of Forensic Science and Medicine, 2018
This study aimed to investigate changes in postmortem urotensin II receptor (UTR) levels in brain and kidney tissues in a rat model of cardiac ischemia. The rats were divided into two groups: a control group and a cardiac ischemia-induced group.
Mustafa Talip Sener, Erol Akpinar, Elif Cadirci, Zekai Halici, Irfan Cinar, Ahmet Nezih Kok   +5 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Impact of high intensity ultrasound on the quality and preservation period of blue shrimp (Litopenaeus stylirostris) muscle

Journal of Fisheries
Due to the limited shelf life of aquatic products, the use of advanced technologies to extend their freshness has become more popular recently. This study aimed to assess the impact of high-intensity ultrasound (HIU) on the quality of blue shrimp ...
Wilfrido Torres-Arreola, Rey Partida-Rivera, Victor M. Ocaño-Higuera, Saúl Ruíz-Cruz, Guadalupe Miroslava Suarez-Jimenez, Nathaly Montoya-Camacho, José Carlos Rodríguez-Figueroa, Enrique Márquez-Rios   +7 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Yoğun Bakım Hemşireleri: Ölümün İlk Tanıkları

Yoğun Bakım Hemşireliği Dergisi
Ölüm, yaşamın ve fiziksel varlığın sona erdiği bir durumu ifade eder. Klinik ölüm, hücresel ölüm, agoni (can çekişme), yalancı ölüm ve beyin ölümü gibi kavramların ayırt edilmesi sağlık çalışanları için önem arz etmektedir.
Halil İlhan Aydoğdu, Esra Özkan
doaj   +1 more source

Histological and miRNAs postmortem changes in incisional wound

Egyptian Journal of Forensic Sciences, 2019
Background Regarding postmortem estimation, the evaluation of early histological and miRNA molecular changes have been of great concerns among forensic scientists due to uncertainty of known conventional methods.
Samah F. Ibrahim, Mona M. Ali, Hoda Basyouni, Laila A. Rashed, Eman A. E. Amer, Dalia Abd El-Kareem   +5 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

A Systematic Review About Postmortem Pink Teeth: Forensic Classification, Diagnostic Value, and Analysis Methods

Diagnostics
Background: The phenomenon of pink teeth represents a notable observation in forensic science, although its interpretation remains complex and not directly attributable to a specific cause of death. Methods: This systematic review provides an updated and
Isabella Aquila, Saverio Gualtieri, Aurora Princi, Matteo Antonio Sacco   +3 more
doaj   +1 more source